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Manufacturing Execution System Jobs (NOW HIRING)

R&D Manufacturing Director

Herndon, VA · On-site

$150K - $225K/yr

Select, implement, and operationalize a Manufacturing Execution System (MES) aligned with optical and laser manufacturing needs * Resolve nonconformances and production issues using structured root ...

R&D Manufacturing Director

Herndon, VA · On-site

$150K - $225K/yr

... a Manufacturing Execution System (MES), and helping to scale production capacity. The role serves as the operational link between engineering, configuration management, quality, supply chain ...

Independently perform visual inspection, advanced visual inspection, palletizing, cleaning, inspection hood preparation, manufacturing execution system operations, and exception handling following ...

The Director will be deeply involved in daytoday manufacturing operations while also driving longterm capability improvements, updating core processes, implementing a Manufacturing Execution System ...

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Manufacturing Execution System information

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$40.5K

$110.2K

$158.5K

How much do manufacturing execution system jobs pay per year?

As of Jul 24, 2026, the average yearly pay for manufacturing execution system in the United States is $110,216.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,000.00 and $142,500.00 per year, depending on experience, location, and employer.

What is a Manufacturing Execution System job?

A Manufacturing Execution System (MES) job involves overseeing and managing software solutions that monitor, control, and optimize manufacturing processes on the shop floor. Professionals in this role ensure seamless data flow between production equipment, operators, and enterprise systems to improve efficiency, quality, and compliance. Responsibilities often include system implementation, configuration, troubleshooting, and continuous improvement initiatives. MES roles are crucial in industries like automotive, pharmaceuticals, and electronics, where real-time production tracking is essential.

What are the typical day-to-day responsibilities of someone working in a Manufacturing Execution System (MES) role?

Professionals in an MES role are responsible for configuring, monitoring, and optimizing the software systems that track and control manufacturing processes on the production floor. Daily tasks often include troubleshooting system issues, analyzing production data to support decision-making, and collaborating closely with production, quality, and IT teams to ensure seamless workflow integration. They may also be involved in implementing new system features, maintaining system documentation, and training end-users on MES functionalities. This role requires a proactive approach to problem-solving and strong collaboration to ensure production efficiency and product quality.

What are the key skills and qualifications needed to thrive in the Manufacturing Execution System position, and why are they important?

To thrive in a Manufacturing Execution System (MES) role, you need a solid understanding of manufacturing processes, strong analytical skills, and often a degree in engineering, information technology, or a related field. Familiarity with MES platforms (such as Siemens Opcenter, Rockwell FactoryTalk, or GE Proficy), database management, and relevant certifications are commonly required. Effective communication, problem-solving, and project management abilities are crucial soft skills for success in this position. These competencies ensure seamless integration of technology on the production floor, enabling efficient operations and quick response to production challenges.

More about Manufacturing Execution System jobs
What cities are hiring for Manufacturing Execution System jobs? Cities with the most Manufacturing Execution System job openings:
What states have the most Manufacturing Execution System jobs? States with the most job openings for Manufacturing Execution System jobs include:
What job categories do people searching Manufacturing Execution System jobs look for? The top searched job categories for Manufacturing Execution System jobs are:
Infographic showing various Manufacturing Execution System job openings in the United States as of July 2026, with employment types broken down into 89% Full Time, 8% Part Time, and 3% Contract. Highlights an 89% Physical, 4% Hybrid, and 7% Remote job distribution, with an average salary of $110,216 per year, or $53 per hour.
Engineer II, Manufacturing Execution Systems

Engineer II, Manufacturing Execution Systems

Moderna

Norwood, MA • On-site

Full-time

Posted 26 days ago


Moderna rating

9.2

Company rating: 9.2 out of 10

Based on 10 frontline employees who took The Breakroom Quiz

4th of 74 rated pharmaceutical


Job description

Job Summary:
Moderna is a leading mRNA technology company focused on transforming medicine. The Engineer II will serve as a frontline partner for Operations, providing user support for manufacturing digital systems and implementing improvements across the manufacturing network.
Responsibilities:
• Serve as the first point of contact for shop-floor users; troubleshoot complex issues, resolve, and document issues for Apprentice Tempo, Syncade, DeltaV, Aveva SCADA Platform, Aveva PI, and BMS.
• Perform structured troubleshooting across application, configuration, and basic infrastructure layers; escalate effectively when needed.
• Coordinate with Operations, Quality, and IT to restore service quickly and minimize production impact.
• Maintain and improve support knowledge (runbooks, KB articles, SOPs) and provide targeted user coaching and quick tips to reduce repeat issues.
• Execute standard change-control activities related to support (e.g., minor configuration updates, record corrections, documentation) in alignment with GxP and data-integrity expectations.
• Monitor system health and alerts; identify patterns and propose corrective and preventive actions (CAPAs) or continuous improvement suggestions.
• Participate in planned maintenance windows for support validation and post-maintenance checks.
• Contribute to compliance activities (deviations, investigations, periodic reviews) from a systems-support perspective.
• Mentor junior team members through shadowing, ticket reviews, and feedback on documentation; support onboarding and skills development to build a resilient frontline support function.
Qualifications:
Required:
• Bachelor’s degree in Information Technology, Engineering, or a related field.
• 2-3 years of hands-on experience with Manufacturing Execution Systems.
• Clear communication skills, with the ability to convey complex information in an understandable manner to various stakeholders.
• Ability to work first, second, or third shifts to support 24/7 operation.
• This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.
• Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship.
Preferred:
• Depth in two or more systems: Tempo, Syncade, Aveva SCADA, DeltaV, or BMS, with familiarity in their integrations.
• Experience in MES business processes for electronic batch record execution and a working knowledge of automation systems.
• Working understanding of cGMP manufacturing operations, GAMP, and CSV/change-control practices.
• Demonstrated strength in incident triage, root-cause analysis, and clear written documentation.
• Ability to partner effectively with cross-functional stakeholders under time-sensitive conditions.
• Understanding of integrated digital systems and be able to triage issues spanning multiple systems.
• Strong customer-service mindset; confident facilitating user training and delivering concise how-to.
• Experience coaching or mentoring junior engineers and contributing to team knowledge-sharing practices.
• Continuous-improvement orientation—experience reducing ticket volume through standardization or automation initiatives.
Company:
Moderna Therapeutics is a biotechnology company that develops medicines and vaccines based on messenger RNA (mRNA) technology. Founded in 2010, the company is headquartered in Cambridge, USA, with a team of 1001-5000 employees. The company is currently Late Stage.

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About Moderna

Sourced by ZipRecruiter

In just over a decade, Moderna has evolved from a research-focused company in the messenger RNA (mRNA) field to a leading enterprise with a diverse clinical portfolio of vaccines and therapeutics. With a strong intellectual property portfolio and state-of-the-art manufacturing capabilities, Moderna collaborates with global partners to advance groundbreaking science and achieve rapid scaling of production. Notably, Moderna's mRNA platform has enabled the development of therapies for various diseases, including infectious diseases, immuno-oncology, and cardiovascular conditions. Recognized as a top biopharmaceutical employer, Moderna fosters an inclusive and smoke-free work environment. The company is dedicated to equal employment opportunities and non-discrimination, ensuring that all employees and applicants are treated with respect and without bias based on factors like race, gender, religion, disability, or sexual orientation. Moderna is also committed to providing reasonable accommodations for individuals with disabilities, in accordance with applicable laws. To know more, visit www.modernatx.com.

Industry

Manufacturing

Company size

501 - 1,000 Employees

Headquarters location

Cambridge, MA, US

Year founded

2010

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