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Manager Dmpk Jobs in Indiana (NOW HIRING)

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Manager Dmpk information

What does a manager DMPK do?

A Manager DMPK (Drug Metabolism and Pharmacokinetics) oversees studies and teams that evaluate how drugs are absorbed, distributed, metabolized, and excreted in the body. They design and manage experiments, interpret data, and ensure regulatory compliance. This role often includes collaborating with project teams, supporting drug development decisions, and mentoring junior scientists. Managers in DMPK play a key part in delivering safe and effective drug candidates for clinical development.

What skills and qualifications are needed to be a manager DMPK?

To thrive as a Manager DMPK, you need advanced knowledge in pharmacokinetics, drug metabolism, and a relevant advanced degree (PhD or MS) in pharmaceutical sciences or a related field. Expertise with analytical tools like LC-MS/MS, pharmacokinetic modeling software, and familiarity with regulatory guidelines are typically required. Strong leadership, communication, and project management skills help you guide teams and collaborate effectively across departments. These expertise and qualities are essential for ensuring the safe and efficient progression of drug candidates through development pipelines.

What challenges does a manager DMPK face when leading cross-functional drug development teams?

A Manager DMPK often encounters challenges in aligning the goals and timelines of different departments, such as pharmacology, toxicology, and clinical development. Coordinating complex data from multiple sources and ensuring clear communication between teams is crucial for successful project progression. Additionally, staying updated with regulatory requirements and integrating new scientific methodologies can require proactive problem-solving and adaptability. Building strong relationships across functions helps address these challenges and keeps projects on track.

What is the difference between Manager Dmpk vs Pharmacovigilance Manager?

AspectManager DmpkPharmacovigilance Manager
Required CredentialsBachelor's or Master’s in Life Sciences, experience in DMPKBachelor's or Master’s in Pharmacy, Pharmacology, or Life Sciences
Work EnvironmentResearch labs, drug development teamsRegulatory agencies, clinical safety teams
Employer & Industry UsagePharmaceutical R&D, biotech companiesPharmaceutical companies, regulatory bodies
Common Search & ComparisonYesYes

The Manager Dmpk focuses on drug metabolism and pharmacokinetics studies within drug development, while the Pharmacovigilance Manager oversees drug safety and adverse event monitoring. Both roles require scientific backgrounds but differ in their focus areas and work environments, with Dmpk managers more involved in research and pharmacovigilance managers in safety regulation compliance.

What are the most commonly searched types of Dmpk jobs in Indiana?

The most popular types of Dmpk jobs in Indiana are:

What are popular job titles related to Manager Dmpk jobs in Indiana?

For Manager Dmpk jobs in Indiana, the most frequently searched job titles are:

What cities in Indiana are hiring for Manager Dmpk jobs?

Cities in Indiana with the most Manager Dmpk job openings:

Infographic showing various Manager Dmpk job openings in Indiana as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 79% Physical, 4% Hybrid, and 17% Remote job distribution.

Principal Research Scientist - Medicinal Chemist

Elanco Animal Health Incorporated

Indianapolis, IN • On-site

Full-time

Retirement, PTO

Re-posted 16 days ago


Elanco rating

7.8

Company rating: 7.8 out of 10

Based on 25 frontline employees who took The Breakroom Quiz

50th of 86 rated pharmaceutical


Job description

At Elanco (NYSE: ELAN) - it all starts with animals!
As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets. At Elanco, we are driven by our vision of Food and Companionship Enriching Life and our purpose - all to Go Beyond for Animals, Customers, Society and Our People.
At Elanco, we pride ourselves on fostering a diverse and inclusive work environment. We believe that diversity is the driving force behind innovation, creativity, and overall business success. Here, you'll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights.
Making animals' lives better makes life better - join our team today!
Your Role:
Principal Research Scientist - Medicinal Chemist
As a Principal Research Scientist in Medicinal Chemistry, you will be a key figure in our small molecule drug discovery engine, guiding the design and synthesis of innovative medicines that improve the health and well-being of animals. You will apply your scientific expertise to advance multiple therapeutic programs, from lead generation to development candidate selection. Partnering with a global, cross-functional team of scientists, you will leverage cutting-edge technologies like AI/ML and DNA-Encoded Libraries to solve complex chemical challenges. This is an exciting opportunity to make a significant impact on our discovery portfolio and help shape the future of our growing research team in Indianapolis.
Your Responsibilities:
  • Guide the design and optimization of novel small molecules by applying advanced synthetic strategies and integrating biological, pharmacological, and ADME/PK data to manage Structure-Activity Relationship (SAR) campaigns.

  • Serve as a key medicinal chemistry figure on multidisciplinary project teams, collaborating with partners in Biology, Pharmacology, DMPK, Toxicology, and Computational Sciences to strategically advance discovery programs.

  • Manage and coordinate synthetic chemistry efforts with external Contract Research Organizations (CROs) and internal partners, ensuring the efficient execution of project goals and timelines.

  • Leverage cutting-edge drug discovery technologies, including DNA-Encoded Libraries (DEL), computational chemistry, and AI/ML-enabled tools, to accelerate hit identification and lead optimization.

  • Promote scientific excellence and data integrity while providing mentorship and technical guidance to junior scientists, fostering a culture of innovation and collaboration.

What You Need to Succeed (minimum qualifications):
  • Education: PhD in Medicinal Chemistry, Organic Chemistry, or a related scientific discipline.

  • Experience: A minimum of 6 years of relevant industry experience in medicinal chemistry within a pharmaceutical, biotechnology, or animal health research environment.

  • Top Skills: Demonstrated expertise in modern medicinal chemistry, including the design and multi-step synthesis of complex small molecules, and a strong understanding of Structure-Activity Relationships (SAR), pharmacology, and ADME/PK principles. Proven ability to autonomously manage scientific initiatives within a cross-functional team and manage external collaborations with CROs.

What will give you a strong candidate profile (preferred qualifications):
  • Postdoctoral experience.

  • Experience applying modern drug discovery technologies such as DNA-Encoded Libraries (DEL), computational chemistry, or AI/ML-enabled molecular design.

  • A strong track record of advancing small-molecule discovery programs toward preclinical development, evidenced by significant patent and/or publication contributions.

  • Prior research experience in the animal health industry.

  • Expertise in peptide chemistry, macrocycles, or related drug modalities.

Additional Information:
  • Travel: Less than 10%

  • Location: Global Elanco Headquarters - Indianapolis, IN - Hybrid Work Environment

Don't meet every single requirement? Studies have shown underrecognized groups are less likely to apply to jobs unless they meet every single qualification. At Elanco we are dedicated to building a diverse and inclusive work environment. If you think you might be a good fit for a role but don't necessarily meet every requirement, we encourage you to apply. You may be the right candidate for this role or other roles!
Elanco Benefits and Perks:
We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:
  • Multiple relocation packages

  • Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)

  • 8-week parental leave

  • 9 Employee Resource Groups

  • Annual bonus offering

  • Flexible work arrangements

  • Up to 6% 401K matching

Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job-related criteria and/or transferrable skills. These tools help ensure a consistent, structured evaluation, but they do not make hiring decisions. All decisions involve a human reviewer. For more information on how we handle personal data, please see our Elanco Workforce Privacy Notice.

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