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Lims Software Jobs in California (NOW HIRING)

They are seeking a Staff Software Engineer with expertise in Laboratory Information Management Systems (LIMS) to design and scale software solutions that support complex laboratory workflows.

Integrate LIMS with upstream and downstream systems (instruments, ELNs, EMRs/EHRs, data warehouses, APIs). * Ensure systems meet regulatory and compliance requirements (e.g., CLIA, CAP, HIPAA, 21 CFR ...

We are looking for a Staff Software Engineer with deep expertise in Laboratory Information ... This role is ideal for someone who has worked hands-on with LIMS platforms such as Labbit ...

Recording and reporting of analysis results using Honeywell web-based LIMS software. Daily communication (phone, fax and email) with customers. Calibration and routine maintenance of laboratory ...

Sr. Director, Lab Pipelines and LIMS

San Diego, CA · On-site

$112K - $147K/yr

We are seeking a Sr. Director, Lab Pipelines & LIMS to lead the strategy, development, and operation of critical software systems that power our diagnostic workflows. This leader will oversee ...

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Lims Software information

See California salary details

$47.4K

$110.4K

$163.8K

How much do lims software jobs pay per year?

As of Sep 8, 2026, the average yearly pay for lims software in California is $110,380.00, according to ZipRecruiter salary data. Most workers in this role earn between $88,800.00 and $128,300.00 per year, depending on experience, location, and employer.

What is LIMS software?

LIMS software, or Laboratory Information Management System software, is a specialized tool used to manage data, workflows, and processes in laboratories. It helps automate sample tracking, test results, inventory management, and compliance with industry regulations. LIMS software increases efficiency, improves data accuracy, and streamlines laboratory operations by centralizing information and providing real-time access to data. Laboratories in industries such as healthcare, pharmaceuticals, food safety, and environmental testing commonly use LIMS to ensure quality and traceability.

What are the key skills and qualifications needed to thrive as a LIMS software specialist?

To thrive as a LIMS (Laboratory Information Management System) Software Specialist, you need expertise in laboratory workflows, database management, and computer science, typically supported by a degree in IT, life sciences, or a related field. Familiarity with LIMS platforms (such as LabWare or STARLIMS), scripting languages (e.g., SQL, Python), and relevant certifications like CLIMSE (Certified LIMS System Engineer) are often required. Strong problem-solving, communication, and project management skills help specialists effectively bridge technical and user needs. These competencies are critical for ensuring accurate data management, system efficiency, and successful collaboration between laboratory and IT teams.

What are some typical challenges faced when implementing and maintaining LIMS software in a laboratory setting?

One common challenge in working with LIMS (Laboratory Information Management System) software is ensuring smooth integration with existing laboratory instruments and workflows, as each lab may have unique requirements. Additionally, maintaining data integrity, regulatory compliance, and user training can be ongoing concerns, especially as new features or updates are introduced. Collaboration with IT, lab technicians, and quality assurance teams is essential for troubleshooting issues and optimizing the system to meet evolving needs. Effective communication and adaptability are key to overcoming these challenges and maximizing the benefits of LIMS software.

What is the difference between Lims Software vs Laboratory Technician?

AspectLims SoftwareLaboratory Technician
CredentialsTypically requires a degree in life sciences or IT, sometimes certifications in laboratory information managementRequires a degree or diploma in laboratory sciences or related field
Work EnvironmentUsed in labs for data management, often in office or computer stationsHands-on in laboratory settings performing tests and sample analysis
Employer & IndustryLaboratories, biotech, pharmaceutical companies, research institutionsHospitals, research labs, industrial labs

While Lims Software focuses on managing laboratory data and streamlining workflows, Laboratory Technicians perform the actual testing and analysis. Both roles are essential in lab operations but differ in responsibilities and work environment.

What does LIMS software do?

LIMS (Laboratory Information Management System) software helps laboratories manage data, track samples, automate workflows, and ensure compliance with industry standards. It is used by lab technicians and managers to improve efficiency, data accuracy, and reporting capabilities.

What is the most popular LIMS software?

Laboratory Information Management System (LIMS) software such as LabWare, STARLIMS, and Thermo Fisher's SampleManager are among the most widely used in the industry. These platforms are popular due to their comprehensive features, scalability, and support for regulatory compliance, making them common choices for labs seeking efficient data management and automation.
Infographic showing various Lims Software job openings in California as of August 2026, with employment types broken down into 82% Full Time, 13% Part Time, and 5% Contract. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution, with an average salary of $110,380 per year, or $53.1 per hour.

Staff Software Engineer, LIMS

San Diego, CA

$174K - $185K/yr

Full-time

Posted 19 days ago


Job description

Location: San Diego, CA

Job Type: Full-Time

Salary: $174,000 - $185,000

 
Position Overview: 
We're seeking a technical leader to own the implementation of our LIMS platform, connecting sample tracking to lab automation and instrumentation across laboratory workflows. You'll own the LIMS implementation end to end: working with laboratory scientists, clinical operations, and the automation team to define requirements, then building and configuring the system to match. You'll connect LIMS to lab instruments, automation devices, and other internal systems, and own the sample-tracking data model that everything downstream depends on. 

You'll need to be a highly effective communicator, comfortable sitting with lab scientists and automation engineers to translate how they work into software, rather than just taking a spec and building to it. Deep hands-on LIMS experience in clinical or molecular diagnostics labs is required; curiosity and fast learning matter just as much, since this role means going deep on new lab technologies as they come up. 

This role is a unique opportunity to own a central piece to the overall success of the company. 

Responsibilities:

  • Build out and/or extend the LIMS. Ensure that the LIMS supports straightforward definition and use of workflows, so LIMS is the source of truth for every sample's state through the lab. 
  • Build the integration layer between LIMS and the lab-automation devices — worklist generation, step logging back to LIMS, error capture, reagent lot tracking (lot ID, expiration, usage per sample). 
  • Model the sample → preparation → assay execution → analysis → results traceability chain for high-throughput laboratory workflows. 
  • Own the data model and sample chain-of-custody contract that downstream systems (ordering systems, analysis orchestration, reporting portals) rely on. 
  • Ensure every step is recorded to meet 21 CFR Part 11 audit requirements. 
  • Work with the Director of Lab Automation on the software ↔ hardware interfaces. 
  • Interact with lab and other end users to map out requirements and priorities and ensure that user acceptance criteria are met. 
  • Contribute to CI/CD, code review, and testing practices for regulated systems. 

Qualifications:

Required:
  • 7+ years building software for clinical or molecular diagnostics labs. 
  • Hands-on LIMS experience — customization, extension, and integration with lab instrumentation. Direct experience with at least one commercial or open-source LIMS (e.g. Senaite / Bika, LabKey, OpenSpecimen, Benchling, LabWare, STARLIMS, LabVantage, or Sapio) or direct experience developing a custom LIMS used with a high-volume production assay. 
  • Sample-tracking data-model experience for high-throughput complex laboratory workflows; multi-step, multi-instrument, batch-level QC gates, per-sample lineage, reagent lot tracking. 
  • Full stack programming experience with modern programming languages and best practices, spanning the UI, APIs, and backend databases along with git-based workflows and CI/CD in a validated system  
  • Regulated-environment experience, e.g. 21 CFR Part 11, ISO 13485, ISO 15189, CAP / CLIA, or GxP. 
  • BS or MS in Computer Science, Bioengineering, or a related field or equivalent industry experience. Track record with production systems weighs more than credentials. 
Nice to have:
  • Comfortable with lab-automation APIs, e.g. Hamilton STAR, SPT Firefly, Thermo KingFisher, etc. You talk to them; you don't need to script the methods. 
  • Experience with HL7 v2, FHIR, LIS, ASTM E1394, or IHE profiles for lab / EMR interoperability. 
  • Familiarity with cloud (AWS, Azure, or GCP) providers and services available — enough to work with cloud-hosted services. 

We are an equal opportunity employer. We thrive on diversity and collaboration.