Lifecycle Manager Jobs in Ohio (NOW HIRING)

Career Category
Engineering
Job Description
Join Amgen's Mission of Serving Patients
At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.
Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Senior Manager Engineering
What you will do
Let's do this. Let's change the world.
In this vital role, you will provide leadership for Facilities & Engineering operations supporting Amgen Ohio (AOH), a state-of-the-art final drug product manufacturing facility. You will be responsible for the safe, reliable, compliant, and efficient operation of site utility, facility, and infrastructure systems that support commercial manufacturing operations.
Reporting to the Director of Facilities & Engineering, the Senior Manager will lead a team of engineers and technical professionals responsible for utility systems, sustainability initiatives, asset lifecycle management, and engineering support activities. The role will work closely with Reliability Engineering, Maintenance, Manufacturing, Quality, EHS, and Capital Projects to ensure site operational readiness and long-term asset performance.
The Senior Manager will be a key leader in driving reliability, operational excellence, sustainability, inspection readiness, and continuous improvement across the AOH campus.
Responsibilities
Engineering and Utility Systems Leadership

• Provide leadership, coaching, and technical direction to a team of Facilities & Engineering professionals responsible for plant utilities, HVAC, building automation systems, electrical distribution, refrigeration systems and facility infrastructure.
• Ensure safe, reliable, and compliant operation of utility and facility systems supporting commercial packaging manufacturing.
• Develop and implement engineering strategies that improve asset reliability, operational performance, and lifecycle sustainability.
• Partner closely with Reliability Engineering to drive asset performance, condition-based monitoring, predictive maintenance strategies, and risk reduction initiatives.
• Serve as the engineering owner for critical utility and facility systems, ensuring robust lifecycle management and system performance.

Operational Excellence and Reliability

• Lead initiatives to improve equipment reliability, system availability, and operational efficiency across site infrastructure.
• Utilize performance metrics and engineering data to identify opportunities for continuous improvement and risk mitigation.
• Drive root cause investigations and corrective actions for significant utility, facility, or infrastructure events.
• Support the development and implementation of reliability-centered maintenance and asset management strategies.
• Foster a culture of operational excellence through Lean, Continuous Improvement, and problem-solving methodologies.

Compliance and Inspection Readiness

• Ensure utility systems operate in accordance with cGMP, regulatory, safety, and environmental requirements.
• Maintain a state of inspection readiness and support internal audits, regulatory inspections, and partner visits.
• Ensure engineering documentation, procedures, change controls, deviations, CAPAs, and maintenance practices remain compliant and effective.
• Collaborate with Quality and Validation organizations to support qualification, requalification, and ongoing compliance activities.

Capital Projects and Asset Lifecycle Management

• Support site capital investment planning and execution related to utility, facility, and infrastructure systems.
• Provide engineering oversight for facility upgrades, expansions, equipment replacements, and infrastructure modernization initiatives.
• Drive long-range asset lifecycle planning and support Amgen's Global Lifecycle Asset Management programs.
• Collaborate with project teams to ensure successful startup, commissioning, qualification, and operational integration of new assets.

Sustainability and Business Operations

• Lead sustainability initiatives supporting Amgen's environmental and energy reduction commitments.
• Support utility forecasting, operating budgets, capital planning, and resource allocation activities.
• Collaborate with internal and external partners to optimize utility consumption, operational efficiency, and infrastructure performance.
• Ensure business continuity through proactive infrastructure planning, risk management, and contingency preparedness.

People Leadership

• Build, develop, and retain a high-performing engineering organization.
• Establish clear goals, performance expectations, and development plans for team members.
• Foster a collaborative culture focused on safety, accountability, innovation, and continuous learning.
• Drive engagement and technical capability development across the Facilities & Engineering organization.

What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a collaborative leader with these qualifications.
Basic Qualifications
Doctorate degree and 2 years of Engineering experience
OR
Master's degree and 6 years of Engineering experience
OR
Bachelor's degree and 8 years of Engineering experience
OR
Associate's degree and 10 years of Engineering experience
OR
High school diploma / GED and 12 years of Engineering experience
In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above
Preferred Qualifications

• Bachelor's degree in Mechanical Engineering, Chemical Engineering, Electrical Engineering, or related technical discipline.
• 8+ years of experience in Facilities, Utilities, Engineering, Reliability, or related technical functions.
• 5+ years of leadership experience managing engineering or technical teams.
• Experience within pharmaceutical, biotechnology, medical device, or other highly regulated manufacturing environments.
• Strong knowledge of plant utilities, clean utilities, HVAC systems, facility infrastructure, and building management systems.
• Experience supporting GMP manufacturing operations and regulatory inspections.
• Knowledge of reliability engineering principles, asset management programs, and predictive maintenance technologies.
• Experience with computerized maintenance management systems (CMMS) and asset management tools.
• Demonstrated success leading continuous improvement, operational excellence, and sustainability initiatives.
• Strong project management, problem-solving, and decision-making capabilities.
• Excellent communication, collaboration, and stakeholder management skills.
• Ability to manage multiple priorities in a fast-paced manufacturing environment.
• Ability to provide occasional off-hours support for critical business and operational needs.

What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
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Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Salary Range
148,715.15USD -201,202.85 USD