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Lead Systems Engineer Jobs in Raleigh, NC (NOW HIRING)

Systems Engineer

Raleigh, NC ยท On-site

$145K - $175K/yr

Lead system-level engineering for complex pharmaceutical equipment * Serve as the primary technical resource for two aseptic filling systems * Drive IQ/OQ qualification activities and system ...

The Lead Systems Admin drives the design and implementation of robust, secure, and scalable server ... Build reusable automation frameworks and define platform standards along with Systems Engineers ...

Systems Engineer Job Details Deliver engineering specifications, assist with functional ... Develop recommendations in support of objectives and lead technical implementation of backup ...

About the role We are looking for a Lead MarTech Engineer to own and advance the systems that enable our marketing organization. This is a hands-on technical leadership role combining engineering ...

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Lead Systems Engineer information

See Raleigh, NC salary details

$88.5K

$193.8K

$245.9K

How much do lead systems engineer jobs pay per year?

As of Aug 28, 2026, the average yearly pay for lead systems engineer in Raleigh, NC is $193,762.00, according to ZipRecruiter salary data. Most workers in this role earn between $162,300.00 and $245,900.00 per year, depending on experience, location, and employer.

What does a lead systems engineer do?

A Lead Systems Engineer oversees the design, integration, and management of complex systems within an organization. They coordinate teams, ensure system reliability and security, and often serve as the primary technical point of contact for projects. Their responsibilities include evaluating system requirements, troubleshooting issues, and ensuring that all components work harmoniously. Lead Systems Engineers also mentor junior staff and collaborate with other departments to ensure project success.

What are the key skills and qualifications needed to thrive as a lead systems engineer?

To thrive as a Lead Systems Engineer, you need advanced knowledge in systems architecture, network administration, and troubleshooting, usually backed by a degree in computer science or engineering. Familiarity with tools like VMware, Linux/Windows operating systems, cloud platforms (AWS, Azure), and certifications such as CISSP or CompTIA are often required. Strong leadership, project management, and communication skills enable effective team coordination and successful project delivery. These skills are vital for designing robust systems, ensuring reliability, and driving innovation within technical teams.

How does a lead systems engineer typically collaborate with cross-functional teams during large-scale projects?

A Lead Systems Engineer plays a central role in coordinating with cross-functional teams such as software developers, network specialists, project managers, and QA engineers. They facilitate clear communication between technical and non-technical stakeholders, ensuring requirements are well-understood and that implementation stays on track. Lead Systems Engineers often organize and lead design reviews, troubleshoot integration challenges, and mediate technical decisions to align with overall business goals. This collaborative approach is essential for delivering complex system solutions efficiently and effectively.

What is the difference between Lead Systems Engineer vs Systems Engineer?

AspectLead Systems EngineerSystems Engineer
CredentialsBachelor's or higher in Engineering, certifications like INCOSE, PMP often preferredBachelor's degree in Engineering or related field, certifications optional
Work EnvironmentLeading projects, coordinating teams, overseeing system design and integrationSupporting system development, testing, and implementation tasks
Employer & IndustryTechnology, aerospace, defense, manufacturing companiesSimilar industries, often within larger engineering teams
Search & Comparison IntentUnderstanding leadership roles, project management, advanced responsibilitiesEntry to mid-level system design and support roles

The main difference between a Lead Systems Engineer and a Systems Engineer lies in their responsibilities and leadership scope. Lead Systems Engineers oversee project coordination, team management, and system integration, often requiring additional certifications and experience. Systems Engineers focus on supporting system development and testing. Both roles are vital in engineering projects, but the Lead role emphasizes leadership and strategic oversight.

How much does a lead systems engineer make in the US?

A lead systems engineer in the US typically earns between $100,000 and $150,000 annually, with salaries varying based on experience, industry, and location. They often possess advanced technical skills, certifications, and leadership responsibilities that influence compensation.

What are popular job titles related to Lead Systems Engineer jobs in Raleigh, NC?

For Lead Systems Engineer jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Lead Systems Engineer jobs in Raleigh, NC look for?

The top searched job categories for Lead Systems Engineer jobs in Raleigh, NC are:

Infographic showing various Lead Systems Engineer job openings in Raleigh, NC as of August 2026, with employment types broken down into 1% As Needed, 84% Full Time, 10% Part Time, 4% Contract, and 1% Nights. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $193,751 per year, or $93.1 per hour.

Systems Engineer

Raleigh, NC โ€ข On-site

$145K - $175K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 21 days ago


Job description

Senior Systems Engineer – Pharmaceutical Automation
Onsite | $145,000–$175,000 + Full Benefits | Direct Hire

Are you ready to own entire systems instead of just one component?
We're hiring a Senior Systems Engineer to lead the technical integration of highly complex pharmaceutical manufacturing equipment. This is a high-impact role where you'll work directly with a pharmaceutical customer, ensuring advanced aseptic processing systems perform reliably from installation through qualification.
If you enjoy solving complex engineering challenges, working across multiple disciplines, and influencing technical decisions, this is an outstanding opportunity.

What You'll Do
  • Lead system-level engineering for complex pharmaceutical equipment
  • Serve as the primary technical resource for two aseptic filling systems
  • Drive IQ/OQ qualification activities and system readiness
  • Coordinate mechanical, controls, automation, process, validation, and manufacturing teams
  • Translate customer and regulatory requirements into system specifications
  • Lead system integration, design reviews, FMEAs, and technical risk assessments
  • Support FAT, SAT, manufacturing, commissioning, and field activities
  • Partner with customers to resolve technical issues and improve system performance
  • Review technical documentation and engineering specifications
  • Help standardize engineering processes and improve system reliability
What We're Looking For
  • Bachelor's Degree in Mechanical Engineering or related field
  • 8+ years designing or integrating complex pharmaceutical, biotech, or regulated process equipment
Experience with:
  • Systems integration
  • Mechanical & controls engineering
  • GMP/FDA regulated environments
  • FMEA and design reviews
  • Cross-functional technical leadership
Preferred Experience
  • Aseptic fill-finish equipment
  • Lyophilization systems
  • IQ/OQ validation
  • Requirements management / Systems Engineering
  • SolidWorks or Creo
  • Vacuum, thermal, refrigeration, or pressure vessel equipment
Why You'll Love This Role
  • Own complete systems—not just individual components
  • High visibility with customers and engineering leadership
  • Influence system architecture and technical strategy
  • Clear path into Principal Engineer or Technical Leadership roles
  • Support technology used to manufacture life-saving pharmaceutical products
Compensation & Benefits
  • $145,000–$175,000 salary
  • Medical, Dental & Vision Insurance
  • 401(k) with company match
  • Paid Time Off & Holidays
  • Tuition Assistance
  • Career growth with a global automation organization