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Lead Statistician Jobs (NOW HIRING)

Work Schedule Standard (Mon-Fri) Environmental Conditions Office The Lead Statistician works with multi-disciplinary research teams to provide methodological expertise, leadership and strategic ...

Sr Principal Statistician

Palo Alto, CA · On-site

$102K - $125K/yr

The Senior Principal Statistician, Biostatistics will be a lead statistician on individual studies, across related studies, and for integrated summaries and will design and report Phase I to IV ...

Sr Principal Statistician

Palo Alto, CA · On-site +1

$102K - $125K/yr

The Senior Principal Statistician, Biostatistics will be a lead statistician on individual studies, across related studies, and for integrated summaries and will design and report Phase I to IV ...

Sr Principal Statistician

Palo Alto, CA · On-site

$102K - $125K/yr

The Senior Principal Statistician, Biostatistics will be a lead statistician on individual studies, across related studies, and for integrated summaries and will design and report Phase I to IV ...

You independently lead statistical input into clinical trial design, aligning with scientific objectives * You own the development and quality review of statistical study documents * You design and ...

You independently lead statistical input into clinical trial design, aligning with scientific objectives * You own the development and quality review of statistical study documents * You design and ...

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Lead Statistician information

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$40.5K

$83.7K

$117K

How much do lead statistician jobs pay per year?

As of Jun 16, 2026, the average yearly pay for lead statistician in the United States is $83,657.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,000.00 and $116,000.00 per year, depending on experience, location, and employer.

What jobs make $1,000,000 a year?

Lead statisticians in specialized industries such as finance, pharmaceuticals, or technology can earn close to or over $1 million annually, especially with extensive experience, advanced degrees, and leadership roles. High-level executive positions like chief data officers or chief analytics officers may also reach this income level, often supplemented by bonuses and stock options.

What jobs in the US pay 300,000 a year?

Lead statisticians and senior data scientists in the US can earn $300,000 or more annually, especially with extensive experience, advanced skills in statistical software, and leadership responsibilities. High-paying roles often require advanced degrees, such as a master's or Ph.D., and experience in industries like finance, technology, or healthcare.

What jobs pay 500,000 a year in the US?

Lead statisticians in specialized industries such as finance, pharmaceuticals, or technology can reach annual salaries of $500,000 or more, especially with extensive experience, advanced degrees, and leadership roles. High-level executive positions like chief data officers or senior data scientists may also achieve this compensation level, often requiring strong analytical skills, proficiency with statistical software, and strategic oversight.

What does a Lead Statistician do?

A Lead Statistician is responsible for overseeing statistical analyses, designing experiments or studies, and ensuring the integrity and accuracy of data interpretation. They typically manage a team of statisticians, collaborate with other departments, and provide expert guidance on statistical methodologies. Their work is crucial in making data-driven decisions, developing predictive models, and presenting findings to stakeholders. Lead Statisticians often work in sectors like healthcare, pharmaceuticals, finance, or government.

What is the difference between Lead Statistician vs Data Analyst?

AspectLead StatisticianData Analyst
Required CredentialsBachelor's or Master's in Statistics, Mathematics, or related field; often with experience in statistical modelingBachelor's degree in Statistics, Data Science, or related field; often entry-level or mid-level
Work EnvironmentCollaborates with teams on complex statistical projects, often in industries like healthcare, finance, or techAnalyzes data sets to generate reports, dashboards, and insights for business decisions
Employer & Industry UsageUsed in industries requiring advanced statistical expertise and leadership in data projectsCommon across various industries for routine data analysis and reporting

The Lead Statistician typically has advanced education and experience, leading complex projects and teams, while Data Analysts focus on interpreting data and creating reports. Both roles require strong analytical skills, but the Lead Statistician often takes on a strategic and leadership role in data initiatives.

What are the key skills and qualifications needed to thrive as a Lead Statistician, and why are they important?

To thrive as a Lead Statistician, you need a strong background in statistical theory, data analysis, and a relevant degree such as a master's or PhD in statistics, mathematics, or a related field. Expertise in statistical software like SAS, R, or Python, as well as experience with data management and visualization tools, is typically required. Excellent problem-solving, communication, and leadership skills help you guide teams and clearly convey complex findings to non-technical stakeholders. These skills are crucial for ensuring accurate data-driven decision-making and for leading projects that have significant business or research impact.

How does a Lead Statistician typically collaborate with cross-functional teams in an organization?

A Lead Statistician often works closely with professionals from various departments, such as data science, clinical research, product development, and business analytics. They are responsible for translating complex statistical concepts into actionable insights for non-technical stakeholders, guiding study designs, and ensuring data integrity. Effective collaboration involves regular meetings, clear communication, and sometimes mentoring team members on statistical methodologies. This cross-functional teamwork is crucial for aligning statistical strategies with organizational objectives and delivering impactful results.

What is the highest salary for a statistician?

The highest salaries for lead statisticians can exceed $150,000 annually, especially in industries like finance, pharmaceuticals, or technology, where advanced skills and experience are valued. Senior statisticians with specialized expertise, certifications, and proficiency in tools like R or SAS tend to earn the top salaries.
More about Lead Statistician jobs
What states have the most Lead Statistician jobs? States with the most job openings for Lead Statistician jobs include:
Infographic showing various Lead Statistician job openings in the United States as of June 2026, with employment types broken down into 50% As Needed, and 50% Temporary. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $83,657 per year, or $40.2 per hour.
Lead Statistician HEOR

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 22 days ago


Thermo Fisher Scientific rating

7.7

Company rating: 7.7 out of 10

Based on 398 frontline employees who took The Breakroom Quiz

188th of 518 rated manufacturers


Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

The Lead Statistician works with multi-disciplinary research teams to provide methodological expertise, leadership and strategic support at all stages of projects from planning to completion. This individual provides guidance to junior and middle level staff or works independently on projects requiring advanced statistical analysis, interpretation and dissemination of findings.  

Essential Duties and Responsibilities (other duties may be assigned):

Statistical Analysis Plan (SAP) Development  

  • Draft SAPs for projects that require use of advanced statistical methodologies
  • Advise junior and middle level staff on methodology and approach on projects requiring use of standard statistical methodologies
  • Review and approve SAPs projects that require use of standard statistical methodologies

Implementation & Interpretation of Analyses 

  • Project Lead (including execution of analyses) on project requiring the use of advanced statistical methodologies 
  • Provide guidance and advice as needed for junior and mid-level staff on projects requiring use of standard statistical methodologies 

Proposal Writing and Report Preparation 

  • Lead proposal development in familiar project-types or take a supportive role for more complex projects
  • Determine technical approach, review proposal drafts and take responsibility of stats components
  • Get involved in client discussions
  • Obtain significant levels of repeat business from clients
  • May lead technical response to requests for proposals, generates repeat work and amendments 
  • May identify opportunities for new work 
  • May advise and peer-review budget

Communication with internal/external Clients

  • Lead meetings and discussions with clients
  • Act as an escalation point for client concerns related to the project
  • Communicate effectively and proactively with project teams
  • Ability to work with and delegate to junior and mid-level staff, responsible for deliverable quality and integrity
  • Review and support presentations by more junior staff

Consulting Expectations

  • Provide on-the-spot problem-solving and consulting in discussions of results
  • Provide methodological expertise within and outside the team

Methodological Development 

  • Contribute to the conceptualization and development of novel/bespoke solutions to meet client project needs
  • Independently investigate the properties, applicability and advantages/disadvantages of both: 
  • Methodologies developed by Evidera as bespoke solutions to client projects 
  • Newly published methodologies, and seeks senior input when needed
  • May lead the development of parts of tools/macros that improve efficiency of project execution, seeking senior input when needed
  • Provide technical training on the tools developed within HEMA

Scientific Presence

  • Develop and implement the best scientific practices/guidelines, product development/new methods, or deliverable standards
  • Support external thought leadership through publications and workshops
  • Look for opportunities to disseminate knowledge

Financial and managerial

  • Responsible for achieving utilization and proposal and sales target
  • Can supervise and mentor junior and middle level staff, involvement in hiring and development of staff, conducting performance reviews.

In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Education, Professional Skills & Experience:

  • PhD in Biostatistics/Statistics or related field with 4+ years of experience, MSc in Biostatistics/Statistics or related field with 6+ years of experience, or BSc in Biostatistics/Statistics or related field with 8+ years of experience
  • Strong basis in fundamental statistical concepts and methods, and expertise with techniques such as regression analysis (continuous, binary, count data), longitudinal data analysis (mixed effects linear regression), parametric and semi-parametric survival analysis, meta-analysis, indirect treatment comparisons, issues related to missing data, etc.
  • Practical experience in standard statistical applications in health economics such as: 
    o    Standard parametric and semi-parametric survival analyses
    o    Flexible parametric models (spline, piecewise)
    o    ITC methods (Bucher, network meta-analyses [NMA], matching-adjusted indirect comparisons [MAICs], simulated treatment comparisons)
    o    Country-specific utility analyses to inform CEMs
  • Familiarity with complex methods, including:
    o    Projecting incomplete survival data using Bayesian parametric survival models with informative priors
    o    Adjustment for treatment switching (rank preserving structural failure time, inverse probability of censoring weighting, two-stage estimation)
    o    Mixture cure models
    o    multi-state models
    o    Multilevel network meta-regression and fractional polynomial NMA
    o    Surrogacy analyses
  • Strong statistical programming skills with standard software, including R and/or STATA/SAS
  • Ability to communicate analysis plans and results to clients or colleagues who may have limited background in statistics
  • Scientific visibility in terms of authorship of peer-reviewed publications, podium presentations and posters at conferences
  • Leading development and deployment of technology solutions for initiatives involving automation or AI-enablement in statistics and other areas in health economics and market access will be an asset

Thermo Fisher values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive.  Below is listed the working environment/requirements for this role:

  • Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
  • Able to work upright and stationary for typical working hours.
  • Ability to use and learn standard office equipment and technology with proficiency.
  • Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
  • May require travel.  (Recruiter will provide more details.)

Compensation and Benefits

The salary range estimated for this position based in Maryland is $185,000.00–$200,000.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

  • A choice of national medical and dental plans, and a national vision plan, including health incentive programs

  • Employee assistance and family support programs, including commuter benefits and tuition reimbursement

  • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

  • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

  • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards


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