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Lead Statistical Programmer Jobs (NOW HIRING)

ImmunityBio, Inc.

Principal Statistical Programmer

Lead all aspects of the statistical programming activities including efficient programming techniques. * Lead all aspects of creation, validation, traceability, reproducibility, and maintenance of ...

Vrtx

Principal Statistical Programmer

Boston, MA · Remote

$149K - $223K/yr

In addition, the Principal Statistical Programmer is a designated member of clinical sub-team(s) in the role of project lead Statistical Programmer. Key Duties and Responsibilities: * Works regularly ...

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Lead Statistical Programmer information

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How much do lead statistical programmer jobs pay per hour?

As of Jul 2, 2026, the average hourly pay for lead statistical programmer in the United States is $54.96, according to ZipRecruiter salary data. Most workers in this role earn between $43.27 and $68.75 per hour, depending on experience, location, and employer.

What is the difference between Lead Statistical Programmer vs Statistical Programmer?

AspectLead Statistical ProgrammerStatistical Programmer
CredentialsTypically requires a Bachelor's or Master’s in Biostatistics, Statistics, or related field; experience in clinical trialsSame educational background; entry to mid-level experience
Work EnvironmentLeads project teams, manages timelines, and oversees statistical analysisPerforms statistical programming tasks under supervision
Industry UsageUsed across pharmaceutical, biotech, and CROs for leadership rolesCommonly employed in similar settings for technical execution

The main difference between a Lead Statistical Programmer and a Statistical Programmer lies in leadership responsibilities, project management, and oversight. The Lead typically manages teams and ensures project delivery, while the Statistical Programmer focuses on executing statistical analyses under guidance.

What does a Lead Statistical Programmer do?

A Lead Statistical Programmer oversees and manages the programming aspects of clinical trial data analysis. They are responsible for developing, validating, and maintaining statistical programs used to analyze clinical data, typically using software like SAS. In addition to technical programming, they coordinate with statisticians, data managers, and project teams to ensure data integrity and compliance with regulatory standards. Lead Statistical Programmers often mentor junior programmers and play a key role in project planning and timeline management.

What are some common challenges faced by a Lead Statistical Programmer, and how can they be managed?

Lead Statistical Programmers often encounter challenges such as balancing multiple project timelines, ensuring compliance with regulatory standards, and coordinating effectively with cross-functional teams like biostatistics and clinical operations. Managing these challenges requires strong organizational and communication skills, as well as a proactive approach to problem-solving and stakeholder engagement. Regularly updating programming knowledge and fostering collaboration within the team can also help streamline workflows and maintain high-quality deliverables.

What are the key skills and qualifications needed to thrive as a Lead Statistical Programmer, and why are they important?

To thrive as a Lead Statistical Programmer, you need expertise in statistical programming languages like SAS or R, a solid understanding of clinical trial data, and a relevant degree in statistics, mathematics, or a related field. Familiarity with CDISC standards (SDTM, ADaM), regulatory submission processes, and version control systems are essential technical requirements. Strong leadership, communication, and problem-solving skills help in managing teams and collaborating across departments. These skills ensure accurate, compliant data analysis and efficient project delivery in a highly regulated environment.
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Lead Statistical Programmer jobs near you
Infographic showing various Lead Statistical Programmer job openings in the United States as of June 2026, with employment types broken down into 97% Full Time, and 3% Contract. Highlights an 85% Physical, 2% Hybrid, and 13% Remote job distribution, with an average salary of $114,323 per year, or $55 per hour.
Lead Statistical Programmer

Lead Statistical Programmer

Katalyst HealthCares & Life Sciences

San Francisco, CA • On-site

Other

Posted 16 days ago

Job description

Job Title

Responsibilities:

Convert specifications into SAS code to generate datasets and Tables, Listings, and Figures outputs.

Be responsible for overall project delivery, including clinical trial reports and other regulatory submission deliverables.

Create statistical analysis outputs to be used in support of final reports, abstracts, posters, manuscripts, and other clinical publications; support systems to produce electronic regulatory submissions.

Assist in establishing standardized programming procedures and work instructions.

Develop, enhance, evaluate, and validate standardized macros and utility programs to ensure that regulatory requirements are met through validation/compliance activities.

Develop and maintain clinical processing workflow systems.

Assist in the development of client proposal documents.

Provide leadership, project specific training, stakeholder management, external sponsor support, resource management, and project management for the required programming tasks supporting clinical trial activities.

Provide input into and negotiate statistical programming timelines. Ensure that timelines are adhered to and coordinate and lead a statistical programming team to successful completion of a study within given timelines and budgets.

Trained in sponsor SOPs and disseminate knowledge to project team members as appropriate.

Provide input into, and mentor statistical programmers to provide input into documents produced by other functions (e.g., biostatisticians, data managers, medical writers, etc.) records handling (e.g., Chapter 21 of the US Code of Federal Regulation - Part and electronic submission of clinical data to agencies (e.g., e-CTD guidance and CDISC SDTM and ADaM standards).

Assist in updating/writing PROMETRIKA standard operating procedures (SOPs).

Develop tools in SAS® for data analysis and reporting that comply with regulatory requirements.

Develop specifications (e.g., metadata files), annotate CRFs and create SAS® programs for the mapping of raw datasets to CDISC SDTM standards.

Create define.xml files from metadata files for SDTM and ADaM.

Convert data received in other formats to SAS® datasets.

Requirements:

Must have expertise in SAS/BASE, SAS/STAT, and knowledge of SAS/CONNECT, SAS/ACCESS, SAS/MACRO, SAS/GRAPH, SQL, and ODS.

Knowledge of SDTM, ADaM, FDA and ICH guidance.

Understanding of Code of Federal Regulations (CFR) Title 21, Part 11 that covers the management of electronic records and electronic signatures in computer systems.

Good organizational skills across individual projects and managing own and teamwork loads. Ability to organize, manage and complete multiple assignments with challenging timelines independently and effectively.

Consistent experience as a lead statistical programmer on several concurrent projects.

Strong understanding of drug development, including knowledge of interfaces and interdependencies with other functions.

Strong mentoring skills as shown by leadership of projects and if applicable, junior team members.

Excellent analytical skills.

Proven ability to learn new systems and function in an evolving technical environment.

Ability to negotiate and influence to achieve results.

Good presentation skills.

Good business awareness/business development skills (including financial awareness).

Ability to create, maintain and define strategies to improve the efficiency of running a clinical trial.

Work effectively in a quality-focused environment.

Knowledge of other programming languages and database management software packages is a plus.

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About Katalyst Healthcares & Life Sciences

Sourced by ZipRecruiter

Katalyst HealthCares & Life Sciences is a Global Contract Research Organization that provides services in Clinical Research, Manufacturing & Quaity, Regulatory Affairs Areas.. Industries Serving: Pharmaceutical Bio-Pharmaceutical Medical Device Cosmeceuticals & Cosmetics Food & Beverage Clinical Research Scientific Areas Covering: Clinical Research Manufacturing Quality & Validations Regulatory Affairs Intellectual Property Through our in-house team expertise, associates and alliances in the US, Europe and Asia, we can rapidly deliver services, technology, processes and workforce globally, either virtually or integrate into client project space, providing oversight and expertise for individual needs to total end-to-end support for all kinds of clinical trials of Pharma, Biotech, Medical Device and all other scientific products and their manufacturing.

Industry

Scientific research and development services

Company size

51 - 200 Employees

Headquarters location

South Plainfield, NJ, US

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