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Lead Statistical Programmer Jobs (NOW HIRING)

Lead all aspects of statistical programming activities inclusive of creation, validation, traceability, reproducibility, and maintenance of analysis datasets and statistical outputs. * Contribute to ...

Lead statistical programming activities for clinical trials, including the creation, validation, and maintenance of: * CDISC-compliant SDTM datasets * ADaM datasets * Tables, Listings, and Figures ...

Principal Statistical Programmer

Boston, MA · Remote

$149K - $223K/yr

In addition, the Principal Statistical Programmer is a designated member of clinical sub-team(s) in the role of project lead Statistical Programmer. Key Duties and Responsibilities: * Works regularly ...

Acts as the lead statistical programmer. Directs the programming activities of other programming personnel and monitors progress on programming deliverables. Reviews project documentation such as ...

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Lead Statistical Programmer information

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How much do lead statistical programmer jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for lead statistical programmer in the United States is $54.96, according to ZipRecruiter salary data. Most workers in this role earn between $43.27 and $68.75 per hour, depending on experience, location, and employer.

What does a lead statistical programmer do?

A Lead Statistical Programmer oversees and manages the programming aspects of clinical trial data analysis. They are responsible for developing, validating, and maintaining statistical programs used to analyze clinical data, typically using software like SAS. In addition to technical programming, they coordinate with statisticians, data managers, and project teams to ensure data integrity and compliance with regulatory standards. Lead Statistical Programmers often mentor junior programmers and play a key role in project planning and timeline management.

What are the key skills and qualifications needed to thrive as a lead statistical programmer, and why are they important?

To thrive as a Lead Statistical Programmer, you need expertise in statistical programming languages like SAS or R, a solid understanding of clinical trial data, and a relevant degree in statistics, mathematics, or a related field. Familiarity with CDISC standards (SDTM, ADaM), regulatory submission processes, and version control systems are essential technical requirements. Strong leadership, communication, and problem-solving skills help in managing teams and collaborating across departments. These skills ensure accurate, compliant data analysis and efficient project delivery in a highly regulated environment.

What are some common challenges faced by a lead statistical programmer, and how can they be managed?

Lead Statistical Programmers often encounter challenges such as balancing multiple project timelines, ensuring compliance with regulatory standards, and coordinating effectively with cross-functional teams like biostatistics and clinical operations. Managing these challenges requires strong organizational and communication skills, as well as a proactive approach to problem-solving and stakeholder engagement. Regularly updating programming knowledge and fostering collaboration within the team can also help streamline workflows and maintain high-quality deliverables.

What is the difference between Lead Statistical Programmer vs Statistical Programmer?

AspectLead Statistical ProgrammerStatistical Programmer
CredentialsTypically requires a Bachelor's or Master’s in Biostatistics, Statistics, or related field; experience in clinical trialsSame educational background; entry to mid-level experience
Work EnvironmentLeads project teams, manages timelines, and oversees statistical analysisPerforms statistical programming tasks under supervision
Industry UsageUsed across pharmaceutical, biotech, and CROs for leadership rolesCommonly employed in similar settings for technical execution

The main difference between a Lead Statistical Programmer and a Statistical Programmer lies in leadership responsibilities, project management, and oversight. The Lead typically manages teams and ensures project delivery, while the Statistical Programmer focuses on executing statistical analyses under guidance.

How much does a lead statistical programmer make in the US?

A lead statistical programmer in the US typically earns between $100,000 and $130,000 annually, depending on experience, location, and the size of the organization. Senior roles often include additional benefits such as bonuses and health insurance, and proficiency in programming languages like SAS or R is usually required.
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Infographic showing various Lead Statistical Programmer job openings in the United States as of September 2026, with employment types broken down into 88% Full Time, 10% Part Time, and 2% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $114,323 per year, or $55 per hour.

Sr. Statistical Programmer (W2 only)

Sunnyvale, CA • On-site

Technumen
11 - 50 employees

Contractor

Posted 22 days ago


Job description

 
Job Summary (Sr. Statistical Programmer)
Remote (W2 Only)
- Lead statistical programming activities for multiple clinical research projects in pharmaceutical or CRO settings.
- Utilize SAS (and other statistical software) to conduct statistical analyses, develop and validate analysis datasets, tables, listings, and figures.
- Coordinate, supervise, and mentor programming teams, providing coaching and training to junior staff and new hires.
- Serve as a statistical programming lead on internal project teams, managing programming, verification, and documentation tasks.
- Ensure efficient, high-quality, and accurate data reporting and project deliverables, adhering to project timelines and priorities.
- Design, implement, validate, and maintain advanced project reporting applications in collaboration with internal and external stakeholders.
- Represent the department and company in client meetings and presentations, ensuring positive relationships with sponsors and vendors.
- Communicate accurate and timely project status updates to team members and management.
- Contribute to the ongoing improvement of programming processes, methodologies, and best practices.
- Work independently with minimal supervision, demonstrating strong problem-solving and organizational skills.
- Maintain awareness of project tasks and proactively communicate progress, issues, and priorities to management and project teams.
- Requires a Master’s degree in Biostatistics or related field (or equivalent experience) and 8+ years of relevant statistical programming experience.