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As of Sep 10, 2026, the average hourly pay for laboratory information systems engineer in the United States is $47.92, according to ZipRecruiter salary data. Most workers in this role earn between $36.78 and $60.10 per hour, depending on experience, location, and employer.

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Infographic showing various Laboratory Information Systems Engineer job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 73% Full Time, 23% Part Time, and 3% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $99,665 per year, or $47.9 per hour.

Laboratory Information Systems Manager

Dallas, TX

UT Southwestern Medical Center
Hospitals • 10K+ employees

Full-time

Medical, Retirement, PTO

Posted 27 days ago


Key responsibilities

  • Provide strategic direction and operational oversight for all Laboratory Information Systems (LIS) and related applications.

  • Lead the planning, implementation, optimization, and maintenance of laboratory technology solutions supporting Clinical Pathology, Anatomic Pathology, Blood Bank, and outreach laboratory operations.

  • Oversee vendor relationships, contract performance, and service delivery to ensure organizational expectations are met.


UT Southwestern rating

7.9

Company rating: 7.9 out of 10

Based on 152 frontline employees who took The Breakroom Quiz


Job description

WHY UT SOUTHWESTERN?
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career! 
JOB SUMMARY
The Laboratory Information Systems (LIS) Manager is responsible for the strategic leadership, operational management, governance, implementation, and support of laboratory information systems that enable Clinical Pathology, Anatomic Pathology, Blood Bank, and related laboratory services. This leadership role ensures the effective delivery, optimization, and compliance of laboratory technology solutions that support high-quality patient care, operational excellence, and organizational objectives.

The Manager serves as the primary liaison between Information Resources (IR), Laboratory Services, Pathology Leadership, clinical and operational departments, executive stakeholders, and technology vendors. The role requires strong technical expertise, leadership skills, and the ability to manage complex initiatives in a highly regulated healthcare environment.

KEY RESPONSIBILITIES

  • Provide strategic direction and operational oversight for all Laboratory Information Systems (LIS) and related applications.
  • Lead the planning, implementation, optimization, and maintenance of laboratory technology solutions supporting Clinical Pathology, Anatomic Pathology, Blood Bank, and outreach laboratory operations.
  • Establish and oversee governance processes, prioritization frameworks, and project portfolios related to LIS initiatives.
  • Partner with laboratory leadership, pathologists, clinicians, and operational stakeholders to identify technology needs and implement effective solutions.
  • Ensure system reliability, performance, availability, security, and scalability across laboratory applications.
  • Direct and manage complex projects, including system upgrades, implementations, integrations, workflow enhancements, and regulatory initiatives.
  • Oversee vendor relationships, contract performance, and service delivery to ensure organizational expectations are met.
  • Ensure compliance with applicable regulatory and accreditation standards, including CAP, CLIA, FDA, HIPAA, and other healthcare requirements.
  • Develop and maintain policies, procedures, and standards related to laboratory information systems and data management.
  • Lead risk assessment, change management, testing, validation, and issue resolution processes for laboratory technology systems.
  • Monitor key performance indicators and drive continuous improvement initiatives to enhance operational efficiency and user satisfaction.
  • Manage, mentor, and develop LIS team members while fostering a culture of collaboration, accountability, and innovation.

BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:

  • PPO medical plan, available day one at no cost for full-time employee-only coverage
  • 100% coverage for preventive healthcare-no copay
  • Paid Time Off, available day one
  • Retirement Programs through the Teacher Retirement System of Texas (TRS)
  • Paid Parental Leave Benefit
  • Wellness programs
  • Tuition Reimbursement
  • Public Service Loan Forgiveness (PSLF) Qualified Employer
  • Learn more about these and other UTSW employee benefits!


EXPERIENCE AND EDUCATION
Required

  • Education
    High School Diploma or equivalent or 
    Bachelor's Degree with major coursework in computer science, math, information systems, or other related field 
     
  • Experience
    8 years progressively responsible and applicable information technology experience with High School Diploma including 2 years in supervisory or managerial role or 
    6 years progressively responsible information technology experience with Bachelor's Degree including 2 years in supervisory or managerial role 
     

JOB DUTIES

  • Manages Information Resources section, such as Network Services, Software Systems Programming, Computer Training, etc. following university policies and procedures and using effective management, communication, and customer service skills to develop and ensure effective program.
  • Develops, revises, recommends, and interprets policies and procedures for section to ensure all applicable laws and governmental guidelines are followed and that employees are treated in equitable manner.
  • Coordinates various projects and programs for section ensuring all tasks are completed by established deadlines and to ensure that quality customer service is provided for faculty and staff.
  • Assists campus departments in assessing technical requirements that meet needs of their operation.
  • Completes work specific to assigned section using appropriate technologies and communication skills.
  • Supervises group of professional and/or administrative support employees.
  • Performs other duties as assigned.

SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. To the extent this position requires the holder to research, work on, or have access to critical infrastructure as defined in Section 117.001(2) of the Texas Business and Commerce Code, the ability to maintain the security or integrity of the critical infrastructure is a minimum qualification to be hired and to continue to be employed in the position.
EEO
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
 


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