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Internship Downstream Process Development Jobs in Ohio

Ring Container Technologies

Downstream Operator

Sidney, OH · On-site

$15.75 - $18.75/hr

... development. * Provide suggestions for training topics. * Complete any machine and task specific ... Document machine or process changes. * Perform necessary downstream operator checklists. * Maintain ...

thyssenkrupp

Talent Development Internship

Northwood, OH · On-site

$14.25 - $19/hr

Succession Planning A structured process to identify, assess, and develop internal talent for key ... the internship, success means you: * Reliably support Talent Development programs from planning ...

Axogen

Sr. Engineer, Manufacturing/Processing

Vandalia, OH

$97.80K - $126.50K/yr

... Process Development preferably with a regulated medical product. * Proven project leadership ... May include reporting duties for multiple interns and/or engineers * Analysis and recommendations ...

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Internship Downstream Process Development information

What are the key skills and qualifications needed to thrive as an Internship Downstream Process Development, and why are they important?

To thrive in an Internship Downstream Process Development role, a solid background in biotechnology, chemical engineering, or a related field, along with foundational lab skills, is essential. Familiarity with bioprocessing techniques, analytical instruments, and data analysis software is typically required, and experience with GMP environments can be advantageous. Strong problem-solving abilities, attention to detail, and effective communication are important soft skills for collaborating with team members and documenting results. These competencies ensure interns can contribute to optimizing purification processes and maintaining high standards in biopharmaceutical development.

What types of hands-on projects can I expect to work on during an Internship in Downstream Process Development?

As an intern in Downstream Process Development, you will typically assist with projects focused on purification and recovery of biological products, such as proteins or antibodies, from complex mixtures. This often includes tasks like preparing chromatography columns, performing filtration techniques, and conducting sample analysis using methods such as SDS-PAGE or HPLC. You’ll also collaborate closely with experienced scientists and engineers, participate in team meetings to review data, and help troubleshoot process challenges. These experiences provide valuable insight into both laboratory workflows and the broader bioprocess development pipeline.

What is an Internship in Downstream Process Development?

An Internship in Downstream Process Development is a temporary position, typically for students or recent graduates, focused on learning and supporting the processes involved in purifying and formulating biopharmaceutical products after the initial production stage. Interns in this field gain hands-on experience with techniques such as filtration, chromatography, and quality control, and often work within a research and development or manufacturing environment. This internship helps build skills in laboratory methods, data analysis, and process optimization, making it valuable for those interested in careers in biotechnology or pharmaceuticals.

What is the difference between Internship Downstream Process Development vs Downstream Process Technician?

AspectInternship Downstream Process DevelopmentDownstream Process Technician
CredentialsTypically pursuing or holding a degree in biotech, chemistry, or related fieldsUsually requires technical diploma or associate degree in biotech or related areas
Work EnvironmentLaboratory and development settings, focusing on process optimization and experimental workManufacturing floor, operating equipment, and performing process runs
ResponsibilitiesAssisting in process development, data analysis, and protocol documentationExecuting downstream processing steps, equipment setup, and process monitoring

In summary, Internship Downstream Process Development focuses on learning and supporting process optimization in a lab setting, while Downstream Process Technicians handle the hands-on execution of downstream manufacturing processes in production environments.

What cities in Ohio are hiring for Internship Downstream Process Development jobs? Cities in Ohio with the most Internship Downstream Process Development job openings:
Internship Downstream Process Development jobs near you
Infographic showing various Internship Downstream Process Development job openings in Ohio as of May 2026, with employment types broken down into 25% Internship, and 75% Full Time. Highlights an 100% In-person job distribution.
Senior Scientist, Developability & Preformulation

Senior Scientist, Developability & Preformulation

Sarepta Therapeutics, Inc.

Columbus, OH • On-site

$88.40K - $120.70K/yr

Full-time

Posted 6 days ago

Job description

Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
  • Physical and Emotional Wellness
  • Financial Wellness
  • Support for Caregivers

For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
The Importance of the Role
The Early Research and Process Development (ERPD) group is seeking a Senior Scientist with deep expertise in biologics preformulation and developability assessment, with a focus on proteins, antibodies, and antibody-oligonucleotide conjugates (AOCs). This individual will be responsible for assessing the developability of lead molecules through comprehensive evaluations, including biophysical characterization, forced degradation, and short-term, long-term, and in-use stability studies.
The successful candidate will leverage high-throughput formulation tools and workflows to characterize product stability across a broad range of conditions, including process buffers, excipients, concentrations, hold times, and temperatures. In collaboration with Analytical Development, the candidate will help define quality attributes and implement stability-indicating assays appropriate for early-stage programs. The Senior Scientist will also consider route-of-administration factors, such as subcutaneous delivery, during early formulation assessments (e.g., stability and viscosity at high concentrations, potential enabling approaches).
This role requires strong cross-functional engagement, working closely with Upstream and Downstream Process Development, High-Throughput Automation, Nonclinical Manufacturing, and CMC Drug Substance/Drug Product teams to foster a collaborative environment that enables the advancement of robust and scalable manufacturing processes. The Senior Scientist will provide formulation guidance to research, pilot-scale, and commercial-scale manufacturing groups generating scientifically rigorous data packages to inform preclinical and early clinical development and enable downstream CMC strategy for Sarepta's genetic therapy engine.
Sarepta provides a creative culture that invites you to be the best that you can be and is committed to making a difference in patient's lives. Join us at the Genetic Therapy Center of Excellence here in Easton, Ohio.
The Opportunity to Make a Difference
  • Plan and execute formulation experiments to assess and optimize the stability of key intermediates and final products throughout the manufacturing process.
  • Establish developability profiles for candidate molecules, incorporating considerations for route-of-administration.
  • Identify formulation-relevant critical quality attributes for key intermediates and drug product candidates, and guide the development of stability-indicating assays to monitor them.
  • Provide expert guidance on formulation technologies and instrumentation to support informed decision-making.
  • Offer product handling guidance to cross-functional teams.
  • Prepare and review methods, protocols, and technical reports for regulatory submissions or technology transfer.
  • Train and mentor Research Associates in process design, experimental execution, troubleshooting, and data interpretation.

More about You
  • Degree in Biochemistry, Biochemical Engineering, Bioengineering, or Chemical Engineering
    • Ph.D. with ≥ 4 years of biologics formulation experience, or M.S. with ≥ 9 years.
    • Experience with AOCs or antibody-drug conjugates (ADCs) is a plus.
  • Proven technical expertise in protein formulation technologies (e.g., Unchained Labs Big Tuna/Big Kahuna/Junior, Sartorius AMBR Crossflow, Pendotech 5TFF, Repligen KR2i, etc.).
  • Expertise in stability and analytical assays to monitor product quality, including SEC, RP, CE-SDS, cIEF, DLS, DSF, MALS, and mass spectrometry.
  • Experience with high-concentration formulation challenges (e.g., viscosity mitigation strategies, excipient screening, protein-protein interaction understanding)
  • Experience applying Design of Experiments (DoE) principles to formulation development is a plus.
  • Track record of cross-functional collaboration and providing scientifically informed guidance to internal and external teams.
  • Proficiency in statistical or data analysis tools (e.g., JMP, GraphPad, SigmaPlot) is a plus.
  • Prior experience in therapeutic protein discovery or biochemistry research.
  • Excellent written and verbal communication skills.

What Now?
We're always looking for solution-oriented, critical thinkers.
So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
#LI-Onsite
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This position requires work on site at one of Sarepta's facilities in the United States.
The targeted salary range for this position is $118,000 - $147,500 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.

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