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Information Systems Manager Jobs in Raleigh, NC (NOW HIRING)

Guerbet

QA Systems Manager

Raleigh, NC · On-site

$100 - $125/hr

For more information on Guerbet, go to www.guerbet.com and follow Guerbet on Linkedin, Twitter, Instagram and Youtube WHAT WE ARE LOOKING FOR The Quality Systems Manager will be operating in full ...

BioAgilytix

IT Systems Engineer II

Durham, NC · On-site

$80 - $100/hr

The IT Systems Engineer II is responsible for ensuring the stability, integrity, and efficient ... Build, maintain, and manage physical and virtual infrastructure * Proactively manage and ...

GSK

Quality Systems & Data Manager

Zebulon, NC · On-site

Our supply chain is not just core to our operations; it's vital to bringing our innovations to ... Manages implementation of local updates to site quality digital systems including VQMS, MERP ...

ACA Group

Manager, IT Security

Durham, NC · Hybrid

In the role of IT Security Manager, you will lead the security team and be responsible for ... Lead the development and execution of the security strategy for ACA's technology systems * Manage ...

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All JobsInformation Systems JobsInformation Systems Manager JobsInformation Systems Manager Jobs in Raleigh, NC

Information Systems Manager information

See Raleigh, NC salary details

$42.8K

$102.8K

$145.3K

How much do information systems manager jobs pay per year?

As of Sep 9, 2026, the average yearly pay for information systems manager in Raleigh, NC is $102,824.00, according to ZipRecruiter salary data. Most workers in this role earn between $77,800.00 and $125,900.00 per year, depending on experience, location, and employer.

What does an information systems manager do?

An information systems manager is an IT specialist who oversees the implementation and maintenance of an organization’s technology. Your duties are to manage a team of IT workers to install or upgrade hardware and software, develop security protocols and practices, and train other workers in how to use the technology. You often provide reports to upper management about the health and safety of the IT systems and make recommendations for improvement. Some information systems managers specialize in a specific area of IT, such as security or networks, while others oversee the operations of the entire system.

What are the key skills and qualifications needed to thrive as an information systems manager, and why are they important?

To thrive as an Information Systems Manager, you need a strong background in IT infrastructure, systems analysis, and project management, often supported by a degree in computer science or information systems. Familiarity with enterprise resource planning (ERP) systems, network management tools, and certifications such as PMP or CISSP is typically required. Strong leadership, problem-solving abilities, and effective communication are essential soft skills for managing teams and projects. These skills are crucial for ensuring reliable IT operations, securing data, and aligning technology with business objectives.

What are some common challenges information systems managers face when balancing security needs with user accessibility?

Information Systems Managers often navigate the challenge of implementing robust security protocols while ensuring that users have seamless access to the systems and data they need. Striking this balance can involve managing access controls, monitoring for cyber threats, and maintaining compliance with regulations, all without impeding productivity. Effective communication with stakeholders and ongoing user training are essential to address these challenges, as is staying updated on emerging threats and security technologies. Collaborating closely with IT teams and business units helps create solutions that meet both security and operational needs.

What is the difference between Information Systems Manager vs Network Administrator?

AspectInformation Systems ManagerNetwork Administrator
CredentialsBachelor's degree in IT, Computer Science, or related field; often certifications like PMP, CISSPBachelor's degree in IT, Computer Science, or related field; certifications like Cisco CCNA, CompTIA Network+
Work EnvironmentOversees entire IT infrastructure, manages teams, strategic planningMaintains and supports network hardware/software, troubleshooting network issues
Employer & Industry UsageUsed across industries for IT leadership rolesCommon in organizations with complex network needs, including corporate and government sectors

While both roles require IT knowledge and certifications, the Information Systems Manager focuses on strategic management and overseeing IT systems, whereas the Network Administrator specializes in maintaining and troubleshooting network infrastructure. The roles often collaborate but differ in scope and responsibilities.

What is the average salary of an information systems manager?

The average salary of an information systems manager typically ranges from $90,000 to $150,000 annually, depending on experience, location, and industry. Professionals with certifications like PMP or CISSP and strong leadership skills tend to earn higher salaries.
More about Information Systems Manager jobs

What are the most commonly searched types of Information Systems jobs in Raleigh, NC?

The most popular types of Information Systems jobs in Raleigh, NC are:

What are popular job titles related to Information Systems Manager jobs in Raleigh, NC?

For Information Systems Manager jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Information Systems Manager jobs in Raleigh, NC look for?

The top searched job categories for Information Systems Manager jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Information Systems Manager jobs?

Cities near Raleigh, NC with the most Information Systems Manager job openings:

Information Systems Manager jobs near you
Infographic showing various Information Systems Manager job openings in Raleigh, NC as of August 2026, with employment types broken down into 1% As Needed, 77% Full Time, 19% Part Time, and 3% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $93,398 per year, or $44.9 per hour.

RIM Operations Systems Manager, Raleigh, NC

Raleigh, NC • Hybrid

UCB
Finance and Insurance • 1 - 5K employees
Learn more about UCBexternal

Full-time

Posted 12 days ago

Job description

Make your mark for patients

We are looking for a RIM Operations Systems Manager, curious, structured, and people-focused, to join us in our Regulatory Community Excellence team, based in our Raleigh, NC location.

About the role

You will advance our Regulatory Information Management (RIM) systems, supporting their high-impact performance and innovation, with an emphasis on Veeva Vault RIM.

You are going to support RIM system users and turn business needs into system changes, support releases, and make sure our tools stay compliant and easy to use. You will also help bring in smarter ways of working, including automation and AI-enabled features.

Who you'll work with

You will work with system owners and the RIM Operations team. You will partner with IT, Quality, and stakeholders across the business to improve how regulatory work is supported by data and technology, while driving user adoption and compliance with RIM systems.

What you'll do

  • You will support and guide system users by contributing to user guidance and training, managing a shared mailbox, and focusing on change management to help increase adoption and satisfaction.
  • You will support system ownership activities for the RIM toolset, including Veeva Vault RIM, system integrations, authoring tools, and reporting interfaces
  • You will coordinate configuration changes, enhancements, testing, and releases to keep the platform stable and fit for purpose.
  • You will turn operational needs into clear requirements and user stories that teams can build and validate.
  • You will help improve workflows, prepare user acceptance testing, and confirm changes meet quality and compliance needs.
  • You will support data and access governance, validation documents, and audit materials to meet GxP expectations.

Interested? For this position you'll need the following education, experience and skills:

You will bring several years' experience in Regulatory Operations, RIM, or regulatory systems management in a regulated environment and across global regions.

You will have hands-on experience with Veeva Vault RIM (required).

You will have experience with configuration, releases, testing, and deployments in enterprise systems.

You will understand data integrity and computerized system validation in GxP environments.

You will be experienced working with integrations, vendors, and cross-functional partners to solve issues and improve service levels.

You will be comfortable providing end-user support and providing process and system expertise to guide users to compliant use of regulatory systems.

Internal applicants should be in their current job for at least 12 months, must meet performance standards and are not on formal corrective/disciplinary process (PIP), warning, final warning, or compliance warning letters within the last 12 months. Please inform your Manager or your Talent Partner before applying to any internal job opportunities.

Unlessexplicitlystated in the description, this role is hybrid with 40% of your time spent in the office,regardlessof your current contractual agreement. If your current working arrangements differ, please contact your Talent Partner to discuss before submitting your application.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable federal, state, or local law. UCB invites you to voluntarily self-identify during the application process. Provision of self-identification information is entirely voluntary and a decision to provide or not provide such information will not have any effect on your application for employment, your employment with UCB, or otherwise subject you to any adverse treatment. Any information you provide will be considered confidential and will be kept separate from your application and/or personnel file and will only be used in accordance with applicable laws, orders, and regulations.


Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on US-Reasonable_Accommodation@ucb.com for application to US based roles. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.

Requisition ID:93971

Recruiter:Kelly Dickinson

Hiring Manager:Kirsten Moe

Talent Partner:Bianca Hinshaw

Job Level:SA I

Please consult HRAnswers for more information on job levels.

Employment Type: OTHER

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