ZipRecruiter

Log In

1

Genomic Variant Scientist Jobs (NOW HIRING)

BillionToOne

Senior Scientist

Menlo Park, CA · On-site +1

$251K/yr

This role sits at the intersection of AI, genomics, oncology research, and clinical data science ... variant interpretation, and clinical trial or guideline tracking-while helping lay the foundation ...

BillionToOne

Senior Scientist

Menlo Park, CA · On-site

$107K - $147K/yr

A Rare Opportunity to Shape the Future of Genomics Join a team of brilliant, passionate innovators ... variant interpretation, and clinical trial or guideline tracking-while helping lay the foundation ...

BillionToOne

Senior Scientist, Oncology

Menlo Park, CA · On-site

$107K - $147K/yr

A Rare Opportunity to Shape the Future of Genomics Join a team of brilliant, passionate innovators ... variant interpretation, and clinical trial or guideline tracking-while helping lay the foundation ...

BillionToOne

Senior Scientist, Oncology

Menlo Park, CA · On-site +1

$251K/yr

This role sits at the intersection of AI, genomics, oncology research, and clinical data science ... variant interpretation, and clinical trial or guideline tracking-while helping lay the foundation ...

next page

Showing results 1-20

All JobsGenomic Variant Scientist Jobs

Genomic Variant Scientist information

See salary details

$36.5K

$79.4K

$137.5K

How much do genomic variant scientist jobs pay per year?

As of Jun 9, 2026, the average yearly pay for genomic variant scientist in the United States is $79,408.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,500.00 and $93,000.00 per year, depending on experience, location, and employer.

What are the common challenges faced by Genomic Variant Scientists when interpreting complex genetic data, and how are these addressed in a typical work environment?

Genomic Variant Scientists often encounter challenges such as distinguishing pathogenic variants from benign ones, managing large datasets, and keeping up with the rapidly evolving scientific literature. In most work environments, these challenges are addressed through collaborative teamwork with bioinformaticians, clinical geneticists, and laboratory technicians. Access to advanced computational tools, regular case discussions, and ongoing professional development opportunities help scientists stay updated and improve the accuracy of variant interpretation. This collaborative and resource-rich environment enables Genomic Variant Scientists to tackle complex cases and contribute effectively to patient care or research outcomes.

What are the key skills and qualifications needed to thrive as a Genomic Variant Scientist, and why are they important?

To thrive as a Genomic Variant Scientist, a deep understanding of genetics, genomics, and molecular biology is essential, usually supported by an advanced degree in a life science field. Familiarity with next-generation sequencing (NGS) technologies, variant annotation tools, and bioinformatics software such as GATK and VEP is typically required. Strong analytical thinking, attention to detail, and effective communication skills help in interpreting complex data and collaborating with multidisciplinary teams. These skills ensure accurate variant interpretation, enabling meaningful clinical or research insights that drive advances in precision medicine.

What does a Genomic Variant Scientist do?

A Genomic Variant Scientist specializes in identifying, analyzing, and interpreting genetic variations within DNA sequences. They use advanced bioinformatics tools and laboratory techniques to detect changes in genes that may be linked to diseases, traits, or drug responses. Their work is crucial in fields like personalized medicine, genetic research, and clinical diagnostics, helping to translate genomic data into actionable insights for patient care or scientific discovery.

What is the difference between Genomic Variant Scientist vs Genetic Data Analyst?

AspectGenomic Variant ScientistGenetic Data Analyst
Required CredentialsBachelor's or Master's in Genetics, Genomics, or related field; experience with genomic dataBachelor's or Master's in Genetics, Bioinformatics, or related field; proficiency in data analysis tools
Work EnvironmentResearch labs, biotech companies, academic institutionsHealthcare settings, research institutions, biotech firms
Industry UsageGenomics research, variant interpretation, experimental analysisData interpretation, report generation, clinical data analysis

While both roles involve working with genetic data, Genomic Variant Scientists focus on identifying and interpreting genetic variants through laboratory and computational methods. Genetic Data Analysts primarily analyze and interpret genetic data sets to support research or clinical decisions. The roles often overlap in skills and environment but differ in their core responsibilities and focus areas.

More about Genomic Variant Scientist jobs
What cities are hiring for Genomic Variant Scientist jobs? Cities with the most Genomic Variant Scientist job openings:
What states have the most Genomic Variant Scientist jobs? States with the most job openings for Genomic Variant Scientist jobs include:
What job categories do people searching Genomic Variant Scientist jobs look for? The top searched job categories for Genomic Variant Scientist jobs are:
Genomic Variant Scientist jobs near you
Infographic showing various Genomic Variant Scientist job openings in the United States as of May 2026, with employment types broken down into 90% Full Time, and 10% Part Time. Highlights an 85% In-person, and 15% Remote job distribution, with an average salary of $79,408 per year, or $38.2 per hour.

Sr. Clinical Bioinformatics Scientist

myDNA, Inc.

Houston, TX • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 18 days ago

Job description

OUR PURPOSE
Our mission is to build a healthier and more connected world with precision health and genealogy services. We empower individuals with actionable insights into their genetic makeup, fostering a deeper understanding of their ancestry, health, and wellness. By integrating the experience of Gene by Gene Laboratory Services, FamilyTreeDNA genealogy, and myDNA reporting services, we strive to deliver cutting-edge genetic testing and personalized solutions that inspire informed decisions and enhance quality of life. Our team is dedicated to advancing the field of genomics through innovation, research, and a commitment to excellence.
OUR VALUES
All employees are expected to demonstrate our values of Innovate, One Team, and Integrity when carrying out the accountabilities and responsibilities of their role. This how we show up every day for ourselves, our colleagues and our customers and strategic partners to deliver our vision and strategic goals.
POSITION OVERVIEW
Gene By Gene is seeking a senior-level Clinical Bioinformatics Scientist to develop and maintain high-throughput genomic pipelines in a regulated clinical laboratory environment (CLIA/CAP). The position will involve transforming raw next generation sequencing (NGS) data into actionable clinical insights, ensuring the accuracy, scalability, and security of diagnostic assays.
ACCOUNTABILITIES AND RESPONSIBILITIES
  • Pipeline Development: Design, optimize, and validate new automated bioinformatics workflows for genetic variant calling, including the following:
    • Using or developing software to receive, process, and analyze genetic data.
    • Assessing software and programs for suitability to achieve desired analysis goals
    • Determination of appropriate analysis parameters and thresholds for identification and evaluation of genetic markers of interest
    • Designing defined analysis protocols within the software for routine use by other data analysts, including pre-set filters and settings
    • Validation of developed protocols to demonstrate accurate generation and reporting of results
    • Writing or revising code to aid in the processing or analysis of samples though the lab
  • Variant Analysis: Use developed analysis pipelines to implement algorithms for detection of SNV's, Indels, CNV's, and structural variants from genetic data.
  • Clinical Validation: Complete and document the analytical validation of bioinformatics tools to meet regulatory requirements for clinical use, including the analytical validity of risk models to satisfy CLIA / CAP / ACMG requirements.
  • Data Management: Oversee large-scale genomic datasets, ensuring data integrity, security, and HIPAA compliance
  • Quality Control: Establish automated QC metrics to monitor run performance and data integrity.
  • Collaboration: Work with laboratory directors, clinical geneticists, the research and development team, and IT professionals to integrate and implement bioinformatics tools to fulfill client reporting requirements.
  • Report Generation: Work with laboratory directors, clinical geneticists, and IT professionals to create clinically validated reporting pipelines for genetic data interpretation, including Monogenic and Polygenic Risk Scores, Pharmagogenomics (PGx) interpretation, and Carrier Screening.
  • Troubleshooting: Resolve technical issues in production pipelines to prevent delays in client report generation and delivery.

POSITION REQUIREMENTS
  • Doctoral Degree in Bioinformatics, Computational Biology, Statistical Genetics, or a related field with 5+ years post-graduate experience.
  • Understanding of general molecular biology and genetic laboratory procedures.
  • Ability to apply theoretical knowledge of genetics towards interpretation of genetic data to generate clinical reports.
  • Expertise with bioinformatics principles and ability to apply this knowledge towards implementation of genetic analysis programs and clinical report generation pipelines.
  • Knowledge of clinical laboratory regulatory requirements for clinical diagnostics and reporting, including familiarity with HIPAA, CLIA, NYSDOH CLEP standards, and ACMG variant interpretation classifications.
  • Understanding of population genetics and statistical modeling to account for ancestry, ethnicity, and environmental factors in the calculation of risk scores for complex traits.
  • Understanding of genetic imputation and haplotype phasing determination, and ability to ensure that imputed data meets strict quality control thresholds for clinical use.
  • Familiarity with machine learning for genomic functional prediction and pattern recognition.
  • Familiarity with multiple NGS instrumentation platforms and their file formats (eg. Illumina, Ultima Genomics, Complete Genomics, Oxford Nanopore, etc.) and ability to create platform agnostic analysis pipelines, adaptable to various platforms.
  • Expertise or Familiarity with the following (or similar) environments, databases, coding languages, software suites, data analysis tools, etc.:
    • Command Line, Python, R, Java, shell scripting (Bash)
    • SQL and database administration
    • Strong command of Linux/Unix environments
    • Cloud computing (AWS, Google Cloud, or Azure)
    • Containerization (Docker, Kubernetes)
    • Software version control tools (Git)
    • NGS analysis tools and variant annotation databases: FastQC, Samtools, Bamtools, VCFTools, BWA, GATK, ClinVar, gnomAD
    • Bioinformatics tools for analysis of large-scale genomic data (PLINK, Eagle2, Beagle, etc.)
    • Workflow managers (Nextflow or similar)
    • Genetic databases and reference standard repositories (NCBI GenBank, RefSeq, ENSEMBL, Genome Reference Consortium etc.)
    • Global and population-specific genetic reference panels (TOPMed, 1000 Genomes Project, Haplotype Reference Consortium, GenomeAsia, African Genome Resource, etc.)

WHY JOIN US
At Gene by Gene, you'll join a mission-driven team advancing the science of genetics and discovery. You'll have the opportunity to shape meaningful campaigns, tell compelling brand stories, and collaborate with talented professionals who share your passion for creativity, curiosity, and impact.
COMPREHENSIVE BENEFITS
  • Medical & Health Savings: Choice of 3 medical tiers generously sponsored by the company, with a monthly $50-$100 employer HSA contribution based on plan type and dependent level.
  • 100% Covered Dental & Vision: No premium costs for employees or dependents.
  • 401(k) Matching: Generous 50% company match up to 6% of annual base salary.
  • Diverse PTO Framework: Structured time off incorporating vacation, sick leave, mental health days, personal days, company holidays, and a flexible floating holiday.
  • Income Protection & Family Leave: Full company sponsorship of Short-Term and Long-Term Disability (STD/LTD) alongside Paid Family Leave offerings.

Apply