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Genomic Variant Scientist Jobs (NOW HIRING)

Astrix Inc

Associate AI Scientist

South San Francisco, CA · On-site

$30 - $38/hr

Job Title: Associate AI Scientist (Contract) Location: South San Francisco, CA (Onsite with ... The work supports research efforts in genomics, regulatory biology, and variant interpretation. Key ...

Tuskegee University

Develop and implement bioinformatics pipelines for variant calling, structural variant detection ... Collaborate with wet-lab scientists to integrate genomic data with experimental results.

Baylor Genetics

Senior R&D Scientist, Algorithm Developer

$93K - $127K/yr

The Senior Scientist will also lead the design and optimization of targeted NGS panels for existing ... Experience with machine learning models for variant classification * Knowledge of clinical genomics ...

Tempus

Staff, Software Engineer

California, MO · On-site

$164K - $246K/yr

Design and own data models, APIs, and search/query strategies that make large-scale genomic variant data fast and precise to filter, faceted, and retrieve at scale. * Partner directly with scientific ...

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Genomic Variant Scientist information

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$36.5K

$79.4K

$137.5K

How much do genomic variant scientist jobs pay per year?

As of Sep 9, 2026, the average yearly pay for genomic variant scientist in the United States is $79,408.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,500.00 and $93,000.00 per year, depending on experience, location, and employer.

What does a genomic variant scientist do?

A Genomic Variant Scientist specializes in identifying, analyzing, and interpreting genetic variations within DNA sequences. They use advanced bioinformatics tools and laboratory techniques to detect changes in genes that may be linked to diseases, traits, or drug responses. Their work is crucial in fields like personalized medicine, genetic research, and clinical diagnostics, helping to translate genomic data into actionable insights for patient care or scientific discovery.

What are the key skills and qualifications needed to thrive as a genomic variant scientist?

To thrive as a Genomic Variant Scientist, a deep understanding of genetics, genomics, and molecular biology is essential, usually supported by an advanced degree in a life science field. Familiarity with next-generation sequencing (NGS) technologies, variant annotation tools, and bioinformatics software such as GATK and VEP is typically required. Strong analytical thinking, attention to detail, and effective communication skills help in interpreting complex data and collaborating with multidisciplinary teams. These skills ensure accurate variant interpretation, enabling meaningful clinical or research insights that drive advances in precision medicine.

What are the common challenges faced by genomic variant scientists when interpreting complex genetic data, and how are these addressed in a typical work environment?

Genomic Variant Scientists often encounter challenges such as distinguishing pathogenic variants from benign ones, managing large datasets, and keeping up with the rapidly evolving scientific literature. In most work environments, these challenges are addressed through collaborative teamwork with bioinformaticians, clinical geneticists, and laboratory technicians. Access to advanced computational tools, regular case discussions, and ongoing professional development opportunities help scientists stay updated and improve the accuracy of variant interpretation. This collaborative and resource-rich environment enables Genomic Variant Scientists to tackle complex cases and contribute effectively to patient care or research outcomes.

What is the difference between Genomic Variant Scientist vs Genetic Data Analyst?

AspectGenomic Variant ScientistGenetic Data Analyst
Required CredentialsBachelor's or Master's in Genetics, Genomics, or related field; experience with genomic dataBachelor's or Master's in Genetics, Bioinformatics, or related field; proficiency in data analysis tools
Work EnvironmentResearch labs, biotech companies, academic institutionsHealthcare settings, research institutions, biotech firms
Industry UsageGenomics research, variant interpretation, experimental analysisData interpretation, report generation, clinical data analysis

While both roles involve working with genetic data, Genomic Variant Scientists focus on identifying and interpreting genetic variants through laboratory and computational methods. Genetic Data Analysts primarily analyze and interpret genetic data sets to support research or clinical decisions. The roles often overlap in skills and environment but differ in their core responsibilities and focus areas.

More about Genomic Variant Scientist jobs

What cities are hiring for Genomic Variant Scientist jobs?

Cities with the most Genomic Variant Scientist job openings:

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What states have the most Genomic Variant Scientist jobs?

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What are popular job titles related to Genomic Variant Scientist jobs?

For Genomic Variant Scientist jobs, the most frequently searched job titles are:

Genomic Variant Scientist jobs near you
Infographic showing various Genomic Variant Scientist job openings in the United States as of September 2026, with employment types broken down into 86% Full Time, and 14% Contract. Highlights an 82% In-person, and 18% Remote job distribution, with an average salary of $79,408 per year, or $38.2 per hour.

Clinical Genomic Specialist I

Cambridge, MA • On-site

Broad Institute
1 - 5K employees
Learn more about Broad Instituteexternal

$58K - $76K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 8 days ago

Key responsibilities

  • Support ClinGen curation activities by researching the significance of variants and genes, and classifying variant- and gene-disease associations.

  • Assist in sharing curated genomic knowledge with the community, support data submission to ClinVar, and help develop software tools for variant and gene curation.

  • Support other genetic and genomic research projects at the Broad Institute.

Job description

General information
Location
Cambridge, MA
Ref #
44583
Job Family
Research
Date published
08/31/2026
Time Type
Full time
Pay Range
$58,000.00/yr - $76,667.00/yr
Description & Requirements
We are seeking motivated individuals to work in a cutting-edge environment to serve as a clinical genomics coordinator for the Clinical Genome Resource (ClinGen). ClinGen is an NIH-funded program that is building authoritative resources to define the clinical relevance of genes and variants for use in precision medicine and research (https://www.clinicalgenome.org/). This position would begin with training within our variant and gene-curation team which supports variant classification and gene-disease validity assessment followed by supporting an array of ClinGen disease-specific Expert Panel activities and affiliated projects within ClinGen.
PRINCIPAL DUTIES AND RESPONSIBILITIES
Support ClinGen curation activities
  • Research the significance of variants and genes through literature and data review
  • Classify variant- and gene-disease associations
  • Support research projects that require curation of genomic knowledge
  • Support the ClinGen's mission to provide better access to genomic data
  • Support the sharing of curated knowledge with the community
  • Assist laboratories with data submission to ClinVar (www.ncbi.nlm.nih.gov/clinvar)
  • Assist in the development of software tools for supporting variant and gene curation
  • Assist in resolving variant interpretation differences between ClinVar submitters
  • Assist Clinical Domain WGs in supporting gene and variant curation programs
  • Support the writing of ClinGen research publications
  • Support other projects related to genetic and genomic research at the Broad

In addition, the applicant should possess excellent organizational skills and the ability to interact effectively with a local team at the Broad Institute and an international network of laboratories, disease experts and data sources and balance and manage multiple tasks and projects independently. The ClinGen team is part of the Translational Genomics Group (TGG, https://the-tgg.org/). The TGG supports the use of genomics in medicine, by focusing on community-centered projects that promote collaboration, data sharing and open science. The TGG is led by Heidi Rehm and consists of high-impact projects such as the Center for Mendelian Genomics co-led by Anne O'Donnell-Luria and the gnomAD project co-led by Mark Daly.
Start date: ASAP or by August 2026 with a minimum of a two-year commitment
Qualifications: BA or BS degree in the sciences with 2+ years as a Clinical Genomics Assistant or related experience
Job locations: 300 Binney, Cambridge, MA
This role will be a hybrid position with an expectation of a minimum of 2-3 days physically in the office.
The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.

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