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Full Time Trial Master File Jobs (NOW HIRING)

Liquidia Corporation

TMF Associate

$34.25 - $46.75/hr

Job Summary The TMF Associate supports the successful execution of clinical trials by ensuring the Trial Master File (TMF) is complete, inspection ready, and maintained in accordance with regulatory ...

CPC

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Clinical Trials Project Manager II - remote

Raleigh, NC · Remote

$72K - $95K/yr

Provide Head of Trial Master File scope of services to enable him/her to establish and maintain Trial Master Files (TMFs) and project document files, both electronic and paper. * Adhere to local ...

CEDENT

Study Start-Up Manager

Wilmington, DE · On-site

Ensure the timely submission of documents to regulatory authorities and maintain the trial master file (eTMF). Qualifications * Minimum 3 years of experience in Clinical Study Start-Up (full-time)

City Therapeutics

Sr. Clinical Trial Manager

Cambridge, MA · On-site

$164K - $185K/yr

Please note this is a full-time onsite opportunity Responsibilities: * Lead cross-functional teams ... Oversee CRO management of the Trial Master File (TMF), ensuring completeness and quality. Ensure ...

Prometrika LLC

Clinical Trial Manager

Cambridge, MA · On-site

$140K - $168K/yr

Manage the operational aspects of clinical trials (e.g., study management, site monitoring and management, trial master file (TMF) oversight,) * Coordinate and support regulatory submissions and ...

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How much do full time trial master file jobs pay per hour?

As of Jun 20, 2026, the average hourly pay for full time trial master file in the United States is $17.74, according to ZipRecruiter salary data. Most workers in this role earn between $15.87 and $18.99 per hour, depending on experience, location, and employer.

What is the difference between Full Time Trial Master File vs Clinical Trial Associate?

AspectFull Time Trial Master FileClinical Trial Associate
CredentialsRegulatory knowledge, document management experienceClinical research training, basic regulatory understanding
Work EnvironmentRegulatory departments, sponsor officesClinical sites, research organizations
Industry UsagePharmaceutical, biotech, CROsClinical research, trial coordination

The Full Time Trial Master File primarily manages regulatory documents and ensures compliance, while the Clinical Trial Associate supports trial operations and site management. Both roles are essential in clinical research but differ in focus and responsibilities.

What cities are hiring for Full Time Trial Master File jobs? Cities with the most Full Time Trial Master File job openings:
What are the most commonly searched types of Trial Master File jobs? The most popular types of Trial Master File jobs are:
Full Time Trial Master File jobs near you
TMF Associate

TMF Associate

Liquidia Corporation

Remote

$34.25 - $46.75/hr

Full-time

Medical, Dental, Vision, Retirement

Posted 11 days ago

Job description

Job Description
Liquidia is deeply passionate and committed to the discovery, engineering, and development required to bring novel therapies to patients who need them most, and to the healthcare providers who care for them. Our current drive is toward improving the treatment of pulmonary hypertension (PH). We will continue to combine our proprietary, innovative PRINT® Technology with new and established medications, offering the potential for both better precision and improved clinical outcomes. Our team members include some of the industry's top scientists, clinicians, business strategists, engineers, and pharmaceutical executives. We work together to help people lead longer, healthier, and happier lives.
Job Summary
The TMF Associate supports the successful execution of clinical trials by ensuring the Trial Master File (TMF) is complete, inspection ready, and maintained in accordance with regulatory requirements, internal SOPs, and study timelines. This role collaborates closely with Clinical Operations, Quality, Regulatory, and CRO partners to drive high quality documentation practices across the study lifecycle. The TMF associate reports to the TMF specialist.
Job Requirements
Education and Experience
• Bachelor's degree in life sciences, healthcare, or related field (or equivalent experience) is preferred.
• 1-3 years of experience in clinical research, preferably with direct TMF or document management responsibilities.
• Familiarity with ICH GCP, TMF Reference Model, and regulatory documentation requirements.
• Experience working with CROs or in a sponsor environment.
Knowledge, Skills, and Abilities
• Understanding of clinical trial lifecycle and essential document requirements.
• Strong organizational skills with the ability to manage multiple priorities and deadlines.
• High attention to detail and commitment to documentation accuracy.
• Proficiency with TMF systems (e.g., Veeva Vault, Wingspan, Trial Interactive, etc.) and Microsoft Office tools.
• Excellent communication and collaboration skills.
• Ability to work independently while contributing to a team-oriented environment.
Job Responsibilities
TMF Management & Quality
  • Maintain the electronic Trial Master File (eTMF) in compliance with ICH GCP, regulatory guidelines, and company SOPs.
  • Perform routine TMF health checks, quality reviews, reconciliation, and completeness reviews to ensure ongoing inspection readiness.
  • Upload, index, and QC essential documents with a high degree of accuracy and attention to detail.
  • Support TMF health assessments, metrics reporting, and remediation activities.
  • Track missing, overdue, or non-compliant documents and follow up with internal teams and CRO partners to ensure timely resolution.

Cross Function Collaboration
  • Partner with Clinical Trial Managers, CRAs, and CRO counterparts to ensure consistent document flow and alignment with the TMF Reference Model.
  • Assist in TMF training for study team members and vendors, reinforcing documentation expectations and best practices.
  • Participate in study team meetings to provide TMF status updates and identify risks or gaps.

Audit & Inspection Support
  • Prepare TMF documentation for internal audits, sponsor audits, and regulatory inspections.
  • Support audit findings resolution and corrective/preventive action (CAPA) implementation related to TMF processes.
  • Ensure all TMF activities are fully traceable and compliant with inspection standards.

Process Improvement
  • Contribute to the development and refinement of TMF processes, templates, and SOPs.
  • Identify opportunities to streamline workflows and enhance documentation quality across studies.
  • Support system enhancements or migrations for eTMF platforms.

Job Benefits
Liquidia offers a competitive compensation package as well as a comprehensive benefits package that includes Medical, Dental, Vision, STD, LTD, 401(k) Savings Retirement Plan, ESPP, and more!
Liquidia is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. Reasonable accommodation may be made to enable qualified individuals with disabilities to perform the essential functions of this position.
Recruiting Agencies, Please Note:
Liquidia will not accept unsolicited assistance from recruiting/search agencies for this employment opportunity. Please, no phone calls or emails. All resumes submitted by recruiting or search agencies to any employee at Liquidia via email, the Internet or in any form and/or method without a valid written search/recruitment agreement in place for this position will be deemed the sole property of Liquidia. No fee will be paid in the event the candidate is hired by Liquidia as a result of the referral or through other means.

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