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How much do fractionation technician jobs pay per year?

As of Aug 17, 2026, the average yearly pay for fractionation technician in the United States is $54,605.00, according to ZipRecruiter salary data. Most workers in this role earn between $40,500.00 and $60,500.00 per year, depending on experience, location, and employer.

What is a fractionation technician?

Fractionation Technicians are professionals who operate and monitor equipment used in the process of separating chemical substances, typically in industries like pharmaceuticals, biotechnology, or petroleum refining. They ensure that raw materials are properly separated into their component parts through processes such as distillation or filtration. Their responsibilities include setting up and maintaining machinery, collecting samples, analyzing output, and adhering to safety and quality standards. Fractionation Technicians play a vital role in ensuring product purity and meeting production targets.

What are the key skills and qualifications needed to thrive as a fractionation technician?

To thrive as a Fractionation Technician, you need a solid understanding of chemical processes, attention to detail, and a high school diploma or an associate degree in a science-related field. Familiarity with laboratory equipment, process control systems, and safety protocols is typically required, and certifications in chemical handling or safety can be advantageous. Strong problem-solving skills, teamwork, and effective communication help technicians work efficiently and safely in controlled environments. These skills and qualifications are critical for maintaining product quality, ensuring safety, and supporting the smooth operation of fractionation processes.

What are some typical challenges a fractionation technician might face during their shifts?

Fractionation Technicians often encounter challenges such as maintaining strict safety and quality standards while monitoring complex equipment and processes. They must quickly troubleshoot issues like fluctuations in temperature or pressure, which can impact product purity. Additionally, balancing multiple tasks during busy shifts and coordinating effectively with other team members and departments is crucial. Adapting to shift work schedules and staying updated with evolving safety protocols are also common aspects of the role.
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Fractionation Technician jobs near you
Infographic showing various Fractionation Technician job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 84% Full Time, 11% Part Time, 3% Contract, and 1% Nights. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $54,605 per year, or $26.3 per hour.

Laboratory Technician - Biospecimen Operations

labconnect

Cleveland, OH

$18.50 - $24.50/hr

Full-time

Posted 10 days ago

Job description

Job Summary

The Laboratory Technician is responsible for sample processing and aliquoting. Process samples, including nucleic acid extractions, PBMC/BMMC isolations, plasma separation, specimen aliquoting, and other methods as required. Ensure sample integrity to meet client expectations.

Essential Duties and Responsibilities

  • Performs extraction and purification of nucleic acids as defined by relevant SOPs.

  • Performs methodologies as specified in technical protocols to isolate and stabilize blood cells (e.g. Peripheral Blood and Bone Marrow Mononuclear Cells) according to client specifications.

  • Performs aliquoting procedures on specified samples to produce sample aliquots that are volumetric or normalized as defined by client.

  • Performs blood/body fluid fractionation into components as requested by client.

  • Help document all required maintenance activities on instruments related to Sample Processing.

  • Help maintain adequate supply of reagents, supplies and sample processing kits.

  • Performs Quality analytics on extracted nucleic acids using applied methodologies and platforms (e.g. UV spectrophotometry) to determine sample yield, concentration, and purity.

  • Utilizes appropriate procedures to register and place prepared samples into specimen management database and storage location.

  • Communicate in a timely manner with cross-functional teams and operations staff to ensure client expectations are met.

  • Performs other related duties and tasks as necessary or as assigned.

Education and Experience

At least one of the following:

  • Bachelor’s degree, preferably in life science

  • Associate’s degree in a science or health-related field

  • Certificate in a science or health-related field and 6 months of laboratory experience

  • More than 1 year laboratory experience including sample processing and blood handling required.

  • MLS(ASCP) or MLT(ASCP) preferred

Skills and Ability

  • Working knowledge of requirements for sample processing in a clinical laboratory

  • Knowledgeable with universal precautions and human specimens

  • Strong attention to details, strong planning and problem-solving skills.

  • Strong organizational and time management skills, communication, multitasking, and interpersonal skills. 

  • Excellent listening and verbal comprehension skills, including ability to translate client’s needs to team members.

  • Self-motivation and ability to work independently as well as using a collaborative team approach.

  • Ability to adhere to established timelines, processes, and procedures.

  • Proficient in Microsoft Word, Excel, and database software.

  • Customer service/client relationship management skills. 

Supervisory Responsibilities:  None

Physical Demands: 

While performing the duties of this job, the occupant is regularly required to:

  • Sit 75% of the week.

  • Stand 25% of the week.

  • Walk and/or reach with hands and arms 75% of the week.

  • Read text of various sizes.

  • Communicate with others and hear.

  • Lift, pull and/or push up to 50 pounds.

  • Specific vision abilities include close vision and ability to adjust focus.

  • Exposure to dry ice and cold storage environments and biological samples.

Travel Requirements:  Minimal

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