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Fplc Jobs (NOW HIRING)

Perform chromatography of customer samples via FPLC and 2D-PAGE. * Analyze 2D-PAGE data with spot counting software and write reports. * Author SOPs and develop new data analysis tools. * Maintain ...

New

FPLC, ion exchange column, SEC column chromatography, ultrafiltration Comments/Special Instructions Additional Information All your information will be kept confidential according to EEO guidelines.

Protein expression, purification, and QC - 20% Express and purify polymerases, binders, and optogenetic protein components (primarily from bacteria) using affinity chromatography/FPLC and standard QC ...

Perform chromatography of customer samples via FPLC and 2D-PAGE. * Analyze 2D-PAGE data with spot counting software and write reports. * Author SOPs and develop new data analysis tools. * Maintain ...

New

Purification of proteins using baculoviruses and state of the art HPLC/FPLC equipment. Will manage genetically modified mouse colonies as well as assist in the management/coordination of a small ...

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Fplc information

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$36K

$69.1K

$97.5K

How much do fplc jobs pay per year?

As of Jul 14, 2026, the average yearly pay for fplc in the United States is $69,125.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,000.00 and $78,000.00 per year, depending on experience, location, and employer.

What are some typical challenges faced by FPLC operators and how can they be addressed?

FPLC (Fast Protein Liquid Chromatography) operators frequently encounter challenges such as maintaining consistent sample purity, troubleshooting equipment issues, and optimizing separation protocols for different proteins. To address these, it's important to develop strong problem-solving skills, stay up-to-date with equipment maintenance, and collaborate closely with research scientists to tailor protocols. Regular calibration of instruments and thorough documentation can greatly reduce errors and improve efficiency in the lab.

What are the key skills and qualifications needed to thrive as an FPLC (Fast Protein Liquid Chromatography) Specialist, and why are they important?

To thrive as an FPLC Specialist, you need a solid background in biochemistry, protein purification techniques, and a relevant science degree. Familiarity with chromatography systems such as ÄKTA, and experience with software like Unicorn for method development and data analysis, are typically required. Attention to detail, problem-solving skills, and effective communication are crucial soft skills in this role. These competencies ensure accurate purification processes, reliable results, and efficient collaboration in research or biomanufacturing environments.

What is an FPLC and what does an FPLC operator do?

FPLC stands for Fast Protein Liquid Chromatography, a technique used to separate and purify proteins from complex mixtures. An FPLC operator is responsible for setting up, running, and maintaining the FPLC system, preparing samples, monitoring purification runs, and analyzing collected fractions. They ensure the equipment operates correctly, troubleshoot issues, and maintain accurate records of purification protocols and results. FPLC operators often work in research labs, biotechnology companies, or pharmaceutical settings where purified proteins are needed for downstream applications.

What is the difference between Fplc vs Fpso?

AspectFplcFpso
Primary FunctionFabricates and installs pipelines and subsea equipment for offshore oil and gasProcesses and stores oil and gas on offshore platforms, then transfers to tankers
Work EnvironmentOffshore and onshore construction sitesOffshore platforms and processing facilities
Required CertificationsOffshore safety and welding certificationsOffshore safety, welding, and process operation certifications

Fplc (Floating Production, Liquefied Natural Gas, and Subsea Construction) specialists focus on installing subsea infrastructure, while Fpso (Floating Production Storage and Offloading) workers operate and maintain offshore production platforms. Both roles require offshore safety certifications and involve working in offshore environments, but their core responsibilities differ significantly in function and scope.

More about Fplc jobs
What states have the most Fplc jobs? States with the most job openings for Fplc jobs include:
Infographic showing various Fplc job openings in the United States as of July 2026, with employment types broken down into 86% Full Time, 7% Part Time, and 7% Contract. Highlights an 100% In-person job distribution, with an average salary of $69,125 per year, or $33.2 per hour.

Scientist / Senior Scientist, Protein Chemistry

The Fynder Group

Chicago, IL • On-site

$94K - $128K/yr

Full-time

Re-posted 15 days ago


Job description

We are seeking an innovative and driven Protein Chemist/Biochemist (Scientist / Senior Scientist) to join our dynamic R&D team. In this role, you will play a critical part in characterization of wild-type and genetically engineered fungal strains.  You will work at the intersection of protein biochemistry, proteomics, and molecular biology, with a focus on optimizing protein production and implementing different protein characterization methods, utilizing data-driven insights to solve complex technical challenges and accelerate relevant projects within the Fynder group. The ideal candidate thrives in a fast-paced, collaborative startup environment and possesses deep expertise in protein purification, advanced biophysical and bioanalytical characterization, and functional assay development.
Responsibilities
  • Protein Purification & Isolation: design, develop and optimize protein purification of native and heterologously expressed proteins from complex biological matrices. Execute purification workflows utilizing automated chromatography systems (e.g., affinity, ion exchange, size exclusion, hydrophobic interaction, ÄKTA FPLC chromatography platforms).

  • Advanced Characterization & Proteomics: Characterize the secretome and proteome of wild-type, engineered, and improved strains using biochemical, biophysical and analytical techniques, such as SDS-PAGE, western blotting, ELISA based assays, UV/vis spectroscopy, mass spectrometry, Bio-Layer Interferometry, flow cytometry, etc., to evaluate purity, structural integrity, post-translational modifications such as glycosylation, inter- and intra-molecular bonding, potency, stability, developability and functional activity.

  • Method & Assay Development: Independently design, develop, and optimize novel analytical methods and functional assays to determine structural and biophysical and biochemical attributes (e.g., molecular weight, aggregation, and stability).

  • High-Throughput Screening: Establish and execute high-throughput (HTP) micro-scale purification and screening workflows to rapidly evaluate large fungal variant libraries.

  • Cross-Functional Collaboration: Work within interdisciplinary teams and partner closely with molecular biology, strain engineering and fermentation teams to improve protein expression, yield, and product quality. 

  • Genotype-to-Phenotype Discovery: Partner closely with the molecular biology team to uncover connections between genotypes and key phenotypes of filamentous fungi, actively contributing to strain engineering and improvement strategies.

  • Execution & Data Analysis: Conduct hands-on, bench-top laboratory work, designing and troubleshooting independently, analyzing and interpreting data sets, and utilizing specialized software (e.g., Proteome Discoverer, UNIFI, PyMOL, or Prism) to deliver data-driven solutions to technical roadblocks.

  • Reporting & Presentation: Analyze and summarize results, maintaining meticulous experimental documentation, preparing SOPs, technical reports and presentations, and present scientific outcomes clearly and concisely to stakeholders.

  • Planning and Integration: Contribute to project planning, timelines and cross-functional scientific discussions.

Position Requirements & Qualifications
  • MS or Ph.D in Protein Chemistry, Biochemistry, or related field 
  • 2+ years of industrial experience
Technical Competencies: 
  • Deep knowledge of protein structure-function properties, advanced protein purification principles, structural characterization and understanding of protein chemistry, protein folding, aggregation and stability.

  • Experience with biologics characterization assays, including binding, blocking, competitive binding, functional activity using biochemical and cellular systems, etc

  • Proven hands-on expertise characterizing post-translational modifications, such as protein glycosylation profiles.

  • Experience with analytical instrumentation, including automated chromatography systems (FPLC/ÄKTA) and mass spectrometry (LC-MS/MS or MALDI-TOF), and analytical method development.

  • Experience working with microbial hosts and strain improvement programs focused on protein expression, metabolic engineering, or related applied research targets.

  • Familiarity with foundational computational software tools for structural visualization, data analytics, or proteomics pipelines (e.g., PyMOL, JMP, Prism, or equivalent).

Core Soft Skills & Attributes: 
  • Communication: Exceptional written, verbal, and interpersonal communication abilities required for cross-team coordination.

  • Teamwork & Mindset: An innovative mindset, a can-do attitude, and an intrinsic enthusiasm for engineering novel biological platforms for protein production.

  • Adaptability: Highly organized, detail-oriented, and perfectly comfortable navigating the fast-paced, shifting landscape of an early-to-mid stage biotech startup.

Preferred Qualifications:
  • Direct experience in quantifying and thoroughly structurally characterizing heterologously produced complex proteins.

  • Specific, hands-on scientific background working directly with filamentous fungi expression platforms.

  • Experience developing micro-scale high-throughput protein screening workflows or leveraging automated liquid handling systems.

  • Familiarity or basic working knowledge of industrial downstream processing (DSP) operations or engineering scale-up principles.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.