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Fplc Jobs (NOW HIRING)

Senior Scientist, Antibody Conjugation

Brisbane, CA · On-site

$110K - $150K/yr

Purify conjugates via FPLC/AKTA, TFF, and column chromatography; troubleshoot yield, homogeneity, and stability issues as they arise. * Write clear SOPs and technical reports; train and support ...

Purify protein purification using various chromatography techniques and FPLC equipment. * Collaborate with colleagues to characterize protein-protein and protein-ligand interactions using biophysical ...

Perform chromatography of customer samples via FPLC and 2D-PAGE. * Analyze 2D-PAGE data with spot counting software and write reports. * Author SOPs and develop new data analysis tools. * Maintain ...

FPLC, ion exchange column, SEC column chromatography, ultrafiltration Comments/Special Instructions Additional Information All your information will be kept confidential according to EEO guidelines.

Utilize HPLC, FPLC, and gravimetric separation techniques. * Analyze, interpret, and accurately document scientific data. * Support product quality and process consistency through careful laboratory ...

New

Perform chromatography of customer samples via FPLC and 2D-PAGE. * Analyze 2D-PAGE data with spot counting software and write reports. * Author SOPs and develop new data analysis tools. * Maintain ...

Purification of proteins using baculoviruses and state of the art HPLC/FPLC equipment. Will manage genetically modified mouse colonies as well as assist in the management/coordination of a small ...

Showing results 21-40

Fplc information

See salary details

$36K

$69.1K

$97.5K

How much do fplc jobs pay per year?

As of Aug 7, 2026, the average yearly pay for fplc in the United States is $69,125.00, according to ZipRecruiter salary data. Most workers in this role earn between $57,000.00 and $78,000.00 per year, depending on experience, location, and employer.

What are some typical challenges faced by FPLC operators and how can they be addressed?

FPLC (Fast Protein Liquid Chromatography) operators frequently encounter challenges such as maintaining consistent sample purity, troubleshooting equipment issues, and optimizing separation protocols for different proteins. To address these, it's important to develop strong problem-solving skills, stay up-to-date with equipment maintenance, and collaborate closely with research scientists to tailor protocols. Regular calibration of instruments and thorough documentation can greatly reduce errors and improve efficiency in the lab.

What are the key skills and qualifications needed to thrive as an FPLC specialist?

To thrive as an FPLC Specialist, you need a solid background in biochemistry, protein purification techniques, and a relevant science degree. Familiarity with chromatography systems such as ÄKTA, and experience with software like Unicorn for method development and data analysis, are typically required. Attention to detail, problem-solving skills, and effective communication are crucial soft skills in this role. These competencies ensure accurate purification processes, reliable results, and efficient collaboration in research or biomanufacturing environments.

What is an FPLC?

FPLC stands for Fast Protein Liquid Chromatography, a technique used to separate and purify proteins from complex mixtures. An FPLC operator is responsible for setting up, running, and maintaining the FPLC system, preparing samples, monitoring purification runs, and analyzing collected fractions. They ensure the equipment operates correctly, troubleshoot issues, and maintain accurate records of purification protocols and results. FPLC operators often work in research labs, biotechnology companies, or pharmaceutical settings where purified proteins are needed for downstream applications.

What is the difference between Fplc vs Fpso?

AspectFplcFpso
Primary FunctionFabricates and installs pipelines and subsea equipment for offshore oil and gasProcesses and stores oil and gas on offshore platforms, then transfers to tankers
Work EnvironmentOffshore and onshore construction sitesOffshore platforms and processing facilities
Required CertificationsOffshore safety and welding certificationsOffshore safety, welding, and process operation certifications

Fplc (Floating Production, Liquefied Natural Gas, and Subsea Construction) specialists focus on installing subsea infrastructure, while Fpso (Floating Production Storage and Offloading) workers operate and maintain offshore production platforms. Both roles require offshore safety certifications and involve working in offshore environments, but their core responsibilities differ significantly in function and scope.

More about Fplc jobs
What states have the most Fplc jobs? States with the most job openings for Fplc jobs include:
Infographic showing various Fplc job openings in the United States as of August 2026, with employment types broken down into 86% Full Time, 7% Part Time, and 7% Contract. Highlights an 100% In-person job distribution, with an average salary of $69,125 per year, or $33.2 per hour.

Senior Scientist, Antibody Conjugation

Nurix

Brisbane, CA • On-site

$110K - $150K/yr

Full-time

Posted 21 days ago


Job description

About the Role
We are growing the team with a hands-on antibody conjugation scientist who will build this capability from the ground up by developing and validating bioconjugation chemistries that are reproducible at bench scale, sufficiently robust for transfer to automated higher-throughput synthesis workflows, and scalable for preparation campaigns supporting advanced in vivo and translational studies.
This is a lab-based role for someone who wants to build a new technical capability inside an established, highly collaborative discovery organization and partner closely with medicinal chemistry, analytical chemistry, computational chemistry, protein biochemistry, and automation to move candidates from bench to study-ready material.
What You'll Do
  • Develop and optimize antibody bioconjugation methods for attaching degrader payloads and linkers to antibodies.
  • Design conjugation chemistry with an eye toward automation: define protocols, reagent ratios, and process parameters in a form that can be transferred to and run reliably on liquid-handling platforms.
  • Execute one-off and scale-up conjugation runs (mg to multi-mg) to produce material for pharmacology, PK/PD, and other advanced studies on program timelines.
  • Purify conjugates via FPLC/AKTA, TFF, and column chromatography; troubleshoot yield, homogeneity, and stability issues as they arise.
  • Write clear SOPs and technical reports; train and support automation-team colleagues in executing conjugation workflows independently.
  • Collaborate cross-functionally with medicinal chemists (linker/payload design), computational chemists (site selection, modeling), and external CROs/CDMOs as needed.
  • Stay current on emerging bioconjugation and DAC/ADC methodology and bring forward new techniques relevant to Nurix's pipeline.
Who You Are
  • A team player who works well across disciplines (chemistry, analytical, protein biochemistry, automation/engineering) and communicates clearly with both scientists and technical staff.
  • Results-oriented: you drive a method from first attempt to a robust, transferable protocol, and you personally deliver material when a study needs it.
  • Comfortable owning a technical area with real autonomy in a growing capability area.
Qualifications
  • PhD in chemistry, biochemistry, chemical biology, or a related field preferred; MS or BS with substantial (8+ for BS/MS) hands-on industry bioconjugation experience will also be considered.
  • Direct, hands-on experience with antibody/protein bioconjugation chemistry: NHS ester and maleimide coupling, click chemistry (CuAAC/SPAAC/IEDDA), engineered-cysteine or glycan/enzymatic site-specific conjugation, or unnatural-amino-acid approaches.
  • Experience purifying and characterizing conjugates: FPLC/AKTA, TFF, SEC, IEX, RP-HPLC/UPLC, HIC, and LC-MS-based DAR/identity analysis.
  • Experience preparing protocols for automated or semi-automated execution (e.g., liquid handlers such as Hamilton or Tecan) is a strong plus, though the successful candidate may also learn this in partnership with our automation team.
  • Strong record of practical problem-solving in the lab, with the judgment to know when a result is study-ready versus needs more optimization
Why This Role
You'll be the founding technical expert for antibody conjugation at Nurix, shaping both the science and how it's automated and scaled - with direct visibility to program leadership and a fast path from method development to real studies
Salary Range: 155K - 180K plus bonus and equity
Fit with Nurix Culture and Values
  • Strong team orientation; highly collaborative
  • Solutions and results-oriented focus
  • Hands-on approach; resourceful and open to diverse points of view

We are an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US.
Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job within Nurix or in the course of your employment with Nurix. By applying for a position with Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/)