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Formulation Lipid Nanoparticle Jobs (NOW HIRING)

CRISPR Therapeutics

Scientist II, LNP

Boston, MA · On-site

$130 - $140/hr

The ideal candidate will have experience in lipid nanoparticle (LNP) design, formulation and characterization, with proven experience in designing novel solutions for encapsulation of different ...

Crispr Therapeutics

Scientist II, LNP

Boston, MA

$130K - $140K/yr

The ideal candidate will have experience in lipid nanoparticle (LNP) design, formulation and characterization, with proven experience in designing novel solutions for encapsulation of different ...

Crispr Therapeutics

Scientist II, LNP

South Boston, MA · On-site

$130K - $140K/yr

The ideal candidate will have experience in lipid nanoparticle (LNP) design, formulation and characterization, with proven experience in designing novel solutions for encapsulation of different ...

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Formulation Lipid Nanoparticle information

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$55.5K

$119.5K

$174K

How much do formulation lipid nanoparticle jobs pay per year?

As of Aug 26, 2026, the average yearly pay for formulation lipid nanoparticle in the United States is $119,503.00, according to ZipRecruiter salary data. Most workers in this role earn between $101,500.00 and $150,000.00 per year, depending on experience, location, and employer.

What is a formulation lipid nanoparticle specialist?

Formulation Lipid Nanoparticle specialists are scientists or engineers who design and develop lipid nanoparticles (LNPs) for the delivery of drugs, vaccines, or genetic material. They work on optimizing the composition, stability, and effectiveness of LNPs to ensure safe and efficient delivery of therapeutic agents into target cells. Their expertise is crucial in pharmaceutical research and manufacturing, especially for advanced therapies like mRNA vaccines and gene therapies.

What are some common challenges faced when developing lipid nanoparticle (LNP) formulations, and how can these be addressed in a lab environment?

A key challenge in developing lipid nanoparticle formulations is achieving consistent particle size and encapsulation efficiency, which are critical for drug delivery applications. Variability can arise due to differences in lipid ratios, mixing techniques, and process parameters. To address this, team members often work closely with analytical chemists to optimize protocols, standardize procedures, and troubleshoot issues such as aggregation or low yield. Regular collaboration and clear documentation help ensure reproducibility and successful scale-up from bench to production.

What are the key skills and qualifications needed to thrive as a formulation lipid nanoparticle scientist, and why are they important?

To excel as a Formulation Lipid Nanoparticle Scientist, you need a solid background in chemistry, pharmaceutical sciences, or related fields, often supported by an advanced degree and experience in nanoparticle formulation. Familiarity with analytical instruments (HPLC, DLS, LC-MS), nanoparticle synthesis equipment, and regulatory standards is crucial, along with knowledge of relevant laboratory software. Strong problem-solving, attention to detail, and effective communication skills help in managing complex experiments and collaborating across multidisciplinary teams. These competencies ensure the successful design, optimization, and scale-up of lipid nanoparticle formulations for drug delivery and therapeutic applications.

What is the difference between Formulation Lipid Nanoparticle vs Formulation Scientist?

AspectFormulation Lipid NanoparticleFormulation Scientist
Required CredentialsBachelor's or Master's in Pharmaceutical Sciences, Chemistry, or related fieldsBachelor's or Master's in Pharmaceutical Sciences, Chemistry, or related fields
Work EnvironmentLaboratories focused on nanoparticle formulation and drug deliveryResearch and development labs, manufacturing, or quality control
Industry UsageSpecialized in lipid-based drug delivery systemsBroader role in formulation development across various drug types

Formulation Lipid Nanoparticle specialists focus specifically on developing lipid-based nanocarriers for drug delivery, requiring expertise in nanoparticle technology. Formulation Scientists have a broader scope, working on various formulation types, including lipid nanoparticles, but with less specialization. Both roles often require similar educational backgrounds and work in related environments, but their focus areas differ significantly.

How do you formulate lipid nanoparticles?

Formulation of lipid nanoparticles involves dissolving lipids and surfactants in an organic solvent, then combining this with an aqueous phase under controlled conditions such as sonication or high-pressure homogenization to produce uniform nanoparticles. Precise control of temperature, lipid composition, and process parameters is essential for achieving desired particle size and stability, often requiring specialized equipment and formulation expertise.
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Formulation Lipid Nanoparticle jobs near you
Infographic showing various Formulation Lipid Nanoparticle job openings in the United States as of August 2026, with employment types broken down into 2% As Needed, 81% Full Time, 11% Part Time, 3% Contract, and 3% Nights. Highlights an 89% Physical, 2% Hybrid, and 9% Remote job distribution, with an average salary of $119,503 per year, or $57.5 per hour.

Lipid Nanoparticle Formulation Senior Scientist to Associate Director

San Diego, CA • On-site

New Co.,
See more jobs at New Co.,external

Other

Medical, Dental, Vision, Life, Retirement

Re-posted 16 days ago

Job description

Company Description

We are a privately held, stealth mode start-up biotechnology company developing lipid nanoparticle-based approaches to address unmet medical needs.


The Role

We are seeking an experienced hands-on and strategic Lipid Nanoparticle (LNP) Formulation Scientist to drive the design, execution, and analysis of Design of Experiments (DOE) to establish cutting-edge next-generation LNP platforms focusing on different disease areas. This role will play a critical part in developing, optimizing, and characterizing LNP systems for nucleic acid delivery in a fast-paced, collaborative research environment.


Key responsibilities

• Design, execute, and analyze DOE-based formulation experiments to develop and optimize novel LNP formulations

• Lead formulation innovation efforts, including lipid selection, composition optimization, and novel process development

• Perform LNP screening and characterization, including size, PDI, encapsulation efficiency, stability, and performance metrics

• Lead formulation process scale-up and technology transfer as needed

• Collaborate closely with cross-functional teams (biology, analytics, chemistry, and project management) to advance programs

• Maintain thorough experimental documentation and clearly communicate results and recommendations to stakeholders

• Contribute to troubleshooting formulation challenges and continuously improve experimental workflows


Professional experience and qualifications

•Senior Scientist, PhD in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, Biology, or related field with 3-5 years relevant experience;

•Principal Scientist or Associate Director, PhD in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, Biology, or related field with 6+ years relevant experience

• Strong hands-on experience with LNP formulations, including formulation development and optimization, process development and scaling-up

• Demonstrated expertise in DOE methodologies and statistical experimental design

• Extensive experience with LNP screening and analytical techniques

• Deep understanding of lipid-based delivery systems and formulation science principles

• Proven ability to work effectively in a team-oriented, fast-paced environment

• Strong problem-solving skills and ability to manage multiple priorities simultaneously

• Strong communication skills for presenting data and influencing technical decisions


What We Offer

• Opportunity to work at the forefront of LNP formulation innovation

• Collaborative, science-driven culture with high impact research

• Competitive compensation and benefits package, including health, dental, vision, and life insurance

• 401(k) with company match


Apply