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Formulation Lipid Nanoparticle Jobs (NOW HIRING)

The ideal candidate will have experience in lipid nanoparticle (LNP) design, formulation and characterization, with proven experience in designing novel solutions for encapsulation of different ...

Scientist II, LNP

South Boston, MA · On-site

$130K - $140K/yr

The ideal candidate will have experience in lipid nanoparticle (LNP) design, formulation and characterization, with proven experience in designing novel solutions for encapsulation of different ...

... lipid nanoparticle (LNP) gene editing platform. This role requires deep expertise in LC/MS and ... Support formulation development, process development, and stability studies by providing timely ...

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Formulation Lipid Nanoparticle information

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$55.5K

$119.5K

$174K

How much do formulation lipid nanoparticle jobs pay per year?

As of Aug 4, 2026, the average yearly pay for formulation lipid nanoparticle in the United States is $119,503.00, according to ZipRecruiter salary data. Most workers in this role earn between $101,500.00 and $150,000.00 per year, depending on experience, location, and employer.

What is a formulation lipid nanoparticle specialist?

Formulation Lipid Nanoparticle specialists are scientists or engineers who design and develop lipid nanoparticles (LNPs) for the delivery of drugs, vaccines, or genetic material. They work on optimizing the composition, stability, and effectiveness of LNPs to ensure safe and efficient delivery of therapeutic agents into target cells. Their expertise is crucial in pharmaceutical research and manufacturing, especially for advanced therapies like mRNA vaccines and gene therapies.

What are some common challenges faced when developing lipid nanoparticle (LNP) formulations, and how can these be addressed in a lab environment?

A key challenge in developing lipid nanoparticle formulations is achieving consistent particle size and encapsulation efficiency, which are critical for drug delivery applications. Variability can arise due to differences in lipid ratios, mixing techniques, and process parameters. To address this, team members often work closely with analytical chemists to optimize protocols, standardize procedures, and troubleshoot issues such as aggregation or low yield. Regular collaboration and clear documentation help ensure reproducibility and successful scale-up from bench to production.

What is the difference between Formulation Lipid Nanoparticle vs Formulation Scientist?

AspectFormulation Lipid NanoparticleFormulation Scientist
Required CredentialsBachelor's or Master's in Pharmaceutical Sciences, Chemistry, or related fieldsBachelor's or Master's in Pharmaceutical Sciences, Chemistry, or related fields
Work EnvironmentLaboratories focused on nanoparticle formulation and drug deliveryResearch and development labs, manufacturing, or quality control
Industry UsageSpecialized in lipid-based drug delivery systemsBroader role in formulation development across various drug types

Formulation Lipid Nanoparticle specialists focus specifically on developing lipid-based nanocarriers for drug delivery, requiring expertise in nanoparticle technology. Formulation Scientists have a broader scope, working on various formulation types, including lipid nanoparticles, but with less specialization. Both roles often require similar educational backgrounds and work in related environments, but their focus areas differ significantly.

What are the key skills and qualifications needed to thrive as a formulation lipid nanoparticle scientist, and why are they important?

To excel as a Formulation Lipid Nanoparticle Scientist, you need a solid background in chemistry, pharmaceutical sciences, or related fields, often supported by an advanced degree and experience in nanoparticle formulation. Familiarity with analytical instruments (HPLC, DLS, LC-MS), nanoparticle synthesis equipment, and regulatory standards is crucial, along with knowledge of relevant laboratory software. Strong problem-solving, attention to detail, and effective communication skills help in managing complex experiments and collaborating across multidisciplinary teams. These competencies ensure the successful design, optimization, and scale-up of lipid nanoparticle formulations for drug delivery and therapeutic applications.
More about Formulation Lipid Nanoparticle jobs
What cities are hiring for Formulation Lipid Nanoparticle jobs? Cities with the most Formulation Lipid Nanoparticle job openings:
What states have the most Formulation Lipid Nanoparticle jobs? States with the most job openings for Formulation Lipid Nanoparticle jobs include:
Infographic showing various Formulation Lipid Nanoparticle job openings in the United States as of July 2026, with employment types broken down into 1% As Needed, 82% Full Time, 14% Part Time, 1% Temporary, and 2% Contract. Highlights an 89% Physical, 2% Hybrid, and 9% Remote job distribution, with an average salary of $119,503 per year, or $57.5 per hour.

Associate Scientist, Formulation, Pilot Lab

Sail Biomedicines

Cambridge, MA

$95K - $120K/yr

Other

Posted 8 days ago


Job description

Sail Biomedicines is seeking a scientist to advance our lipid nanoparticle (LNP) manufacturing platform for nucleic acid therapeutics. Sail Biomedicines is seeking a highly talented and self-motivated individual to develop and operationalize lipid nanoparticle formulations at pre-clinical and pilot lab scales. The successful candidate will contribute to preclinical pipeline programs, working at interface of manufacturing, formulation science, analytical characterization, and process development.

KEY RESPONSIBILITIES

  • Design, formulate, and characterize lipid nanoparticle (LNP) systems for nucleic acid delivery across preclinical manufacturing and technology development stages.
  • Develop, optimize and operationalize formulation processes and scale-up approaches (e.g., TFF, ultrafiltration)
  • Troubleshoot formulation and process challenges to enhance robustness, reproducibility, and scalability
  • Generate high-quality, reproducible data and maintain thorough documentation in electronic lab notebooks
  • Prepare LNP formulations to support internal research and partner programs
  • Collaborate cross-functionally with analytical, translational and platform teams to advance pre-clincial manufacturing and pilot lab goals
  • Present data and insights clearly to internal teams and contribute to scientific discussions and decision-making

PROFESSIONAL EXPERIENCE & QUALIFICATIONS

  • 4+ years (M.Sc.) or 6+ years (B.Sc.) of relevant industry experience in LNP formulation optimizations and drug delivery with strong background in nucleic acid therapeutics and education in life sciences or engineering (Pharmaceutical Sciences, Biomedical Engineering, Biochemistry, etc)
    • Level (Associate Scientist or Scientist I) will be determined based on experience, technical expertise, and demonstrated impact.
  • Hands-on experience in nanoparticle or LNP formulation and characterization
  • Strong understanding of drug delivery systems, particularly for nucleic acid therapeutics
  • Experience with nanoparticle characterization techniques (e.g., DLS, zeta potential, fluorescence-based assays such as Ribogreen, chromatography)
  • Demonstrated ability to design, execute, and troubleshoot experiments independently
  • Strong data analysis, documentation, and communication skills

PREFERRED QUALIFICATIONS

  • Familiarity with formulation process technologies (e.g., microfluidic mixers, pumping systems, TFF)
  • Experience supporting in vivo studies or translating formulations from research to preclinical scale

Salary Range: $95,000 - $120,000

Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate based on race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.