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School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Duke Cancer Institute's Phase 1 and Immunotherapy Program (PHIIT) is seeking a highly skilled Clinical Research Nurse Coordinator to join our dynamic Oncology Clinical Research Unit (CRU). In this critical role, you will lead and coordinate complex oncology clinical trials, including first-in-human studies and investigational therapies that are advancing the future of cancer care.

You will work at the forefront of innovation-partnering closely with physicians, researchers, and multidisciplinary teams to bring cutting-edge treatments to patients. From study start-up through closeout, you will be a central driver of clinical trial execution, ensuring excellence in patient care, regulatory compliance, and data integrity.

In your day-to-day work, you will engage directly with patients-guiding them through the clinical trial process, administering specialized treatments such as chemotherapy, monitoring for adverse events, and providing education on investigational therapies. You will also collaborate with sponsors, manage study operations, and contribute to the development of new research initiatives.

This is an exceptional opportunity for a nurse who is passionate about oncology, research, and patient-centered care to make a meaningful impact in advancing life-saving therapies.

Minimum Requirements:

• Graduation from an accredited BSN program, Associate Degree in Nursing, or Nursing Diploma program
• Current or compact RN licensure in the state of North Carolina
• BLS certification required
• Minimum 12 months of clinical nursing experience
• If not BSN-prepared, must enroll in a BSN program within two years and complete within seven years
• Maintain compliance with all hospital and unit-specific competencies and training requirements

Preferred Qualifications:

• Experience in oncology, clinical research, or intensive care (ICU)
• Experience with clinical trials, investigational products, or protocol-driven care
• Familiarity with Electronic Data Capture (EDC) systems and research documentation
• Strong ability to manage complex workflows and collaborate with multidisciplinary teams

Other Requirements:

• Ability to administer adult chemotherapy and ambulatory medications
• Clinical competencies including dysrhythmia review, lab interpretation, and adverse event assessment
• Participation in continuing education and maintenance of required certifications

Be Bold.

Position Description:

• Coordinate and manage oncology clinical trials by recruiting, screening, consenting, and enrolling participants while ensuring adherence to study protocols and regulatory requirements
• Deliver direct patient care in a research setting, including medication administration, chemotherapy delivery, patient education, and monitoring for adverse events and treatment compliance
• Oversee study operations and compliance, maintaining regulatory documentation, reporting adverse events, supporting audits, and ensuring alignment with institutional policies, SOPs, and federal guidelines
• Collaborate with investigators, sponsors, and cross-functional teams to execute study activities, resolve issues, support monitoring visits, and contribute to study start-up and closeout processes
• Support financial and data management efforts, including budget development, tracking study milestones, entering and validating clinical data, and ensuring data accuracy, security, and completeness

Choose Duke.

Join Duke Cancer Institute-one of the nation's leading cancer centers-where innovation, discovery, and compassionate care come together to transform patient outcomes. As part of the Oncology Clinical Research Unit, you will contribute to groundbreaking Phase 1 and immunotherapy trials that are shaping the future of cancer treatment worldwide.

At Duke, you will find a collaborative and inclusive environment that values professional growth, continuous learning, and clinical excellence. You will have opportunities to participate in research publications, mentor colleagues, and advance your career within a nationally recognized academic health system.