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Downstream Protein Purification Phd Jobs in Riverside, CA

Fortive

Staff Scientist

Irvine, CA · On-site

Collaborate on the studies for enzyme purification and activity control with biochemistry SME ... Fermentation on microbial liquid culture and its upstream and downstream process experience are ...

All JobsDownstream Protein Purification Phd JobsDownstream Protein Purification Phd Jobs in Riverside, CA

Downstream Protein Purification Phd information

See Riverside, CA salary details

$14

$26

$36

How much do downstream protein purification phd jobs pay per hour?

As of Aug 25, 2026, the average hourly pay for downstream protein purification phd in Riverside, CA is $26.03, according to ZipRecruiter salary data. Most workers in this role earn between $21.06 and $30.10 per hour, depending on experience, location, and employer.

What is a downstream protein purification PhD?

A Downstream Protein Purification PhD refers to an individual who has earned a doctoral degree specializing in the purification of proteins after they have been expressed in a host organism, typically as part of biopharmaceutical production. Downstream protein purification focuses on isolating, purifying, and characterizing target proteins from complex mixtures using various biochemical and biophysical methods. Professionals in this field are experts in techniques like chromatography, filtration, and centrifugation, ensuring the final product meets purity and quality standards required for research or therapeutic use.

What are the key skills and qualifications needed to thrive as a downstream protein purification PhD?

To thrive as a Downstream Protein Purification PhD, you need an advanced understanding of protein chemistry, chromatography, and bioprocess engineering, typically supported by a PhD in biochemistry, biotechnology, or a related field. Familiarity with purification systems (such as AKTA), analytical tools (like HPLC), and regulatory standards (cGMP) is crucial. Strong problem-solving, attention to detail, and effective communication help drive process optimization and successful collaboration with multidisciplinary teams. These skills ensure robust, scalable purification processes that meet quality and regulatory requirements in biopharmaceutical production.

What are some common challenges faced in a downstream protein purification PhD role and how can they be addressed?

One common challenge in a Downstream Protein Purification PhD role is optimizing purification protocols for novel or complex proteins, which often requires troubleshooting issues like low yield, aggregation, or impurities. Addressing these challenges typically involves iterative experimentation, staying updated on emerging purification technologies, and collaborating closely with upstream teams and analytical scientists. Additionally, balancing project timelines with the need for thorough documentation and compliance with regulatory standards is essential. Being proactive in cross-functional communication and leveraging automation or high-throughput techniques can also help streamline workflows and improve outcomes.

What is the difference between Downstream Protein Purification Phd vs Downstream Processing Scientist?

AspectDownstream Protein Purification PhdDownstream Processing Scientist
Required CredentialsPhD in Biochemistry, Molecular Biology, or related fieldBachelor's or Master's in Life Sciences or Chemical Engineering
Work EnvironmentResearch labs, biotech, pharmaceutical companiesManufacturing facilities, biotech, pharma industries
Employer & Industry UsageAcademic research, biotech R&D, pharmaceutical developmentProduction, process development, quality control

While both roles involve working with bioprocesses, a Downstream Protein Purification Phd typically focuses on advanced research and development of purification techniques, often in academic or R&D settings. In contrast, a Downstream Processing Scientist usually works in manufacturing environments, applying established protocols to produce and purify biotherapeutics at scale. The Phd role emphasizes innovation and experimental design, whereas the scientist role centers on process optimization and production efficiency.

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Cities near Riverside, CA with the most Downstream Protein Purification Phd job openings:

Downstream Protein Purification Phd jobs near you

Scientist, Downstream Process Development

Avid Bioservices

Tustin, CA • On-site

$124K - $155K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 3 days ago

Job description

Description
Looking to join a passionate team dedicated to developing and manufacturing life-saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes.
Your Role:
The Scientist, Downstream Process Development, will support the development and optimization of downstream purification processes for protein-based biologics. Responsibilities include chromatography and filtration process development, scale-up and technology transfer activities, viral clearance studies, and data analysis. The individual will collaborate closely with Upstream Process Development, Analytical Sciences, MSAT, Manufacturing, Program Management, and clients to advance development programs from early-stage development through manufacturing.
Key Responsibilities:
  • Demonstrated expertise in downstream process development for monoclonal antibodies, recombinant proteins, and other biologic modalities, including chromatography, filtration, buffer development, and process scale-up.
  • Strong understanding of protein purification principles, process characterization, experimental design, statistical data analysis, and biopharmaceutical development workflows.
  • Experience leading technical projects, troubleshooting complex process challenges, and driving development strategies with minimal supervision.
  • Demonstrated ability to analyze, interpret, and present scientific data, author technical reports, and communicate findings effectively to internal and external stakeholders.
  • Experience supporting technology transfer, manufacturing process implementation, and cross-functional collaboration within a GMP-regulated environment is highly desirable.
  • Knowledge of process analytical technologies (PAT), laboratory automation, high-throughput process development, process intensification, and digital data management tools is preferred.
  • Proven ability to mentor junior scientists and provide scientific leadership across project teams.
  • Excellent written and verbal communication skills, with experience interacting directly with clients, partners, and senior leadership.
  • Working knowledge of regulatory expectations and CMC development activities supporting clinical and commercial biologics programs is desirable.
  • Occasional travel by land and/or air may be required to attend seminars or conferences or client meetings.

Minimum Qualifications:
  • Ph.D. in Chemical Engineering, Biochemical Engineering, Biotechnology, Biological Sciences, or a related discipline with 0-3 years of relevant industry experience; OR M.S. degree with 5+ years; OR B.S. degree with 8+ years of relevant biopharmaceutical industry experience.

Preferred Qualifications:
  • Ph.D. in Biochemistry, Chemistry, or related field with 1-2 years or M.S. with 3-5 years of industry experience.
  • Prior experience in leading downstream process development of biologics is a plus.
  • Experience mentoring or leading scientific staff preferred.

Position Type/Expected Hours of Work:
This role is a full-time onsite position. Days and hours of work are Monday through Friday unless otherwise stated by Supervisor. The employee must also have the ability to work overtime and/or weekends when necessary.
Compensation:
We offer competitive compensation packages for this role, including a base salary, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.
The compensation range for this role is $124,000 - $155,000 annually depending on experience and qualifications. Additionally, we offer opportunities for career growth and development as well as a supportive and inclusive work environment.
Who you are:
  • You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
  • Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
  • You have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.
  • You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.

Physical Demands & Work Environment:
In this dynamic role, expect a blend of regular activities like sitting, standing, and walking, with occasional physically engaging tasks such as lifting objects up to 25 pounds. The work environment might expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels occasionally. However, reasonable accommodations are available to enable individuals with different abilities to perform effectively, ensuring a supportive and adaptable work setting. Your visual acuity, including close, distance, and color vision, will be essential in navigating through the diverse day-to-day demands of this position.

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