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Downstream Process Jobs in Missouri (NOW HIRING)

CMMG, Inc.

Production / Warehouse Associate

Boonville, MO · On-site

$12.25 - $15.50/hr

Ensure items are properly assembled, labeled, and prepared for downstream processes. * Assemble small miscellaneous parts and package in labeled bags with barcodes. * Produce work in a safe and ...

CMMG

Production / Warehouse Associate

Boonville, MO · On-site

$12.25 - $15.50/hr

Ensure items are properly assembled, labeled, and prepared for downstream processes. * Assemble small miscellaneous parts and package in labeled bags with barcodes. * Produce work in a safe and ...

Washington University of St. Louis

$16.92 - $26.44/hr

Retrieves samples from the biobank and processes for downstream applications/analyses. * Complies with established safety procedures and maintains required documentation on laboratory and specimen ...

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Downstream Process information

What are some common challenges faced by professionals working in downstream process roles?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What are the key skills and qualifications needed to thrive as a downstream process engineer?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What is a downstream process?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.
What are popular job titles related to Downstream Process jobs in Missouri? For Downstream Process jobs in Missouri, the most frequently searched job titles are:
What job categories do people searching Downstream Process jobs in Missouri look for? The top searched job categories for Downstream Process jobs in Missouri are:
Downstream Process jobs near you
Infographic showing various Downstream Process job openings in Missouri as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 16% Part Time, 4% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution.

Senior System Administrator - Wealth Management

Commerce Bank

Saint Louis, MO • On-site

$93K - $109K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 13 days ago

Job description

About Working at Commerce
Building a career here is more than just steps on a ladder. It's about helping people find financial safety and success, helping businesses thrive, and making sure people and their money are taken care of. And our commitment doesn't stop there. Our culture is about our people, the ones in our communities and the ones that work with us.
Here, you'll find opportunities to grow and learn, to connect with others, and build relationships with the people around you. You'll have the space and resources to grow into the best version of yourself. Because our number one investment is you.
Creating an award-winning culture doesn't come easy. And after 160 years, we know Commerce Bank is only at its best when our people are. If this sounds interesting to you, keep reading and let's talk.
Compensation Range
Annual Salary: $93,000.00 - $109,000.00 (Amount based on relevant experience, skills, and competencies.)
For more than a century, Commerce Trust has been a leading provider of wealth management services including financial planning, estate and tax planning, investment management, private banking and trust administration services. Our approach to wealth management means assembling a team of seasoned wealth management professionals across disciplines who collaborate to ensure each client's financial journey is uniquely crafted for their goals. Commerce Trust is a division of Commerce Bank.
About This Job
The main purpose of this job is to build and maintain our sales and incentive reporting software tied directly to the growth of the wealth division. Core responsibilities include project management, new builds, implementing system enhancements and data management.
Essential Functions
  • Own, design, build and deliver projects outlined in the department's roadmap related to the incentive compensation management and performance management systems
  • Responsible for capturing business requirements, system configuration, workflow design, analyzing and testing results, aligning downstream processes and implementing solutions using department applications; Partner in cooperation with internal information systems departments & vendors.
  • Provide technical direction, maintenance, and support for department applications, and act as
    the business and system resource. Ensure proper use of test and production environments
  • Create and maintain documentation of processes, policies, application configuration, and
    other 'guide' materials for internal user base
  • Work with team members to identify and resolve incidents using defined processes
  • Partner with team and management in the planning & executing of process improvements
  • Participate in team-wide efforts to accomplish organizational & departmental initiatives
  • Perform other duties as assigned

Knowledge, Skills & Abilities Required
  • Strong understanding of operations, governance, and controls that can impact systems and calculations
  • Strong ability to perform data validation, develop processes and deliver efficient end user solutions
  • Ability to visualize and translate business needs into technological solutions
  • Strong ability to translate and summarize technical to business applications, often with an executive audience
  • Solid grasp of integrations, workflow solutions, database concepts, hierarchy/access controls, and reporting/analytics solutions
  • Ability to use platform applications to refine data, perform advanced logic-based calculations and leverage some SQL code
  • Ability to model business processes using a variety of tools and techniques
  • Capable of working both independently and within a group to deliver results
  • Ability to maintain a high degree of professionalism and confidentiality
  • Highly motivated and organized self-starter with strong attention to detail and the ability to manage multiple priorities
  • Inquisitive, agile and strong team player with excellent written, verbal and interpersonal
    communication skills
  • Ability to remain adaptable and resilient to all situations with an optimistic outlook and cast a
    positive shadow that is aligned with our culture and Core Values
  • Strong level of proficiency with Microsoft Office 365, including advanced Excel

Education & Experience
  • Bachelor's degree or equivalent combination of education and experience required
  • 5+ years experience with data analytics and project management required
  • Extensive experience working with Excel and database environments required
  • Experience working with complex data environments and enterprise applications (SAP, Workday, Performio, Databricks, Salesforce, etc.) preferred
  • Experience with compensation and/or performance metrics preferred
  • Experience in the financial industry (investments or banking) preferred

**Level of role is determined by knowledge, experience, skills, abilities, and education.
***For individuals applying, assigned and/or hired to work in areas with pay transparency requirements, Commerce is required by law to include a reasonable estimate of the compensation range for some roles. This compensation range is for the Senior Systems Administrator - CTC job and contemplates a wide range of factors that are considered in making compensation decisions, including but not limited to location, skill sets, education, relevant experience and training, licensure and certifications, and other business and organizational needs. The disclosed range estimate has not been adjusted for any applicable differentials (geographic, bilingual, or shift) that could be associated with the position or where it is filled. At Commerce, compensation decisions are dependent on the facts and circumstances of each situation. A reasonable estimate of the current base pay is $93,000 to $109,000 annually.
#LI-AC1
The candidate selected for this position may be eligible for the following employment benefits: employer sponsored health, dental, and vision insurance, 401(k), life insurance, paid vacation, and paid personal time. In addition, we offer career development, education assistance, and voluntary supplemental benefits. Click here to learn more.
Location: 8000 Forsyth Blvd, Clayton, Missouri 63105
Time Type:
Full time

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