Downstream Process Jobs in Massachusetts (NOW HIRING)

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Join Takeda as a Downstream Process Development, Engineer II. As an early-career professional, you handle problems of limited scope and complexity, adhering to established policies and procedures. Your decision-making is within a defined scope, using standardized methods to analyze situations and data. You are developing knowledge of basic principles, theories, and concepts, and beginning to apply industry practices and standards. Typically, this role requires some relevant experience, with contributions mostly related to task-specific activities. Your primary contacts are with your immediate team, and you work under moderate direction and close supervision, following specific, detailed instructions.

The Downstream Process Development, Engineer II is responsible for supporting downstream biotherapeutics process development through hands-on purification and recovery development experiments. This individual contributor role supports process development across multiple scales, from micro scale through bench and pilot scale, and contributes to both early-stage and late-stage programs. You will work in teams with more senior process engineers to collaboratively execute larger experiments, while also working closely with process development team members to generate data, maintain accurate records, and contribute to the development and optimization of downstream processes.

Execute chromatography, harvest operations, ultrafiltration and diafiltration (UF/DF), and viral clearance experiments with additional potential support of bioconjugation.
Support downstream process development across micro scale, bench scale, and pilot scale studies
Help maintain laboratory equipment and support routine readiness of instruments used in process development work
Work with more senior process engineers to collaboratively plan and execute larger experiments and study activities
Document experimental work in electronic laboratory notebooks and maintain clear, complete, and timely records
Perform basic data analysis to review trends, compare conditions, and support study conclusions
Prepare technical summaries, study updates, and other written materials to share results and findings
Follow established laboratory and process development procedures, including quality and safety requirements
Contribute to continuous improvement efforts by identifying ways to improve workflows, data capture, and experimental execution
Assist with small projects or specific project tasks under close supervision

Associate degree with 2+ years of relevant experience, or bachelor's degree with relevant experience, in chemical engineering, chemistry, biochemistry, biotechnology, or a related field
Experience with chromatography, harvest, ultrafiltration and diafiltration, and viral clearance steps
Comfort with emerging digital tools and openness to AI-enabled processes that support data analysis, documentation, and workflow improvement.
Experience with basic bioprocess control systems
Experience using electronic laboratory notebooks for study documentation/data entry
Ability to perform basic data analysis and present results clearly in written form
Familiarity with technical writing for laboratory reports or development documents
Understanding of laboratory practices, process development methods, and quality requirements
Ability to follow detailed procedures, maintain accurate records, and work under close supervision
Some relevant experience in process development, protein purification, or a related laboratory setting

At Takeda, our patients rely on us to deliver quality products. As a result, we must follow strict rules in our manufacturing facilities to ensure we are not endangering the quality of the product. In this role, you may:

• Work in a controlled environment requiring special gowning and wear protective clothing over the head, face, hands, feet and body. This may include additional hearing protection for loud areas.
• Need to remove all make-up, jewelry, contact lenses, nail polish and/or artificial fingernails while in the manufacturing environment.
• Work in a cold, wet environment.
• Work multiple shifts, including weekends, or be asked to work supplemental hours, as necessary.
• Work around chemicals such as alcohol, acids, buffers and Celite that may require respiratory protection.

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

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Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

U.S. Base Salary Range:

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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