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Downstream Process Development Jobs in Texas (NOW HIRING)

You will lead the development implementation and optimization of a robust manufacturing process of ... downstream. * Root Cause Analysis: Lead formal failure analysis and troubleshooting efforts.

You will lead the development implementation and optimization of a robust manufacturing process of ... downstream. * Root Cause Analysis: Lead formal failure analysis and troubleshooting efforts.

Senior Process Engineer

San Antonio, TX · On-site

$93K - $121K/yr

... configuration, cooling, and downstream equipment. * Partner with R&D to scale up new TPU ... Develop and maintain process documentation, including work instructions, control plans, and ...

Senior Process Engineer

San Antonio, TX · On-site

$93K - $121K/yr

... configuration, cooling, and downstream equipment. * Partner with R&D to scale up new TPU ... Develop and maintain process documentation, including work instructions, control plans, and ...

Senior Process Engineer

Katy, TX · On-site

$95K - $123K/yr

Through our people, we have developed a strong, contribution motivated, team with a reputation for ... Independently evaluate and design facilities for midstream and downstream projects * Basic ...

Senior Process Engineer

San Antonio, TX · On-site

$94K - $122K/yr

Sr. Process Engineer page is loaded## Sr. Process Engineerlocations: San Antonio, TXtime type: Full ... configuration, cooling, and downstream equipment.* Partner with R&D to scale up new TPU ...

... downstream processing conditions. 4. Works independently on standard projects while assistance is ... Demonstrated experience with extrusion process development, optimization and troubleshooting.

We are a boutique-sized diversified downstream energy company with a range of assets, including ... Participates in the evaluation of equipment design and process development to compromise between ...

We are a boutique-sized diversified downstream energy company with a range of assets, including ... Participates in the evaluation of equipment design and process development to compromise between ...

We are a boutique-sized diversified downstream energy company with a range of assets, including ... Participates in the evaluation of equipment design and process development to compromise between ...

... downstream processing conditions. 4. Works independently on standard projects while assistance is ... development in order to meet the needs of a medical device manufacturing organization. • ...

Lead Data Engineer 21699-1

Plano, TX · On-site

$98K - $130K/yr

Required : • Understand the business requirement or the downstream process requirement • ... Keylent provides Software Development Services in the Cloud, Analytics and Digital Transformation ...

Sr Process Engineer

Big Spring, TX · On-site

$96K - $124K/yr

We are a boutique-sized diversified downstream energy company with a range of assets, including ... Evaluates equipment design and process development to compromise between process requirements ...

Sr Process Engineer

Big Spring, TX · On-site

$96K - $124K/yr

We are a boutique-sized diversified downstream energy company with a range of assets, including ... Evaluates equipment design and process development to compromise between process requirements ...

Sino Biological's core technology platform is its in-house developed mammalian cell-based ... processes for the efficient production of antigens and antibodies. With its main manufacturing ...

Required : • Understand the business requirement or the downstream process requirement • ... Keylent provides Software Development Services in the Cloud, Analytics and Digital Transformation ...

Showing results 21-40

Downstream Process Development information

See Texas salary details

$17

$31

$46

How much do downstream process development jobs pay per hour?

As of Sep 10, 2026, the average hourly pay for downstream process development in Texas is $31.38, according to ZipRecruiter salary data. Most workers in this role earn between $25.77 and $38.51 per hour, depending on experience, location, and employer.

What is downstream process development?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What does someone in downstream process development do?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are the key skills and qualifications needed for downstream process development?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

What are popular job titles related to Downstream Process Development jobs in Texas?

For Downstream Process Development jobs in Texas, the most frequently searched job titles are:

What job categories do people searching Downstream Process Development jobs in Texas look for?

The top searched job categories for Downstream Process Development jobs in Texas are:

Infographic showing various Downstream Process Development job openings in Texas as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 81% Full Time, 15% Part Time, and 2% Contract. Highlights an 86% Physical, 2% Hybrid, and 12% Remote job distribution, with an average salary of $65,272 per year, or $31.4 per hour.

Process Engineer

Houston, TX • On-site

Full-time

Re-posted 12 days ago


Key responsibilities

  • Own the development, implementation, and optimization of the manufacturing process for complex humanoid robots.

  • Design and manage the factory layout, process flow, and assembly sequencing to ensure efficient production.

  • Partner with cross-functional teams to improve production metrics, troubleshoot issues, and ensure process quality.


Job description

Job Title: Senior Process Engineer
Department: Manufacturing
Reports To: Head of Global Manufacturing
Employment Type: Full-Time
Location: Houston, TX
Persona AI is developing and commercializing rugged, multi-purpose humanoid robots that perform real work. Persona's founding team has a decades-long history in humanoid robotics, bionics, and product development delivering robust hardware that has touched the stars, worked miles below the surface of the ocean, roamed Disney Parks, and has even been featured on a US postage stamp. Our mission is focused squarely on shipping beautiful, reliable products at massive scale, while building a customer-focused team to achieve these aims.
Role Overview:
We're looking for a Senior Process Engineer to join our manufacturing team and build Persona's production system from the ground up. This person will report into and function as the right hand to Persona's Head of Manufacturing. You will lead the development implementation and optimization of a robust manufacturing process of complex humanoid robots. You'll own the complete manufacturing process architecture: including process development, assembly sequencing, factory layout, and scalability.
Responsibilities:
  • Factory Layout & Process Flow: Own the physical and operational design of Persona's manufacturing environment. How the factory is laid out, how sub-assemblies and finished robots move through the space, and how each station connects to the next. Think flow, not in tasks.
  • Process Development: Define and document every step in the robot build sequence from incoming components to final test. Build the work instructions, station designs, and standard work that make every build repeatable regardless of who's on the floor.
  • Equipment Specification & Procurement: Identify, spec, and own the capital equipment and tooling needed to build robots right. You'll make the call on what to buy, justify it, and integrate it into the line.
  • Metrics & Visual Management: Design the factory floor metrics and display systems so that anyone, from a new technician to a first-time visitor, can walk the floor and immediately understand build status, throughput, and where problems are.
  • Poka-Yoke & Error-Proofing: Partner with the Quality Lead to design processes and fixtures where the right build is the only possible build. Mistake-proof the line at the process level so quality is built in, not inspected in.
  • Continuous Improvement: As Persona scales from tens of robots to hundreds, you will own the ongoing optimization of the production system like cycle time, yield, throughput, and cost per unit. Apply lean and kaizen principles to eliminate waste as the line matures.
  • Cross-Functional Collaboration: Work closely with the Quality Lead, Supply Chain Lead, and assembly technicians. Partner with engineering during design reviews to influence DFM/DFA decisions upstream before they become production problems downstream.
  • Root Cause Analysis: Lead formal failure analysis and troubleshooting efforts. Institute the use of problem solving tools such as 8D, CAPA and other.
  • Compliance & Safety: In addition to ISO9001, Persona will pursue compliance with newly established ISO & safety certifications for humanoid robots.

Qualifications:
  • 10-15+ years in manufacturing or process engineering in a complex hardware environment like robotics, automotive (OEM or Tier 1/2 supplier), aerospace, industrial equipment, or consumer electronics
  • Proven experience or strong aptitude to design and build production systems from the ground up
  • Experience with implementation of MES systems (Tulip, ProPlanner, or like)
  • Deep knowledge of factory layout, line design, and process flow. You've moved equipment around on paper (and in practice) and know how to design a build sequence that actually works
  • Hands-on experience with lean manufacturing principles: standard work, poka-yoke, 5S, kaizen, value stream mapping
  • Strong DFM/DFA instincts. You're comfortable pushing back on engineering when a design will create production problems
  • Experience specifying and integrating capital equipment and production tooling
  • Ability to read and interpret technical drawings, GD&T, and assembly documentation
  • Comfortable working directly with technicians on the floor - this role is as much floor leadership as it is engineering
  • Houston-based or willing to relocate

Why Join Persona AI?
Most process engineering jobs are optimization problems - someone else built the line, and you make it run better. This one is a creation problem. You'll design how Persona's robots get built: the layout, the flow, the stations, the metrics, the equipment. When Persona ships at scale, this is the system you built. That's not a common opportunity, and it's not a common thing to be able to say.
You'll have a front-row seat to the evolution of humanoid robotics, with the opportunity to shape our systems and scale our manufacturing from the ground up. If you're energized by early-stage innovation, hands-on engineering, and building things that push boundaries, we'd love to hear from you.
Persona AI is an Equal Opportunity Employer.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by applicable federal, state, or local law.