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Downstream Process Development Jobs in Texas (NOW HIRING)

Lonza

Scientist II, Downstream

Houston, TX · On-site

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

Lonza

Scientist II, Downstream

Houston, TX · On-site

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

MaverickX

Senior Bio Process Engineer

Austin, TX

$103.10K - $133.30K/yr

... Development, and Finance. You will sit at the intersection of process, production, and ... You will oversee reactor performance, downstream processing, and plant operations, ensuring that ...

MaverickX

Senior Bio Process Engineer

Austin, TX · On-site

$103.10K - $133.30K/yr

... Development, and Finance. You will sit at the intersection of process, production, and ... You will oversee reactor performance, downstream processing, and plant operations, ensuring that ...

XPEL, Inc.

Senior Process Engineer

San Antonio, TX · On-site

$93.80K - $121.30K/yr

... configuration, cooling, and downstream equipment. * Partner with R&D to scale up new TPU ... Develop and maintain process documentation, including work instructions, control plans, and ...

Xpel

Senior Process Engineer

San Antonio, TX · On-site

$93.80K - $121.30K/yr

... configuration, cooling, and downstream equipment. * Partner with R&D to scale up new TPU ... Develop and maintain process documentation, including work instructions, control plans, and ...

Merit

Engineer III

Pearland, TX

... downstream processing conditions. 4. Works independently on standard projects while assistance is ... Demonstrated experience with extrusion process development, optimization and troubleshooting.

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How much do downstream process development jobs pay per hour?

As of May 30, 2026, the average hourly pay for downstream process development in Texas is $31.38, according to ZipRecruiter salary data. Most workers in this role earn between $25.77 and $38.51 per hour, depending on experience, location, and employer.

What is a Downstream Process Development job?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What are the key skills and qualifications needed to thrive in the Downstream Process Development position, and why are they important?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

What are typical daily responsibilities for someone in Downstream Process Development?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.
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Downstream Process Development jobs near you

Scientist II, Downstream

Lonza

Houston, TX • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 25 days ago

Lonza rating

8.1

Company rating: 8.1 out of 10

Based on 39 frontline employees who took The Breakroom Quiz

32nd of 70 rated pharmaceutical

Job description

Scientist II, Downstream
Location: This is an on-site position located in Pearland, TX.
The purpose of this role is to work in a high performing, cross functional team with the goal of driving innovation in the development of scalable downstream processes related to the manufacture of therapeutic gene therapy products. The ideal candidate will be responsible for leading new process development and improving existing processes. The incumbent will independently design and coordinate the execution of experiments related to the purification of viral based gene therapy products, and be an excellent communicator.
What you will get:
A competitive compensation. In addition, below you will find a comprehensive summary of the benefits package we offer:
  • Performance-related bonus.
  • Medical, dental and vision insurance.
  • 401(k) matching plan.
  • Life insurance, as well as short-term and long-term disability insurance.
  • Employee assistance programs.
  • Paid time off (PTO).

Compensation for this role will be determined by the candidate's qualifications, skills, experience, and relevant knowledge.
What you will do:
  • Interacts with clients regarding process development scopes and tech transfer activities as well as data discussion and challenge resolutions.
  • Responsible for tech transfer to manufacturing following Lonza guidelines, provides ongoing supports as needed.
  • Designs and executes experiments, analyzes data. Authoring study protocols and reports. Maintains accurate & detailed records following Lonza's best documentation practices.
  • Contributes and supports scientific and engineering expertise toward the design and development of new downstream process ideas that support client product concepts.
  • Establish collaborative relationships and serve as SME to cross-functional groups (MSAT, MFG, QC, and PM).
  • Mentor and train junior colleagues.

What we are looking for:
  • PhD or MS in Life Sciences with focus on biology or bioengineering
  • Experience with development and optimization of viral or protein purification process including chromatography, filtration and formulation unit operations.
  • Experience with the technology transferring of viral or protein related downstream processes to cGMP manufacturing.
  • Experience or knowledge of analytical methods and in process controls commonly used in manufacturing processes.
  • Experience with late-stage process development for viral or protein related downstream process is highly desirable.

About Lonza:
At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone's ideas, big or small, have the potential to improve millions of lives, and that's the kind of work we want you to be part of.
Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you're ready to help turn our customers' breakthrough ideas into viable therapies, we look forward to welcoming you on board.
Ready to shape the future of life sciences? Apply now.

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