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Downstream Manufacturing Jobs (NOW HIRING)

Fladger Associates

Batch Record Coordinator

Fremont, CA · On-site

$21.25 - $29/hr

Ensures BioMES Electronic Batch Record (EBR) Modelers draft EBRs on-time for Downstream Manufacturing processing. * Maintains detailed Batch Record Delivery Schedule & Tracker for each product ...

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Downstream Manufacturing information

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How much do downstream manufacturing jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for downstream manufacturing in the United States is $24.95, according to ZipRecruiter salary data. Most workers in this role earn between $20.19 and $28.85 per hour, depending on experience, location, and employer.

What is downstream manufacturing?

Downstream manufacturing refers to the processes involved in the purification and formulation of products after the initial production phase, particularly in industries like biotechnology and pharmaceuticals. It typically includes steps such as separation, purification, and packaging of biomolecules or chemicals produced during upstream processes like fermentation or cell culture. The goal of downstream manufacturing is to ensure that the final product meets quality, safety, and regulatory standards before distribution to the market.

What are the key skills and qualifications needed to thrive in downstream manufacturing?

To thrive in Downstream Manufacturing, you need a solid understanding of biochemical processes, purification techniques, and quality control standards, often supported by a background in biotechnology, chemistry, or chemical engineering. Familiarity with process automation systems, chromatography equipment, and GMP (Good Manufacturing Practice) certification is commonly required. Attention to detail, strong problem-solving abilities, and effective teamwork are vital soft skills in this field. These skills ensure efficient production, product purity, regulatory compliance, and successful collaboration in biomanufacturing environments.

What are some common challenges faced in downstream manufacturing roles and how can they be addressed?

Professionals in Downstream Manufacturing often encounter challenges such as maintaining product purity, optimizing yield, and troubleshooting equipment issues during purification processes. Adapting to rapidly changing production schedules and ensuring compliance with strict regulatory standards can also pose difficulties. Effective solutions include thorough training in process controls, routine equipment maintenance, and strong collaboration with quality assurance and upstream teams to streamline workflows and address issues proactively.

What is the difference between Downstream Manufacturing vs Upstream Manufacturing?

AspectDownstream ManufacturingUpstream Manufacturing
FocusProcessing and finishing products after initial productionRaw material extraction and initial production processes
Work EnvironmentFactories, chemical plants, refineriesMining sites, raw material processing facilities
Common CertificationsProcess Safety Management, OSHA certificationsMining safety certifications, OSHA
Industry UsagePetroleum, chemicals, pharmaceuticalsMining, raw material extraction

Downstream Manufacturing involves processing and finishing products after initial production, often in chemical plants or refineries. Upstream Manufacturing focuses on raw material extraction and initial processing, such as mining or crude oil extraction. Both roles are essential in the supply chain but differ in their focus, environment, and certifications.

More about Downstream Manufacturing jobs

What states have the most Downstream Manufacturing jobs?

States with the most job openings for Downstream Manufacturing jobs include:

What are popular job titles for Downstream Manufacturing?

Popular job titles for Downstream Manufacturing:

Downstream Manufacturing jobs near you
Infographic showing various Downstream Manufacturing job openings in the United States as of September 2026, with employment types broken down into 50% Full Time, and 50% Contract. Highlights an 100% In-person job distribution, with an average salary of $51,890 per year, or $24.9 per hour.

SR MANUFACTURING ENGINEER - TUBING

Wilsonville, OR • On-site

TE Connectivity
Engineering Professional Services • 10K+ employees
Learn more about TE Connectivityexternal

$102K - $153K/yr

Full-time

Medical, Life, Retirement, PTO

Posted 17 days ago

TE Connectivity rating

7.6

Company rating: 7.6 out of 10

Based on 72 frontline employees who took The Breakroom Quiz

85th of 162 rated electronics manufacturers

Job description

At TE, you will unleash your potential working with people from diverse backgrounds and industries to create a safer, sustainable and more connected world.
Job Description:
Job Overview
Responsible for the design, development, validation, transfer, optimization, and sustained performance of polymer extrusion and downstream manufacturing processes used to produce medical tubing, catheter components, and medical heat-shrink products. The Senior Manufacturing Engineer will apply advanced knowledge of polymer materials, rheology, extrusion, thermal processing, heat-shrink expansion and recovery, and material-process-property relationships to develop stable, repeatable, and scalable manufacturing processes. The position will provide technical direction for new product introduction, manufacturing transfers, process troubleshooting, equipment and tooling development, process validation, and continuous improvement. This position works under general direction and exercises independent technical judgment when resolving complex manufacturing problems. The Senior Manufacturing Engineer will collaborate with Operations, Quality, Maintenance, Research and Development, Supply Chain, EHS, suppliers, customers, and other manufacturing sites. The individual may also train and coach operators, technicians, and less-experienced engineers.
Job Requirements
  • Lead the design, development, characterization, and optimization of polymer extrusion processes for tight-tolerance medical tubing and catheter-related components.
  • Develop and improve downstream manufacturing processes associated with medical heat-shrink tubing,
  • Develop a scientific understanding of the relationship between polymer properties, material condition, equipment configuration, tooling design, and process parameters.
  • Support the selection and evaluation of polymers used in medical tubing and heat-shrink applications, including PEBAX, nylon, polyurethane, polyethylene, other polyolefins, FEP, PFA, and related medical-grade materials.
  • Coordinate or perform testing of polymer materials and finished products.
  • Lead structured troubleshooting of extrusion and downstream manufacturing issues, including dimensional instability, wall-thickness variation, concentricity variation, surface defects, gels, contamination, pinholes, die lines, line breaks, surging, melt fracture, material degradation, expansion blowouts, slacking, uneven expansion, and recovery failures.
  • Apply engineering fundamentals, polymer science, rheology, heat transfer, statistical analysis, and equipment knowledge to differentiate material-, machine-, tooling-, method-, measurement-, and operator-related causes.
  • Lead root-cause investigations using appropriate methodologies such as DMAIC, A3, 8D, Design of Experiments, fishbone analysis, fault-tree analysis, and five-why analysis.
  • Develop, implement, and verify corrective and preventive actions associated with nonconformances, CAPAs, audit findings, manufacturing deviations, and customer complaints.
  • Plan, author, execute, and report equipment and process qualification activities, including Installation Qualification, Operational Qualification, and Performance Qualification.
  • Develop statistically and scientifically justified validation strategies, sampling plans, acceptance criteria, and process-capability requirements.
  • Execute or support Test Method Validation and measurement-system analysis for dimensional, mechanical, thermal, visual, and functional inspection methods.
  • Lead or support the transfer of products, equipment, tooling, and manufacturing technology between facilities.
  • Create and maintain Process Development Reports, technical reports, process specifications, setup sheets, Technical Instructions, work instructions, PFMEAs, control plans, validation protocols, validation reports, and troubleshooting guides.
  • Apply Design of Experiments, Statistical Process Control, process-capability analysis, regression, hypothesis testing, and other statistical methods using Minitab or equivalent software.
  • Identify and implement opportunities to improve safety, first-pass yield, process capability, throughput, labor efficiency, material utilization, equipment effectiveness, lead time, delivery performance, and Cost of Poor Quality.
  • Provide technical training and coaching to operators, technicians, and engineers on equipment setup, material behavior, process controls, troubleshooting, and standardized work.
  • Translate individual and subject-matter-expert knowledge into controlled, repeatable, and transferable manufacturing knowledge through written procedures, technical reports, images, videos, training materials, and practical demonstrations.

What your background should look like
  • Bachelor's degree in Polymer Engineering, Plastics Engineering, Materials Science and Engineering, Mechanical Engineering, Chemical Engineering, Manufacturing Engineering, Biomedical Engineering, or a related engineering discipline, with at least five years of relevant experience; or
  • Master's degree in a related engineering discipline with at least three years of relevant experience; or
  • Doctoral degree in a related engineering discipline; or
  • An equivalent combination of education and directly relevant technical experience.
  • Demonstrated hands-on experience developing, optimizing, or sustaining polymer extrusion processes.
  • Experience applying polymer rheology and material-property-processing relationships to manufacturing problems.
  • Experience with process validation, including IQ, OQ, and PQ activities.
  • Experience with Design of Experiments, Statistical Process Control, process capability, PFMEA, and root-cause analysis.
  • Experience investigating manufacturing nonconformances and implementing corrective actions.
  • Experience authoring technical reports, manufacturing instructions, validation documentation, and controlled specifications.
  • Working knowledge of ISO 13485, cGMP, and applicable medical-device quality-system requirements.
  • Proficiency with statistical analysis software such as Minitab.
  • Ability to work independently, manage multiple technical priorities, and lead cross-functional projects.
  • Strong written, verbal, analytical, and technical-presentation skills.

Competencies
Values: Integrity, Accountability, Inclusion, Innovation, Teamwork
ABOUT TE CONNECTIVITY
TE Connectivity plc (NYSE: TEL) is a global industrial technology leader creating a safer, sustainable, productive, and connected future. As a trusted innovation partner, our broad range of connectivity and sensor solutions enable the distribution of power, signal and data to advance next-generation transportation, energy networks, automated factories, data centers enabling artificial intelligence, and more.
Our more than 90,000 employees, including 10,000 engineers, work alongside customers in approximately 130 countries. In a world that is racing ahead, TE ensures that EVERY CONNECTION COUNTS. Learn more at www.te.com and on LinkedIn, Facebook, WeChat, Instagram and X (formerly Twitter).
COMPENSATION
• Competitive base salary commensurate with experience: $102,500 - $153,800 (subject to change dependent on physical location)
• Posted salary ranges are made in good faith. TE Connectivity reserves the right to adjust ranges depending on the experience/qualification of the selected candidate as well as internal and external equity.
• Total Compensation = Base Salary + Incentive(s) + Benefits
BENEFITS
• A comprehensive benefits package including health insurance, 401(k), disability, life insurance, employee stock purchase plan, paid time off and voluntary benefits.
EOE, Including Disability/Vets
IMPORTANT NOTICE REGARDING RECRUITMENT FRAUD
TE Connectivity has become aware of fraudulent recruitment activities being conducted by individuals or organizations falsely claiming to represent TE Connectivity. Please be advised that TE Connectivity never requests payment or fees from job applicants at any stage of the recruitment process. All legitimate job openings are posted exclusively on our official careers website at te.com/careers, and all email communications from our recruitment team will come only from actual email addresses ending in @te.com. If you receive any suspicious communications, we strongly advise you not to engage or provide any personal information, and to report the incident to your local authorities.

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