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Director Program Management Jobs in Brighton, MA

Alkermes

Director, Clinical Program Management

Waltham, MA · On-site

$220K - $235K/yr

... management, oversight, and execution of clinical programs in support of Alkermes' R&D portfolio ... direct reports fostering talent development, performance management, and a culture aligned with ...

Alkermes

Director, Clinical Program Management

Waltham, MA · Hybrid

$220K - $235K/yr

... management, oversight, and execution of clinical programs in support of Alkermes' R&D portfolio ... Provides oversight and support to direct reports fostering talent development, performance ...

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Showing results 41-60

All JobsProgram Management JobsDirector Program Management JobsDirector Program Management Jobs in Brighton, MA

Director Program Management information

See Brighton, MA salary details

$34.9K

$118.9K

$199.4K

How much do director program management jobs pay per year?

As of Aug 13, 2026, the average yearly pay for director program management in Brighton, MA is $118,851.00, according to ZipRecruiter salary data. Most workers in this role earn between $92,600.00 and $127,000.00 per year, depending on experience, location, and employer.

How does a director of program management typically collaborate with cross-functional teams to drive project success?

Directors of Program Management play a pivotal role in aligning cross-functional teams—such as engineering, product, marketing, and operations—to ensure that complex projects are delivered on time and within scope. They facilitate regular communication, resolve interdepartmental conflicts, and coordinate resources to keep everyone moving toward shared goals. This role often requires balancing strategic oversight with hands-on problem-solving, as well as fostering a collaborative culture that enables team members to contribute their expertise effectively. Strong relationship-building and negotiation skills are essential to proactively address challenges and maintain momentum across multiple initiatives.

What does a director of program management do?

A Director of Program Management oversees multiple projects or programs within an organization, ensuring they align with the company's strategic goals. They are responsible for setting priorities, allocating resources, and managing teams of project managers. This role involves coordinating across departments, mitigating risks, and ensuring that programs are delivered on time and within budget. Directors of Program Management also communicate with executive leadership and stakeholders to report on progress and outcomes.

What are the key skills and qualifications needed to thrive as a director of program management?

To thrive as a Director of Program Management, you need extensive experience in program and project management, a relevant degree (often in business or engineering), and proven leadership abilities. Familiarity with tools like Microsoft Project, Jira, and portfolio management software, along with certifications such as PMP or PgMP, is typically required. Exceptional communication, strategic thinking, and stakeholder management skills distinguish top performers in this role. These skills ensure the effective delivery of complex initiatives, alignment with organizational goals, and strong cross-functional collaboration.
What are the most commonly searched types of Program Management jobs in Brighton, MA? The most popular types of Program Management jobs in Brighton, MA are:
What job categories do people searching Director Program Management jobs in Brighton, MA look for? The top searched job categories for Director Program Management jobs in Brighton, MA are:
What cities near Brighton, MA are hiring for Director Program Management jobs? Cities near Brighton, MA with the most Director Program Management job openings:
Director Program Management jobs near you
Infographic showing various Director Program Management job openings in Brighton, MA as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 14% Part Time, and 4% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $118,851 per year, or $57.1 per hour.

Director, Program Management I & I Full Life Cycle

Monte Rosa Therapeutics, Inc

Boston, MA • On-site

$150K - $225K/yr

Full-time

Re-posted 14 days ago

Job description

Overview
The Associate Director of Program Management will serve as a strategic and operational leader for priority immunology and inflammation programs, driving assets from mid- to late-stage development through regulatory submission. This role is designed for a hands-on, agile leader who thrives in a fast-paced biotechnology environment and can rapidly translate evolving science into executable development strategy.
As a core member of the Program Team, the Director will partner closely with Clinical, Regulatory, CMC, Nonclinical, Biomarkers, Translational Sciences, and Commercial leaders to integrate strategy and execution across the full development lifecycle. This individual will ensure alignment to the Target Product Profile (TPP) and Integrated Development Plan (IDP), while enabling flexibility as data emerge and scientific understanding evolves.
Success in this role requires deep familiarity with immunology and inflammation drug development, comfort operating amid uncertainty, and the ability to balance scientific rigor with speed, capital efficiency, and enterprise priorities.
Responsibilities
  • Serve as a strategic and operational lead for one or more immunology/inflammation programs, ensuring alignment between clinical strategy, translational insights, and regulatory pathways.
  • Develop and maintain integrated, cross-functional development plans across clinical, regulatory, CMC, manufacturing, and translational functions.
  • Lead scenario planning exercises to evaluate alternative development pathways, indication sequencing, acceleration opportunities, and capital-efficient trade-offs.
  • Continuously pressure-test timelines and critical paths, proactively identifying opportunities to streamline execution without compromising quality.
  • Establish proactive risk identification and mitigation frameworks tailored to immunology/inflammation programs, including biomarker risk, patient heterogeneity, regulatory complexity, and competitive landscape shifts.
  • Lead high-quality risk discussions at the Global Program Team level with timely escalation of high-impact issues.
  • Develop contingency strategies for clinical, manufacturing, or regulatory inflection points.
  • Monitor program-level budget and resource health in alignment with corporate priorities.
  • Ensure clarity of functional accountabilities and decision rights in a lean, matrixed biotech structure.
  • Partner with functional leaders during long-range planning and portfolio prioritization exercises.
  • Build and maintain practical, real-time tracking tools (e.g., Smartsheet dashboards, integrated timelines, risk logs) that enable rapid visibility and decision-making.
  • Prepare concise, executive-ready materials that distill complex scientific and operational issues into clear recommendations.
  • Lead continuous improvement initiatives within Program Management to enhance agility, transparency, and execution discipline.

Qualifications
• 12+ years of experience in biotechnology or pharmaceutical drug development.
• Minimum 8 years of program/project management experience leading cross-functional development teams.
• Demonstrated experience advancing immunology and/or inflammation assets through Phase 2 and Phase 3 development.
• Experience preparing for and supporting major regulatory interactions (e.g., End-of-Phase 2 meetings, NDA/BLA submissions).
• Experience operating in small-to-mid-sized biotech environments where agility and hands-on leadership are required.
Education
• BS required; advanced degree (MS, PhD, or MBA) strongly preferred.
• PMP certification desirable but not required.
Technical & Leadership Capabilities
• Strong understanding of immunology and inflammation biology, clinical endpoints, biomarker strategy, and regulatory considerations.
• Deep knowledge of end-to-end drug development within a resource-conscious biotech setting.
• Demonstrated ability to lead through ambiguity and adapt strategy as data emerge.
• Proven success influencing senior stakeholders in a highly matrixed environment.
• Expertise in integrated planning, risk management, and scenario modeling.
• Strong executive presence with the ability to communicate complex scientific and operational topics clearly and concisely.
• Proficiency with modern project management and collaboration tools (e.g., Smartsheet, MS Project, Teams).
• Exceptional organizational skills with the ability to manage multiple interdependent workstreams simultaneously.
• High emotional intelligence, strong conflict resolution skills, and the ability to build trust across scientific and operational teams.
• Comfort operating with urgency, limited infrastructure, and evolving priorities typical of innovative biotech companies.

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