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$41K

$84.8K

$131K

How much do director process chemistry jobs pay per year?

As of Sep 11, 2026, the average yearly pay for director process chemistry in the United States is $84,782.00, according to ZipRecruiter salary data. Most workers in this role earn between $59,000.00 and $105,000.00 per year, depending on experience, location, and employer.

What does a director of process chemistry do?

A Director of Process Chemistry leads teams responsible for developing and optimizing chemical processes used in the production of pharmaceuticals or other chemicals. They oversee process development from laboratory scale to full manufacturing, ensuring efficiency, safety, and regulatory compliance. This role involves collaboration with R&D, manufacturing, and quality teams to deliver scalable and cost-effective chemical synthesis solutions. Directors also manage budgets, mentor staff, and may interact with regulatory agencies to support product approval.

What are the key skills and qualifications needed to thrive as a director of process chemistry?

A Director of Process Chemistry typically requires a Ph.D. in chemistry or chemical engineering, extensive experience in process development and scale-up, and a strong foundation in organic synthesis. Familiarity with analytical instrumentation, process safety systems, and regulatory compliance, as well as proficiency in software for data analysis and project management, are commonly expected. Exceptional leadership, communication, and problem-solving skills help foster innovation and guide multidisciplinary teams effectively. These competencies are vital for ensuring efficient, safe, and cost-effective chemical manufacturing processes that meet organizational goals and industry standards.

How does a director of process chemistry typically collaborate with cross-functional teams during drug development?

A Director of Process Chemistry works closely with teams such as Analytical Development, Formulation, Quality Assurance, and Regulatory Affairs to ensure smooth progression of drug candidates from lab to manufacturing scale. Collaboration involves regular meetings to align on project timelines, address technical challenges, and implement process improvements. This role often leads technology transfer discussions and troubleshooting sessions, ensuring process scalability and compliance with regulatory requirements. Effective communication and interdisciplinary teamwork are essential for success in this leadership position.

What is the difference between Director Process Chemistry vs Process Development Manager?

AspectDirector Process ChemistryProcess Development Manager
CredentialsAdvanced degree in Chemistry or Chemical Engineering, extensive industry experienceSimilar educational background, often with several years of industry experience
Work EnvironmentStrategic leadership, overseeing multiple projects and teamsHands-on process development, project management, and team coordination
Industry UsageUsed in pharmaceutical, chemical, and biotech industries for high-level oversightCommonly found in R&D and manufacturing settings for process optimization

The main difference is that the Director Process Chemistry focuses on strategic leadership and overall process chemistry direction, while the Process Development Manager handles day-to-day process development and project execution. Both roles require similar credentials but differ in scope and responsibilities.

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Director Process Chemistry jobs near you
Infographic showing various Director Process Chemistry job openings in the United States as of September 2026, with employment types broken down into 1% As Needed, 76% Full Time, 19% Part Time, 3% Contract, and 1% Nights. Highlights an 90% Physical, 2% Hybrid, and 8% Remote job distribution, with an average salary of $84,782 per year, or $40.8 per hour.

Director, Process Chemistry

Remote

Praxis Precision Medicines, Inc.
Biotechnology Research and Development • 51 - 200 employees
Learn more about Praxis Precision Medicines, Inc.external

$210K - $230K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 6 days ago

Job description

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.
The Opportunity
As Director of Process Chemistry, you will take the lead on drug substance activities for one or more projects within Praxis' portfolio of small molecule programs to drive forward both clinical and commercial readiness. You'll design products & processes that support clinical phase testing and then mature those processes through development to Commercial supply. Working intimately within the CMC and project teams under Agile management you'll identify requirements and constraints of our product to define a workplan that will lead to the successful manufacturing and creation of a data package to support commercial regulatory submissions.
This role is ideal for someone who thrives in a fast-moving, collaborative environment, where science meets ownership. You'll help define product requirements, anticipate challenges, and co-create practical, creative solutions that accelerate progress for patients in urgent need.
Primary Responsibilities
  • Leads the Process Chemistry Research and Development for one or more projects from early to late phase within Praxis.
  • Designs both early phase and late-phase/commercial drug substance process and then leads their demonstration from lab to pilot plant.
  • Provides chemistry and technical leadership throughout the lifecycle
  • Participates/leads activities to identify final API forms for pharmaceutical development.
  • Working closely with formulations, analytical, operations, engineering and quality, expectation to be integrated into the overall CMC team responsible for delivery of clinical and commercial drug substance to Praxis programs.
  • Identify, collaborate and lead external CRO, and CDMO organization(s) to achieve deliverables.
  • Analyze external experimental data to drive synthetic experimental plans at CROs and CDMO.
  • Authoring or co-authoring of regulatory submissions.
  • Define manufacturing strategy and execution, including GMP requirements and issue resolution.
  • Assessment and application of new trends and concerns in process development, quality and manufacturing to Praxis' products.
  • Manage quarterly budgeting of drug substance relevant activities.
  • Contributor to inventions that add value to Praxis and its patients while strengthening our intellectual property position.

Qualifications and Key Success Factors
  • Advanced degree or commensurate experience equivalent in Chemistry, Pharmaceutical Sciences, Engineering or related discipline.
  • Minimum of 12 years of industry experience in CMC specifically for small molecule drug substance.
  • A scientific track record or working knowledge in continuous processing, biocatalysis, catalysis, and/or high throughput experimentation desirable.
  • Strong knowledge of US and EU cGMP requirements and best practices relating to drug substances and drug products.
  • Strong knowledge of CMC development across all phases of drug development from initial regulatory filings through registration, validation and launch.
  • Experience in working with third-party CRO / CMO partners and associated service providers to develop and manufacturing pharmaceutical products.
  • Experience with salt/crystalline form selection preferred.
  • Experience with oligonucleotide chemistry is a plus
  • Demonstrates a high level of intellectual curiosity, innovation and creative problem solving with an entrepreneurial spirit; can thrive in an agile environment.
  • Excellent interpersonal and communication skills, with the ability to develop important relationships that include trust and encourage diversity in all its forms.
  • Highly organized and detail-oriented with a passion to deliver quality results.

Annualized Base Salary
$210,000-$230,000 USD
Compensation & BenefitsAt Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let's achieve the impossible together!
Company Overview
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.
Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

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