Are you skilled in large-scale oligonucleotide synthesis and interested in learning about RNAi discovery and development for impactful patient therapies? We want you on our team! Responsibilities:
Are you skilled in large-scale oligonucleotide synthesis and interested in learning about RNAi discovery and development for impactful patient therapies? We want you on our team! Responsibilities:
Senior Scientist, siRNA Synthesis
Worcester, MA · On-site
$91K - $124K/yr
Perform solid-phase oligonucleotide synthesis, deprotection, purification, and desalting of siRNA ... I or Senior Scientist II Additional Information Applicable only to applicants applying to a ...
Senior Scientist, siRNA Synthesis
Worcester, MA · On-site
$91K - $124K/yr
Perform solid-phase oligonucleotide synthesis, deprotection, purification, and desalting of siRNA ... I or Senior Scientist II Additional Information Applicable only to applicants applying to a ...
Advisor/Senior Advisor - Oligonucleotide Chemistry
Indianapolis, IN · On-site
$130K - $131K/yr
Are you skilled in large-scale oligonucleotide synthesis and interested in learning about RNAi discovery and development for impactful patient therapies? We want you on our team! Responsibilities:
Advisor/Senior Advisor - Oligonucleotide Chemistry
Indianapolis, IN · On-site
$130K - $131K/yr
Are you skilled in large-scale oligonucleotide synthesis and interested in learning about RNAi discovery and development for impactful patient therapies? We want you on our team! Responsibilities:
Senior Scientist, siRNA Synthesis
Worcester, MA · On-site
$91K - $124K/yr
Perform solid-phase oligonucleotide synthesis, deprotection, purification, and desalting of siRNA ... or Senior Scientist II Additional Information Applicable only to applicants applying to a ...
Quick apply
Senior Scientist, siRNA Synthesis
Worcester, MA · On-site
$91K - $124K/yr
Perform solid-phase oligonucleotide synthesis, deprotection, purification, and desalting of siRNA ... or Senior Scientist II Additional Information Applicable only to applicants applying to a ...
Senior Scientist, siRNA Synthesis
Worcester, MA · On-site
$109K/yr
Perform solid-phase oligonucleotide synthesis, deprotection, purification, and desalting of siRNA ... I or Senior Scientist II Additional Information Applicable only to applicants applying to a ...
Senior Scientist, siRNA Synthesis
Worcester, MA · On-site
$109K/yr
Perform solid-phase oligonucleotide synthesis, deprotection, purification, and desalting of siRNA ... I or Senior Scientist II Additional Information Applicable only to applicants applying to a ...
Senior Scientist: Automated DNA Synthesis & Microarrays
Memphis, TN · On-site
$104 - $186.16/hr
Key responsibilities include designing and operating the platform, supporting oligonucleotide ... synthesis, and developing high-throughput protocols. The ideal candidate has a bachelor's degree ...
Senior Scientist: Automated DNA Synthesis & Microarrays
Memphis, TN · On-site
$104 - $186.16/hr
Key responsibilities include designing and operating the platform, supporting oligonucleotide ... synthesis, and developing high-throughput protocols. The ideal candidate has a bachelor's degree ...
Senior Scientist, Oligonucleotide
Boston, MA · On-site
$145 - $155/hr
Synthesis & Modification:** Lead the design and execution of automated solid-phase synthesis of ... Senior Scientist, Oligonucleotide: Base pay range of $145,000 to $155,000+ bonus, equity and ...
Senior Scientist, Oligonucleotide
Boston, MA · On-site
$145 - $155/hr
Synthesis & Modification:** Lead the design and execution of automated solid-phase synthesis of ... Senior Scientist, Oligonucleotide: Base pay range of $145,000 to $155,000+ bonus, equity and ...
Senior Scientist, Oligonucleotide
Boston, MA · On-site
$99K - $135K/yr
Synthesis & Modification: Lead the design and execution of automated solid-phase synthesis of ... Senior Scientist, Oligonucleotide: Base pay range of $145,000 to $155,000+ bonus, equity and ...
Senior Scientist, Oligonucleotide
Boston, MA · On-site
$99K - $135K/yr
Synthesis & Modification: Lead the design and execution of automated solid-phase synthesis of ... Senior Scientist, Oligonucleotide: Base pay range of $145,000 to $155,000+ bonus, equity and ...
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation
Cambridge, MA · On-site
$100K - $136K/yr
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation #LI-Onsite Location: Cambridge ... Execute solid-phase synthesis of therapeutic oligonucleotides using automated DNA and RNA ...
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation
Cambridge, MA · On-site
$100K - $136K/yr
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation #LI-Onsite Location: Cambridge ... Execute solid-phase synthesis of therapeutic oligonucleotides using automated DNA and RNA ...
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation
Cambridge, MA · On-site
$100K - $136K/yr
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation #LI-Onsite Location: Cambridge ... Execute solid-phase synthesis of therapeutic oligonucleotides using automated DNA and RNA ...
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation
Cambridge, MA · On-site
$100K - $136K/yr
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation #LI-Onsite Location: Cambridge ... Execute solid-phase synthesis of therapeutic oligonucleotides using automated DNA and RNA ...
Senior Scientist, Oligonucleotide
South Boston, MA · On-site
$99K - $135K/yr
Synthesis & Modification: Lead the design and execution of automated solid-phase synthesis of ... Senior Scientist, Oligonucleotide: Base pay range of $145,000 to $155,000+ bonus, equity and ...
Senior Scientist, Oligonucleotide
South Boston, MA · On-site
$99K - $135K/yr
Synthesis & Modification: Lead the design and execution of automated solid-phase synthesis of ... Senior Scientist, Oligonucleotide: Base pay range of $145,000 to $155,000+ bonus, equity and ...
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation
Cambridge, MA · On-site
$100K - $136K/yr
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation #LI-Onsite Location: Cambridge ... Execute solid-phase synthesis of therapeutic oligonucleotides using automated DNA and RNA ...
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation
Cambridge, MA · On-site
$100K - $136K/yr
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation #LI-Onsite Location: Cambridge ... Execute solid-phase synthesis of therapeutic oligonucleotides using automated DNA and RNA ...
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation
Cambridge, MA · On-site
$94 - $174/hr
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation What if your expertise could ... Execute solid-phase synthesis of therapeutic oligonucleotides using automated DNA and RNA ...
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation
Cambridge, MA · On-site
$94 - $174/hr
Senior Scientist I or II, Oligonucleotide Chemistry and Innovation What if your expertise could ... Execute solid-phase synthesis of therapeutic oligonucleotides using automated DNA and RNA ...
Senior Scientist in Chemical Biology and Therapeutics
Memphis, TN · On-site
$104 - $186.16/hr
The Department of Chemical Biology and Therapeutics invites a Senior Scientist to lead the ... The role includes leading platform development, performing oligonucleotide synthesis, and applying ...
Senior Scientist in Chemical Biology and Therapeutics
Memphis, TN · On-site
$104 - $186.16/hr
The Department of Chemical Biology and Therapeutics invites a Senior Scientist to lead the ... The role includes leading platform development, performing oligonucleotide synthesis, and applying ...
Sr. Scientist, Electrochemical and Microarray DNA Synthesis
South San Francisco, CA · On-site
$125 - $150/hr
Sr. Scientist, Electrochemical and Microarray DNA Synthesis About this position Atlas Data Storage ... Experience in oligonucleotide microarray or pool synthesis is highly desirable * Strong ...
Sr. Scientist, Electrochemical and Microarray DNA Synthesis
South San Francisco, CA · On-site
$125 - $150/hr
Sr. Scientist, Electrochemical and Microarray DNA Synthesis About this position Atlas Data Storage ... Experience in oligonucleotide microarray or pool synthesis is highly desirable * Strong ...
Sr. Scientist, Electrochemical and Microarray DNA Synthesis
South San Francisco, CA · On-site
$160 - $210/hr
Sr. Scientist, Electrochemical and Microarray DNA Synthesis Company Overview Atlas Data Storage is ... Experience in oligonucleotide microarray or pool synthesis is highly desirable * Strong ...
Sr. Scientist, Electrochemical and Microarray DNA Synthesis
South San Francisco, CA · On-site
$160 - $210/hr
Sr. Scientist, Electrochemical and Microarray DNA Synthesis Company Overview Atlas Data Storage is ... Experience in oligonucleotide microarray or pool synthesis is highly desirable * Strong ...
Sr. Scientist, Electrochemical and Microarray DNA Synthesis
South San Francisco, CA · On-site
$125K - $150K/yr
We are seeking a Sr. Scientist, Electrochemical and Microarray DNA Synthesis who is ready to bring ... Experience in oligonucleotide microarray or pool synthesis is highly desirable * Strong ...
Sr. Scientist, Electrochemical and Microarray DNA Synthesis
South San Francisco, CA · On-site
$125K - $150K/yr
We are seeking a Sr. Scientist, Electrochemical and Microarray DNA Synthesis who is ready to bring ... Experience in oligonucleotide microarray or pool synthesis is highly desirable * Strong ...
Senior Manager, Process Development
Verona, WI · On-site
$120K - $135K/yr
The Position The role described herein is for a Senior Scientist to lead a team of chemists in the ... Develop and optimize solid phase oligonucleotide synthesis and downstream processes including ...
Senior Manager, Process Development
Verona, WI · On-site
$120K - $135K/yr
The Position The role described herein is for a Senior Scientist to lead a team of chemists in the ... Develop and optimize solid phase oligonucleotide synthesis and downstream processes including ...
The Senior Scientist, Oligo Chemistry is responsible for contributing hands-on scientific expertise ... Design, execute, and optimize oligonucleotide synthesis workflows with a strong focus on ...
The Senior Scientist, Oligo Chemistry is responsible for contributing hands-on scientific expertise ... Design, execute, and optimize oligonucleotide synthesis workflows with a strong focus on ...
Senior Manager, Process Development
Madison, WI · On-site
$120K - $135K/yr
The Position The role described herein is for a Senior Scientist to lead a team of chemists in the ... Develop and optimize solid phase oligonucleotide synthesis and downstream processes including ...
New
Quick apply
Senior Manager, Process Development
Madison, WI · On-site
$120K - $135K/yr
The Position The role described herein is for a Senior Scientist to lead a team of chemists in the ... Develop and optimize solid phase oligonucleotide synthesis and downstream processes including ...
New
Senior Oligonucleotide Synthesis information
See salary details
$25K - $37.6K
14% of jobs
$43.9K is the 25th percentile. Wages below this are outliers.
$37.6K - $50.2K
22% of jobs
$50.2K - $62.8K
9% of jobs
The median wage is $71.8K / yr.
$62.8K - $75.4K
7% of jobs
$75.4K - $88K
12% of jobs
$98.1K is the 75th percentile. Wages above this are outliers.
$88K - $100.5K
14% of jobs
$100.5K - $113.1K
9% of jobs
$113.1K - $125.7K
4% of jobs
$125.7K - $138.3K
3% of jobs
$138.3K - $150.9K
4% of jobs
$150.9K - $163.5K
2% of jobs
$25K
$80.3K
$163.5K
How much do senior oligonucleotide synthesis jobs pay per year?
What is a senior oligonucleotide synthesis specialist?
What are the key skills and qualifications needed to thrive as a senior oligonucleotide synthesis specialist?
What are some common challenges faced by senior oligonucleotide synthesis professionals, and how are they typically addressed in the lab environment?
What is the difference between Senior Oligonucleotide Synthesis vs Oligonucleotide Synthesis Technician?
| Aspect | Senior Oligonucleotide Synthesis | Oligonucleotide Synthesis Technician |
|---|---|---|
| Credentials | Bachelor's or higher in chemistry or related field, experience in oligonucleotide synthesis | Associate degree or relevant technical training, less experience required |
| Work Environment | Research labs, manufacturing facilities, overseeing synthesis processes | Hands-on synthesis work, equipment operation, quality checks |
| Responsibilities | Design protocols, supervise synthesis, troubleshoot issues | Prepare reagents, operate synthesizers, perform routine quality control |
In summary, Senior Oligonucleotide Synthesis roles involve higher-level responsibilities, supervision, and protocol development, while Oligonucleotide Synthesis Technicians focus on hands-on synthesis and equipment operation. Both roles are essential in the oligonucleotide manufacturing process but differ in experience requirements and scope of duties.
What cities are hiring for Senior Oligonucleotide Synthesis jobs?
Cities with the most Senior Oligonucleotide Synthesis job openings:
What are the most commonly searched types of Oligonucleotide Synthesis jobs?
The most popular types of Oligonucleotide Synthesis jobs are:
What states have the most Senior Oligonucleotide Synthesis jobs?
States with the most job openings for Senior Oligonucleotide Synthesis jobs include:
What job categories do people searching Senior Oligonucleotide Synthesis jobs look for?
The top searched job categories for Senior Oligonucleotide Synthesis jobs are:
- Vice President Scientist Process Chemistry
- Associate Scientist Process Chemistry
- Process Chemistry
- Senior Scientist Downstream Process Development
- Scientist Process Chemistry
- Virtual Medicinal Chemistry
- Associate Director Medicinal Chemistry
- Oligonucleotide Synthesis Scientist
- Nanoparticles Delivery Scientist
- Associate Process Development Scientist

$130K - $131K/yr
Full-time
Medical, Dental, Vision, Life, Retirement, PTO
Re-posted 6 days ago
Eli Lilly and Company rating
8.8
Based on 63 frontline employees who took The Breakroom Quiz
11th of 86 rated pharmaceutical
Job description
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 49,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Lilly is passionate about the discovery, development and commercialization of potential new medicines that will impact and improve the lives of patients. Lilly Genetic Medicines is an innovation-focused organization striving to identify, develop and apply the most cutting-edge technologies to deliver maximum benefit to our patients. Our agile and diverse team strives to operate as an autonomous 'biotech-like' company within the walls of Lilly.
The Lilly Genetic Medicines (LGM) Team is looking for a collaborative, creative, and energetic problem solver to join a multidisciplinary team at the front edge of innovation. They will join our fast-paced, interdisciplinary team as we utilize novel RNA/oligonucleotide based therapeutic modalities to enhance the Lilly portfolio. The successful applicant will utilize their knowledge and technical expertise to accelerate the core capabilities of large-scale oligonucleotide synthesis of internal RNAi-based clinical candidates. Are you skilled in large-scale oligonucleotide synthesis and interested in learning about RNAi discovery and development for impactful patient therapies? We want you on our team!
Responsibilities:
- Lead the Lilly Genetic Medicines discovery oligosynthesis scale-up team to accelerate Lilly RNAi Therapeutics from pre-clinical to clinical development
- Utilize comprehensive expertise in oligonucleotide synthesis methodologies to support Lilly Genetic Medicines and further develop internal capabilities and team growth through effective coaching, mentorship, and leadership.
- Collaborate with members of the RNAi discovery chemistry teams to validate and execute requirements for oligonucleotide synthesis from 150umol to 6mmol scales including communication of relevant information and results to project leads and/or cross functional organizations within Lilly to ensure seamless operation of the scale-up team.
- Actively support our efforts toward the discovery of lead drug candidates and lead at the interface with our CMC and Development teams to provide essential materials for key studies and effectively communicate technical insights to the development team.
- Demonstrate expertise in modern synthetic organic and nucleic acid chemistry, striving to improve methods, develop new technologies, and address synthetic oligonucleotide challenges across a diverse portfolio
- Oversee and prioritize the work of scale-up team members to meet critical timelines.
- Value diverse perspectives and experiences for effective solutions. Motivate team members to take initiative, own outcomes, and share expertise on complex technical challenges.
- Guide teams through unclear situations, adapt efficiently to changes, and evaluate and implement effective approaches to completing tasks.
Basic Qualifications:
- PhD degree in a relevant scientific discipline with 2+ years of experience (oligonucleotide synthesis experience, solid phase synthesis) or MS degree with 5+ years of experience (oligonucleotide synthesis experience, solid phase synthesis)
Preferred Qualifications:
- Experience in supervising a team of scientists to evaluate, refine and execute synthetic routes, technologies, and practices to deliver LGM portfolio
- Experience in troubleshooting and optimizing synthetic protocols on automated solid-phase synthesis instruments
- Experience with downstream processing of oligonucleotides including use of chromatographic purification and process TFF systems
- Ability to function within a highly interdisciplinary environment
- Excellent written and oral communication skills, good organizational skills, the ability to multitask, and lead a team to deliver on tight deadlines
- Confident, execution-focused, and team oriented with a desire to thrive in a fast-paced growing environment is a plus.
- Strong laboratory skills and experience with analytical instrumentation such as AKTA, Agilent LC-MS and UPLC, Vanquish LTQ, Water's QDA, etc
- Experience in developing new chromatographic methods (IEX/RP-HPLC, SPE, LC-MS).
- Experience in conjugation of novel ligands, including small molecules, peptides, and proteins to oligonucleotides at 5-25g scale
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$126,000 - $204,600Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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About Eli Lilly
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Eli Lilly, based in Indianapolis, IN, US, is one of the pioneers in the pharmaceutical industry with a rich history dating back to 1876. This global pharmaceutical company focuses on discovering, developing, manufacturing and selling pharmaceutical products in approximately 120 countries. The company's product categories include endocrinology, oncology, cardiovascular, neuroscience, and immunology. Having invested over $9 billion in research and development in the past decade, Eli Lilly is also committed to creating high-quality medicines that meet real needs. As a recipient of several awards and recognitions, Eli Lilly is known for its focus on life-saving research and drug development. Their mission is to make medicines that help people live longer, healthier, and more active lives.
Industry
Pharmaceutical product wholesalers
Company size
10,000+ Employees
Headquarters location
Indianapolis, IN, US
Year founded
1876