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Director Operational Risk Jobs in Antioch, CA (NOW HIRING)

... operations, etc. * Integrate risk insights into audit planning and business decision making. * SOX, ... of Directors and Audit Committee with clarity and credibility. * High level of integrity ...

... to reduce operational risk * Work cross-functionally with Product, Engineering, Support, and ... direct, hands-on experience operating cloud production environments * 3+ years of production ...

... Director, Insurance, Safety &Risk Management, the Risk Manager performs a broad range of complexprofessional and leadership duties associated with the safe, secure, andcompliant operation of the ...

... operations. This role is responsible for ensuring execution and implementation of safety programs ... Trains and conducts facility risk assessments and when needed, task-based hazard assessments.

... operations. This role is responsible for ensuring execution and implementation of safety programs ... Trains and conducts facility risk assessments and when needed, task-based hazard assessments.

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Director Operational Risk information

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$61.4K

$162.8K

$295.6K

How much do director operational risk jobs pay per year?

As of Aug 9, 2026, the average yearly pay for director operational risk in Antioch, CA is $162,797.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,000.00 and $190,400.00 per year, depending on experience, location, and employer.

What does a director of operational risk do?

A Director of Operational Risk is responsible for identifying, assessing, and mitigating risks that could impact an organization's operations. They develop risk management strategies, implement controls, and ensure compliance with relevant regulations. This role typically involves collaborating with different departments, reporting to senior management, and overseeing risk assessments and audits. The goal is to minimize losses and protect the organization from potential operational failures or external threats.

How does a director of operational risk typically collaborate with other departments to manage enterprise-wide risks?

A Director of Operational Risk works closely with teams across the organization—including compliance, internal audit, IT, and business unit leaders—to identify, assess, and mitigate potential risks. This collaboration often involves organizing risk assessments, sharing best practices, and developing response strategies for incidents. Regular cross-functional meetings and reporting are common, ensuring that risk management is integrated into day-to-day business operations. Effective communication and relationship-building are crucial for success in this role, as the Director must foster a risk-aware culture throughout the company.

What is the difference between Director Operational Risk vs Risk Manager?

AspectDirector Operational RiskRisk Manager
CredentialsTypically requires advanced degrees (e.g., MBA, Risk Management certifications)Often requires similar certifications but may have less emphasis on advanced degrees
Work EnvironmentStrategic, leadership-focused, overseeing risk frameworks across departmentsOperational, focused on identifying and mitigating specific risks within teams
Employer & Industry UsageCommon in banking, finance, insurance, and large corporationsFound across various industries including finance, healthcare, and manufacturing

The main difference is that the Director of Operational Risk typically holds a senior leadership role responsible for setting risk strategies and policies, while the Risk Manager focuses on implementing risk mitigation measures at the operational level. Both roles require relevant certifications and experience, but the Director position involves broader strategic oversight.

What are the key skills and qualifications needed to thrive as a director of operational risk, and why are they important?

A Director of Operational Risk needs deep knowledge of risk management frameworks, regulatory requirements, and operational processes, typically supported by a degree in finance, business, or a related field. Familiarity with risk assessment tools, data analytics platforms, and certifications such as FRM or CRM is highly valued. Strong leadership, analytical thinking, and effective communication are essential soft skills for guiding teams and influencing stakeholders. These competencies are crucial for identifying, assessing, and mitigating risks that could impact organizational objectives and regulatory compliance.
What are the most commonly searched types of Operational Risk jobs in Antioch, CA? The most popular types of Operational Risk jobs in Antioch, CA are:
What job categories do people searching Director Operational Risk jobs in Antioch, CA look for? The top searched job categories for Director Operational Risk jobs in Antioch, CA are:
What cities near Antioch, CA are hiring for Director Operational Risk jobs? Cities near Antioch, CA with the most Director Operational Risk job openings:

Director/Senior Director, Clinical Operations

5AM Ventures

Berkeley, CA

Full-time

Re-posted 4 days ago


Job description

Company Overview: 

At Renasant Bio, we are driven by a simple goal: to change what's possible for patients with kidney disease. ADPKD remains one of the most challenging areas in medicine, and we believe it requires bold thinking, rigorous science, and a team committed to doing things differently.

We're looking for individuals who bring both scientific rigor and creativity to hard problems, and who believe great work is built through respectful, direct collaboration. You communicate with honesty and transparency, adapt quickly as priorities evolve, and hold yourself-and others-to a high standard. Above all, you operate with urgency and purpose, grounded in the knowledge that patients are waiting.

Based at Bakar Labs in Berkeley, CA, we are advancing new therapies designed to make a meaningful difference for patients.

The Role: 

Renasant Bio is seeking a Director or Senior Director, Clinical Operations to build and lead the operational foundation of our clinical development organization as we advance multiple kidney disease programs toward the clinic.

The successful candidate will join at a stage where programs are transitioning from discovery and translational research into IND-enabling activities and first-in-human development. They will be responsible for building operational plans from the ground up, and determining how Renasant should structure its clinical execution capabilities as the company evolves.

This leader will help answer fundamental questions including:

  • What operational capabilities should be built internally versus outsourced?

  • Which CROs, specialty laboratories, and external vendors are best positioned to support our programs, and how should those partnerships be structured, managed, and scaled as the portfolio advances?

  • How should global clinical execution be designed and operationally managed for rare kidney diseases and genetically defined patient populations, including oversight of CROs, sites, and regional partners?

  • Which investigator networks, patient advocacy organizations, and clinical sites will be most critical to successful development, and how should those relationships be cultivated, coordinated, and leveraged throughout the clinical lifecycle?

The ideal candidate thrives in emerging biotechnology environments, enjoys creating structure where none exists, and has experience operationalizing novel therapies from preclinical development through early clinical execution.

Responsibilities

Create Clinical Infrastructure from the Ground Up

  • Design and implement scalable clinical operations processes, governance structures, vendor oversight models, and study management practices.

  • Establish the framework for how Renasant executes clinical trials as the organization grows.

  • Evaluate which functions should be maintained internally and which should be outsourced to CROs and specialized vendors.

  • Support future hiring plans and organizational design for Clinical Operations.

Drive Rare Disease and Genetic Testing Strategies

  • Support clinical studies involving genetically defined patient populations and genetic confirmation of diagnosis.

  • Develop operational approaches for patient identification, screening, and enrollment in rare disease populations.

  • Establish relationships with nephrology investigators, rare disease centers of excellence, patient advocacy organizations, and specialty testing partners.

  • Support global recruitment strategies where patient populations may be geographically dispersed.

CRO and Vendor Strategy

  • Lead selection, oversight, and performance management of CROs, central laboratories, genetic testing vendors, imaging vendors, and specialty providers.

  • Establish clear governance structures and accountability measures for external partners.

  • Ensure external partners function as extensions of the Renasant team while maintaining high standards of quality, speed, and execution.

Build the Bridge from Preclinical to Clinical

  • Serve as the primary Clinical Operations leader responsible for transitioning programs from preclinical and translational development into clinical execution.

  • Partner with DMPK, Toxicology, and Research teams to develop operationally feasible clinical development plans.

  • Identify operational risks, and execution challenges before studies enter the clinic.

  • Provide operational input into protocol development, patient identification approaches, and study feasibility.

Lead Early Clinical Development Execution

  • Build operational strategies for first-in-human and proof-of-concept studies.

  • Lead feasibility assessments, country selection, site identification, enrollment planning, and vendor selection activities.

  • Develop study timelines, budgets, risk mitigation plans, and execution strategies.

  • Oversee and execute study startup through database lock and study closeout.

Qualifications

Required Qualifications

  • Bachelor's degree in life sciences or related field; advanced degree preferred.

  • 10+ years of clinical operations experience (15+ for Senior Director)

  • Experience leading clinical studies from startup through database lock and study closeout.

  • Experience in rare disease, nephrology, ADPKD, genetic disease, or other specialized patient populations.

  • Experience with clinical studies requiring genetic testing, genetic confirmation of diagnosis, or genomics-driven patient identification.

  • Strong experience managing CROs and external vendors in outsourced operating models.

  • Demonstrated success leading study startup activities and global site activation efforts.

  • Experience developing study budgets, timelines, and operational risk management plans.

  • Strong knowledge of ICH-GCP, FDA, EMA, and global clinical trial regulations.

  • Excellent communication, leadership, and cross-functional collaboration skills.

Preferred Qualifications

  • Experience supporting global clinical trials, including sites outside the United States.

  • Experience building or scaling clinical operations functions within emerging biotechnology companies.

  • Experience supporting regulatory inspections and audit readiness activities.

  • Experience with decentralized or hybrid clinical trial models.

$210,000 - $270,000 a year
$210,000 - $275,000 per year
Director: $210,000 - $240,000
Senior Director: $240,000 - $275,000
 
Final compensation will be based on a candidate's qualifications, experience, and geographic location. Employees are also eligible for performance bonuses, equity participation and comprehensive health benefits.

We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.

Please note that we do not accept unsolicited resumes from recruitment agencies and external recruiters. No fees will be paid for such submissions.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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