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Director Of Program Management Jobs in Boston, MA

Alkermes

Director, Program Management Office

Waltham, MA · On-site

$212K - $240K/yr

The Program Manager will enable seamless execution of this dynamic development program by translating strategy into actionable plans, navigating complexity, and facilitating effective decision-making ...

Alkermes

Director, Program Management Office

Waltham, MA · Hybrid

$212K - $240K/yr

The Program Manager will enable seamless execution of this dynamic development program by translating strategy into actionable plans, navigating complexity, and facilitating effective decision-making ...

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All JobsOf Program Management JobsDirector Of Program Management JobsDirector Of Program Management Jobs in Boston, MA

Director Of Program Management information

See Boston, MA salary details

$34.8K

$118.5K

$198.8K

How much do director of program management jobs pay per year?

As of Sep 2, 2026, the average yearly pay for director of program management in Boston, MA is $118,477.00, according to ZipRecruiter salary data. Most workers in this role earn between $92,300.00 and $126,600.00 per year, depending on experience, location, and employer.

What does a director of program management do?

A director of program management implements strategic programs, monitors program performance, and evaluates project leaders for efficiency and accomplishments. As a director of program management, your job duties include overseeing the program management team, coordinating related projects, and finding solutions that improve performance at all levels within the company. To pursue a career as director of program management, you need a bachelor’s or master’s degree in project management, change management, business administration, or a related field, along with industry-specific knowledge and experience. Most employers also look for candidates with proven success in prior program management positions and demonstrated leadership skills.

What are the key skills and qualifications needed to thrive as a director of program management?

To thrive as a Director of Program Management, you need strong leadership, strategic planning, and project management expertise, typically supported by a bachelor's or master's degree and extensive experience managing complex programs. Familiarity with project management tools (like MS Project, Jira, or Asana), portfolio management systems, and certifications such as PMP or PgMP are often required. Exceptional communication, stakeholder management, and problem-solving skills set top candidates apart in this role. These capabilities are crucial for aligning cross-functional teams, achieving program objectives, and driving organizational success.

How does a director of program management typically collaborate with cross-functional teams to ensure program success?

A Director of Program Management works closely with various teams, such as product development, marketing, finance, and operations, to align program objectives and execution. They facilitate regular meetings to ensure transparency, address potential roadblocks, and foster a shared understanding of project goals. Effective Directors leverage their leadership and communication skills to build consensus and keep teams focused on deliverables, often acting as a bridge between executive leadership and project teams. This collaborative approach is essential for navigating complex projects and achieving organizational goals.

What is the difference between Director Of Program Management vs Program Manager?

AspectDirector Of Program ManagementProgram Manager
ResponsibilitiesOversees multiple projects and programs, aligns strategic goals, manages teamsManages individual projects, coordinates tasks, ensures project delivery
Required CredentialsBachelor's or Master’s in Business, Management, or related field; PMP or PgMP certifications often preferredBachelor's degree; PMP or similar certifications beneficial
Work EnvironmentStrategic planning, leadership meetings, cross-department collaborationProject planning, stakeholder communication, team coordination
Industry UsageCommon in large organizations, tech, finance, healthcareWidely used across industries for project execution

The main difference between a Director Of Program Management and a Program Manager lies in scope and leadership. Directors oversee multiple programs and set strategic direction, while Program Managers focus on executing individual projects. Both roles require strong project management skills and certifications, but Directors typically have more leadership responsibilities and strategic influence.

Is a director of program management a high position?

A director of program management is a senior leadership role responsible for overseeing multiple projects and teams within an organization. It is considered a high-level position that requires strong strategic, leadership, and communication skills, often reporting to executive management. The role typically involves significant responsibility and influence within a company.
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Director Of Program Management jobs near you
Infographic showing various Director Of Program Management job openings in Boston, MA as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 14% Part Time, and 3% Contract. Highlights an 90% Physical, 2% Hybrid, and 8% Remote job distribution, with an average salary of $118,477 per year, or $57 per hour.

Director, Program Management I & I Full Life Cycle

Monte Rosa Therapeutics, Inc

Boston, MA • On-site

$150K - $225K/yr

Full-time

Re-posted 4 days ago

Job description

Overview
The Associate Director of Program Management will serve as a strategic and operational leader for priority immunology and inflammation programs, driving assets from mid- to late-stage development through regulatory submission. This role is designed for a hands-on, agile leader who thrives in a fast-paced biotechnology environment and can rapidly translate evolving science into executable development strategy.
As a core member of the Program Team, the Director will partner closely with Clinical, Regulatory, CMC, Nonclinical, Biomarkers, Translational Sciences, and Commercial leaders to integrate strategy and execution across the full development lifecycle. This individual will ensure alignment to the Target Product Profile (TPP) and Integrated Development Plan (IDP), while enabling flexibility as data emerge and scientific understanding evolves.
Success in this role requires deep familiarity with immunology and inflammation drug development, comfort operating amid uncertainty, and the ability to balance scientific rigor with speed, capital efficiency, and enterprise priorities.
Responsibilities
  • Serve as a strategic and operational lead for one or more immunology/inflammation programs, ensuring alignment between clinical strategy, translational insights, and regulatory pathways.
  • Develop and maintain integrated, cross-functional development plans across clinical, regulatory, CMC, manufacturing, and translational functions.
  • Lead scenario planning exercises to evaluate alternative development pathways, indication sequencing, acceleration opportunities, and capital-efficient trade-offs.
  • Continuously pressure-test timelines and critical paths, proactively identifying opportunities to streamline execution without compromising quality.
  • Establish proactive risk identification and mitigation frameworks tailored to immunology/inflammation programs, including biomarker risk, patient heterogeneity, regulatory complexity, and competitive landscape shifts.
  • Lead high-quality risk discussions at the Global Program Team level with timely escalation of high-impact issues.
  • Develop contingency strategies for clinical, manufacturing, or regulatory inflection points.
  • Monitor program-level budget and resource health in alignment with corporate priorities.
  • Ensure clarity of functional accountabilities and decision rights in a lean, matrixed biotech structure.
  • Partner with functional leaders during long-range planning and portfolio prioritization exercises.
  • Build and maintain practical, real-time tracking tools (e.g., Smartsheet dashboards, integrated timelines, risk logs) that enable rapid visibility and decision-making.
  • Prepare concise, executive-ready materials that distill complex scientific and operational issues into clear recommendations.
  • Lead continuous improvement initiatives within Program Management to enhance agility, transparency, and execution discipline.

Qualifications
• 12+ years of experience in biotechnology or pharmaceutical drug development.
• Minimum 8 years of program/project management experience leading cross-functional development teams.
• Demonstrated experience advancing immunology and/or inflammation assets through Phase 2 and Phase 3 development.
• Experience preparing for and supporting major regulatory interactions (e.g., End-of-Phase 2 meetings, NDA/BLA submissions).
• Experience operating in small-to-mid-sized biotech environments where agility and hands-on leadership are required.
Education
• BS required; advanced degree (MS, PhD, or MBA) strongly preferred.
• PMP certification desirable but not required.
Technical & Leadership Capabilities
• Strong understanding of immunology and inflammation biology, clinical endpoints, biomarker strategy, and regulatory considerations.
• Deep knowledge of end-to-end drug development within a resource-conscious biotech setting.
• Demonstrated ability to lead through ambiguity and adapt strategy as data emerge.
• Proven success influencing senior stakeholders in a highly matrixed environment.
• Expertise in integrated planning, risk management, and scenario modeling.
• Strong executive presence with the ability to communicate complex scientific and operational topics clearly and concisely.
• Proficiency with modern project management and collaboration tools (e.g., Smartsheet, MS Project, Teams).
• Exceptional organizational skills with the ability to manage multiple interdependent workstreams simultaneously.
• High emotional intelligence, strong conflict resolution skills, and the ability to build trust across scientific and operational teams.
• Comfort operating with urgency, limited infrastructure, and evolving priorities typical of innovative biotech companies.

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