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How much do director downstream engineer jobs pay per year?

As of May 31, 2026, the average yearly pay for director downstream engineer in the United States is $111,632.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,500.00 and $132,500.00 per year, depending on experience, location, and employer.

What is the difference between Director Downstream Engineer vs Process Engineer?

AspectDirector Downstream EngineerProcess Engineer
CredentialsBachelor's/Master's in Chemical Engineering, extensive industry experienceBachelor's/Master's in Chemical or Process Engineering, relevant certifications
Work EnvironmentLeadership roles overseeing teams and projects in manufacturing plantsDesign, optimize, and troubleshoot processes in production facilities
Industry UsageCommon in large-scale chemical, oil & gas, and pharmaceutical companiesFound across similar industries, often in operational or technical roles

The main difference is that a Director Downstream Engineer typically holds a leadership position overseeing downstream processes, while a Process Engineer focuses on designing and improving specific processes. The Director role involves strategic planning and team management, whereas the Process Engineer is more hands-on with technical process optimization.

What cities are hiring for Director Downstream Engineer jobs? Cities with the most Director Downstream Engineer job openings:
What are the most commonly searched types of Downstream Engineer jobs? The most popular types of Downstream Engineer jobs are:
What states have the most Director Downstream Engineer jobs? States with the most job openings for Director Downstream Engineer jobs include:
What job categories do people searching Director Downstream Engineer jobs look for? The top searched job categories for Director Downstream Engineer jobs are:
Director Downstream Engineer jobs near you
Infographic showing various Director Downstream Engineer job openings in the United States as of May 2026, with employment types broken down into 94% Full Time, and 6% Contract. Highlights an 94% In-person, and 6% Remote job distribution, with an average salary of $111,632 per year, or $53.7 per hour.
Process Engineer - Biotech Downstream/Tech-Transfer (JP14390)

Process Engineer - Biotech Downstream/Tech-Transfer (JP14390)

3 Key Consulting

Cambridge, MA • On-site, Remote

$36 - $41/hr

Other

Posted 19 days ago

Job description

Job Title:Process Engineer - Biotech Downstream/Tech-Transfer (JP14390)
Location:Cambridge, MA. 02138 / Hybrid or Remote
Employment Type: Contract
Business Unit:Internal and External PE
Duration:1+ years (with likely extensions and/or conversion to permanent)
Rate: $36 - $41/ hour W2 with benefits
Posting Date:08/14/2025
Notes:This position can be Hybrid or Remote. Standard Business hours.
Local to Cambridge MA or Thousand Oaks CA would be nice but not necessary.
3 Key Consulting is hiring anEngineerfor a consulting engagement with our direct client, a leading global biopharmaceutical company.
Ideal candidate: 3+ years of industry experience, comfortable presenting. Biologics/ drug substance purification experience required (Chromatography, filtration, UFDF unit ops) Knowledge of purification processes/equipment; scale-up factors, process deviations, quality attributes. GMP experience is a huge plus.
Job Description:
Seeking a Process Development Engineer to join the Drug Substance Technology Engineering team at our Cambridge site. Providing strong process engineering/ technology transfer support of human therapeutic products in clinical development through commercial production. Our mission is to translate developmental processes to commercial reality for patients through scientific expertise and engineering innovation.
The Engineer will apply downstream process engineering knowledge in support of technology transfer and clinical/commercial drug substance manufacturing in both stainless and single-use formats. Will partner with manufacturing, quality, analytical, and bench scientists to support a highly dynamic technology transfer.
JOB RESPONSIBILITIES:
Under guidance of senior staff, the Engineer will perform the following:
  • Transfer purification processes for drug substance manufacturing and translate process improvements from the laboratory into manufacturing facilities
  • Provide technical support for successful scale-up, transfer of process technology, and for clinical and/or commercial manufacturing operation
  • Assist in troubleshooting clinical and commercial runs
  • Execute data trending and statistical process analysis
  • Support technical direction for process-related deviations, CAPAs, and change controls
  • Identify and support process-related operational excellence opportunities
  • Represent process development and collaborates with other functions such as Manufacturing, Quality, and Regulatory
Top Must Have Skills: Downstream Process, Tech Transfer, Scale-up
Basic Qualifications:
Master degree OR Bachelor degree and 2 years of experience OR Associate degree and 6 years of experience OR High school diploma / GED and 8 years of experience
Red Flags:
Predominant Upstream, Analytical or Drug Product experience
Interview process:
1on1 teams and Panel interview.
We invite qualified candidates to sendyour resume toresumes@3keyconsulting.com. Ifyou decide that you're not interested in pursuing this particular position, please feel free to take a look at the other positions on our websitewww.3keyconsulting.com/careers. You are also welcome to sharethis opportunity withanyone you think might be interested in applying for this role.

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