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Senior Director, Real-World Data Operations Lead

Eli Lilly and Company

Indianapolis, IN

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 22 days ago


Eli Lilly and Company rating

8.8

Company rating: 8.8 out of 10

Based on 63 frontline employees who took The Breakroom Quiz

11th of 86 rated pharmaceutical


Job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work-but it's work worth doing. If you're driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.


Purpose:

The Senior Director, RWD Operations Lead drives the strategy, execution,innovation,and continuous improvement of Lilly's real-world data ecosystem across therapeutic areas and enterprise data assets. This role ensures that RWD pipelines and processes are built,validated, and governed so that rawRWDare systematically evaluated, transformed, standardized, operationalized, and governedinto reusable,AI-readyassets that accelerate evidence generation at scale.

Equallythis leaderwilltranslate thestrategic direction and executionat the ground level,bringingdeep, hands-on RWDexpertiseto ensure that scientific requirements are faithfully reflected in infrastructure design and data engineering decisions - bridging the gap between research intent and technical build. This includes oversight of the construction of analytic datasets, ensuring, in collaboration with HEOR and related functions,they are built to specification, reproducible, and fit for regulatory-grade and publication-quality evidence generation.

This leader orchestrates cross-functional governance,establishesthe logical rules and frameworks forappropriate datause, and extends the vision for RWD value beyond HEOR to maximize enterprise-wide impact. Responsibilitiesalsoincludesupport of knowledge managementincluding, but not limited to,ownership of code list and algorithm creation and maintenance, ensuring a single source of truthof resources and a repositoryfor said informationthat enables high-quality, reproducible, and efficient evidence generation across Lilly's data portfolio. Critically, this role continuously scans for and incorporates emerging innovations- translating new capabilities into practical improvements that elevate the quality, speed, and scalability of Lilly's RWD operations.

The role sits at the core of the RWDARStransformation workstream, supporting futurestate team structure, operational governance, and execution excellence.

Primary Responsibilities:This job description is intended to provide a general overview of the job requirements at the time it was prepared.The job requirements of any position may change over time and may includeadditionalresponsibilities not specifically described in the job description.Consult with your supervisionregardingyouractualjob responsibilities and any related duties that may berequiredfor the position.

A. RWD Operational Excellence & Data Readiness

  • Lead the technicaland data integrityevaluation of raw RWD prior to acceptance and licensing, ensuring fitnessforuse, completeness,standardization,structure, and alignment with enterprise needsensuring all documentation issufficientand centralized.
  • Collaborate closely with RWD architect(s) and engineer(s)to translate scientific needs and intent intoenterprise RWDinfrastructure strategyand specificationsresolving pipeline bottlenecks and ensuring documentationmeets operational standards(SAPs, data dictionaries, audit trails).
  • Accelerateevidencegeneration by standardizing and transforming raw data into reusable, analysisready assets acrossdifferentbusinessunits.
  • Develop,execute, documentqualitycontrol frameworks thatqualify data completeness and ensureconsistent, reliable RWD operations at scale.
  • Lead withforward-thinking mindset toincorporatestrategicinnovation(AI)into RWD ecosystem operations.

B. Standardization of Coding Systems & Reusable RWD Assets

  • Own endtoend code list standardization, maintenance,stewardship,and hosting(e.g.ontology specifications, procedurecodes, andmedication codesincl.ICD10-CM,ICD-9, SNOMED-CTNDC, CPT/HCPC, LOINC,RxNorm).
  • Lead development and maintenance of reusable phenotyping algorithms, code libraries, and standardized data pipelinesand modular code toaccelerate studystartup.
  • Establish governance and documentation standards for RWD asset reuse across functions.

C. Governance & CrossFunctional Operations Management

  • Lead operational governance for the use of RWD, including access pathways, approval flows, stewardship processes, and compliance with enterprise standards.
  • Partnerwithdifferentstakeholderstoensure operational readiness of datasets, tools, and processes.
  • Support organizational change by clarifying new operational roles, interfaces, and futurestate workflows.

D. RWD Portfolio & Workflow Visibility Tools

  • Build tools and dashboards enablingstakeholderstogain rapid visibility into RWD sources- quality and densitystructures, limitations, and operational metadata.
  • Collaborate with RWD StrategyLeadto ensure visibility into current RWD assetsandpairingwith RWD/RWE studies and queriesto inform prioritization and resource planningfor data acquisition.
  • Operate with a research mindset to support building analytical, flexibleTA-specificcohortsto supportfast and consistentresearch

E. Training, Documentation, & Capability Building

  • Develop and deliver RWDsourcespecific trainings to ensure scientific, technical, and operational teams understand the structure, quality, and limitations of each asset.
  • Maintain and evolve documentation across pipelines, datasets, reusable components, and operational standards.

Minimum Qualification Requirements:

  • Masters degree (MS, MPH, PharmD, PhD) in a quantitative, data, orhealthrelatedfield.
  • Minimum of 3 years of RWDhands onexperiencewith:Healthcare data structures (claims, EHR, andmultimodalRWD, including linkedclinicalgenomic/omics datasets).
  • Minimum of 3 years experience of RWD Healthcare coding systems: ICD10, CPT, NDC, LOINC,RxNorm.

Additional Preferences:

  • Experience driving alignment and conflict resolution across technical and scientific teams.
  • Experience supporting organizational change and building operational frameworks.
  • Demonstrated ability to manage complex operational workflows across multiple stakeholders.
  • Strong analytical, organizational, and communication skills.
  • Strong strategic thinker at enterprise level and ability to collaborate with RWD architect,engineerand strategy roles.
  • Demonstrate leadership skillsininfluencingstakeholders to resolve conflicts
  • Demonstrate leadership inestablishingexternal partnership
  • Proficiencyin SQL, R, andRShiny, including dashboarding and operational tool development.
  • Familiarity with HEOR, medical, and statistical research workflows, including specification development,data quality assessment,studyexecution
  • Minimum of 2 years of direct people management experience, including leading, coaching, and developing team members preferred.

Additional Information:

  • Location: Indianapolis, IN is strongly preferred. Relocation assistance is available for qualified candidates. Remote work may be considered based on business needs and candidate qualifications.
  • Domestic and international travel may be necessary.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.


Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.


Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).


Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is

$169,500 - $248,600

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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About Eli Lilly

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Eli Lilly, based in Indianapolis, IN, US, is one of the pioneers in the pharmaceutical industry with a rich history dating back to 1876. This global pharmaceutical company focuses on discovering, developing, manufacturing and selling pharmaceutical products in approximately 120 countries. The company's product categories include endocrinology, oncology, cardiovascular, neuroscience, and immunology. Having invested over $9 billion in research and development in the past decade, Eli Lilly is also committed to creating high-quality medicines that meet real needs. As a recipient of several awards and recognitions, Eli Lilly is known for its focus on life-saving research and drug development. Their mission is to make medicines that help people live longer, healthier, and more active lives.

Industry

Pharmaceutical product wholesalers

Company size

10,000+ Employees

Headquarters location

Indianapolis, IN, US

Year founded

1876