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Director Cell Line Development Jobs (NOW HIRING)

Systimmune

Senior Scientist, Cell Science

Redmond, WA · On-site

$90K - $140K/yr

Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression. * Perform cell culture experiments involving mammalian ...

SystImmune, Inc

Senior Scientist, Cell Science

Redmond, WA · On-site

$90K - $140K/yr

Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression. * Perform cell culture experiments involving mammalian ...

ATUM

Senior Director of Program Management

Newark, CA · On-site

$170K - $200K/yr

Senior Director of Program Management | ATUM ATUM is a leader in cell line development, gene synthesis, and protein engineering. We are seeking a strategic Director of Program Management to spearhead ...

AbbVie

Senior Scientist I, Host Cell Engineering

Worcester, MA · On-site

$91K - $124K/yr

In addition, the successful candidate will enable the Biologics' pipeline through production cell line development and characterization and collaboration on cross-functional teams. Experience with ...

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Director Cell Line Development information

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How much do director cell line development jobs pay per year?

As of Jun 14, 2026, the average yearly pay for director cell line development in the United States is $82,598.00, according to ZipRecruiter salary data. Most workers in this role earn between $55,000.00 and $97,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Director Cell Line Development, and why are they important?

To excel as a Director Cell Line Development, you need advanced knowledge in cell biology, molecular biology, and bioprocessing, often backed by a Ph.D. and significant industry experience. Expertise with technologies such as CRISPR, high-throughput screening, cell culture automation systems, and regulatory standards like GMP is essential. Strong leadership, strategic planning, and effective communication are vital soft skills for guiding teams and collaborating across departments. These competencies ensure the efficient creation of robust cell lines critical for biologics development and organizational success.

What does a Director of Cell Line Development do?

A Director of Cell Line Development leads teams responsible for creating and optimizing cell lines used in the production of biopharmaceutical products, such as therapeutic proteins and antibodies. This role involves overseeing scientific strategy, ensuring regulatory compliance, and collaborating with cross-functional teams to meet project goals. Directors also provide technical guidance, manage budgets, and contribute to the development of new technologies and processes. Their work is critical in ensuring high-yield, stable, and safe cell lines for large-scale manufacturing.

What are the primary challenges a Director of Cell Line Development faces when overseeing multiple projects simultaneously?

A Director of Cell Line Development often manages several projects at different stages, which requires balancing timelines, resources, and technical challenges. Coordinating cross-functional teams—such as upstream process development, analytical, and quality assurance groups—can be complex, especially when each project has unique scientific hurdles and regulatory requirements. Effective communication, prioritization, and risk mitigation are key skills needed to ensure projects progress smoothly and meet critical milestones. Additionally, maintaining up-to-date knowledge of evolving technologies and regulatory guidelines is essential to lead teams successfully.
What cities are hiring for Director Cell Line Development jobs? Cities with the most Director Cell Line Development job openings:
What are the most commonly searched types of Cell Line Development jobs? The most popular types of Cell Line Development jobs are:
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Director Cell Line Development jobs near you
Infographic showing various Director Cell Line Development job openings in the United States as of June 2026, with employment types broken down into 1% Internship, 80% Full Time, 13% Part Time, 5% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $82,598 per year, or $39.7 per hour.
Senior Scientist, Cell Science

Senior Scientist, Cell Science

Systimmune

Redmond, WA • On-site

$90K - $140K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 17 days ago

Job description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
 

The Senior Scientist in the Cell Science Department is responsible for the development and optimization of CHO-based processes for the production of biotherapeutics. This role requires broad expertise and the ability to contribute to both drug discovery and development projects. A strong interest in bench work and hands-on experience with mammalian cell culture is essential.
This position requires a full-time onsite presence at our Redmond, WA location.
Responsibilities:
  • Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression.
  • Perform cell culture experiments involving mammalian cells (e.g., CHO cells) under sterile, aseptic conditions.
  • Develop and optimize expression systems, including promoters, selection markers, and gene amplification strategies for high-yield production.
  • Screen and characterize clones for productivity, stability, growth characteristics, and product quality attributes using molecular and biochemical assays.
  • Collaborate with project teams and downstream process development scientists to execute protocols, experimental plans, critical production batches, and technology transfers.
  • Manage and prioritize multiple projects while supporting and coordinating with other departments to advance company objectives and develop scalable, robust culture processes.
  • Write and review Standard Operating Procedures (SOPs) and technical reports for regulatory filings.
  • Prepare process transfer documents and cGMP documentation to support the successful implementation of process technologies in clinical and commercial manufacturing operations.
  • Collaborate with R&D and the manufacturing team in China, participating in meetings and providing technical support as needed.
  • Availability to work weekend and holiday shifts, as required.
  • Perform other duties as assigned.


Qualifications:

  • Ph.D. in Cell Biology or a related field, with 5+ years of relevant experience in the pharmaceutical or biotechnology industry.
  • Strong scientific background in recombinant protein expression, cell line development, cellular metabolism, and media optimization.
  • Experience in both early- and late-stage bioreactor operations, mammalian stable cell line development, and upstream process development is preferred.
  • Demonstrated expertise in advanced technologies for cell line development, with a focus on antibody production.
  • Strong knowledge of FDA regulations and other global health authority requirements related to Investigational New Drug (IND) applications, particularly those concerning single stable clone selection and characterization.
  • Excellent written, verbal, and interpersonal communication skills.
  • Proven ability to perform effectively under pressure, meet tight deadlines, and adapt to shifting project priorities and requirements.
  • Experience with high-throughput automated workstations for clone selection is highly desirable.
Compensation and Benefits:
The expected base salary range for this position is $90,000 - $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.
 

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