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Director Applied Technology Jobs (NOW HIRING)

Redesign's technology practice combines a frontier applied AI lab with deep healthtech investing ... About the Job: We're hiring an ambitious, self-initiated, product-minded Senior Director, Applied ...

Director, Applied AI

New York, NY ยท On-site

$225K - $265K/yr

Who you are Metropolis is seeking a Director of Applied AI to lead our newly formed Applied AI ... Show a track record of driving organizational change through technology and ensuring tools are ...

Who you are Metropolis is seeking a Director of Applied AI to lead our newly formed Applied AI ... Show a track record of driving organizational change through technology and ensuring tools are ...

Who you are Metropolis is seeking a Director of Applied AI to lead our newly formed Applied AI ... Show a track record of driving organizational change through technology and ensuring tools are ...

Director, Applied AI

New York, NY ยท On-site

$225K - $265K/yr

Who you are Metropolis is seeking a Director of Applied AI to lead our newly formed Applied AI ... Show a track record of driving organizational change through technology and ensuring tools are ...

Director, Applied AI Product Manager: At BNY, our culture allows us to run our company better and ... Every day, our teams harness cutting-edge AI and breakthrough technologies to collaborate with ...

Director, Applied AI Product Manager

Manhattan, NY ยท On-site

$256K - $269K/yr

Director, Applied AI Product Manager: At BNY, our culture allows us to run our company better and ... Every day, our teams harness cutting-edge AI and breakthrough technologies to collaborate with ...

Director, Applied AI

Seattle, WA ยท On-site

$225K - $265K/yr

Who you are Metropolis is seeking a Director of Applied AI to lead our newly formed Applied AI ... Show a track record of driving organizational change through technology and ensuring tools are ...

Director, Applied AI

Seattle, WA ยท On-site

$225K - $265K/yr

Who you are Metropolis is seeking a Director of Applied AI to lead our newly formed Applied AI ... Show a track record of driving organizational change through technology and ensuring tools are ...

Technical Skills & Tech Stack: Strong working knowledge of generative AI, machine learning, data ... Demonstrated ability to lead and develop technical teams, direct senior individual contributors ...

As a key member of our AI Technology, Innovation & Delivery team, this role leads Regenerons ... The Executive Director, Applied AI sets direction across four interconnected domains Agentic AI ...

As a key member of our AI Technology, Innovation & Delivery team, this role leads Regeneron ... The Executive Director, Applied AI sets direction across four interconnected domains -- Agentic AI ...

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Director Applied Technology information

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$43.5K

$116.8K

$201K

How much do director applied technology jobs pay per year?

As of Jul 10, 2026, the average yearly pay for director applied technology in the United States is $116,795.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,500.00 and $141,000.00 per year, depending on experience, location, and employer.

What does a Director of Applied Technology do?

A Director of Applied Technology oversees the implementation and integration of technological solutions within an organization to support its business goals. They lead teams of IT professionals, collaborate with other departments to identify technology needs, and ensure that new systems and software are effectively adopted. Their role often involves strategic planning, project management, and staying current with emerging technologies to keep the organization competitive. They also manage budgets, vendor relationships, and ensure compliance with relevant regulations.

What are some common challenges faced by a Director of Applied Technology, and how can they be addressed?

Directors of Applied Technology often encounter challenges such as balancing rapidly evolving technological trends with organizational goals, integrating new systems with legacy infrastructure, and fostering cross-departmental collaboration. Addressing these challenges requires proactive communication, staying updated with industry advancements, and building strong relationships with both technical and non-technical stakeholders. Emphasizing continuous learning and encouraging an agile mindset within the team can also help navigate frequent changes and drive innovation effectively.

What are the key skills and qualifications needed to thrive as a Director of Applied Technology, and why are they important?

To thrive as a Director of Applied Technology, you need deep expertise in technology strategy, project management, and a strong background in computer science or engineering, often supported by an advanced degree. Familiarity with enterprise software, cloud platforms, data analytics tools, and relevant certifications such as PMP or AWS Certified Solutions Architect is typically required. Leadership, strategic thinking, and effective communication are crucial soft skills for driving innovation and managing cross-functional teams. These abilities ensure successful technology adoption, align IT initiatives with business goals, and foster a culture of continuous improvement.
More about Director Applied Technology jobs
What cities are hiring for Director Applied Technology jobs? Cities with the most Director Applied Technology job openings:
What are the most commonly searched types of Applied Technology jobs? The most popular types of Applied Technology jobs are:
What states have the most Director Applied Technology jobs? States with the most job openings for Director Applied Technology jobs include:
Infographic showing various Director Applied Technology job openings in the United States as of July 2026, with employment types broken down into 75% Full Time, 23% Part Time, 1% Temporary, and 1% Contract. Highlights an 90% Physical, 2% Hybrid, and 8% Remote job distribution, with an average salary of $116,795 per year, or $56.2 per hour.
Director, Applied AI

Director, Applied AI

Denali Therapeutics

South San Francisco, CA โ€ข On-site

$204K - $265K/yr

Full-time

Medical, Retirement

Posted 17 days ago


Job description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Denali is seeking a Director, Applied AI to build and lead Denali's applied-AI practice, bringing measurable, AI-driven efficiency to how Denali operates. At Denali, Applied AI is the practical implementation of artificial intelligence to solve specific, real-world problems and deliver tangible business value. Reporting to the VP of Information Technology and partnering directly with senior leaders across the company, this individual sets strategy for where and how applied AI creates value, then builds it by shipping solutions directly and working with partners to scale. A successful candidate is a recognized expert in the practical application of AI, with command of the discipline from idea to production, this person sets the standard for how AI is put to work at Denali and raises the ability of teams across the company to do the same. The role pairs deep, current AI engineering skills with the judgment to operate in a regulated environment and the presence to demonstrate return on investment to leadership.
Key Accountabilities / Core Job Responsibilities
  • Serve as Denali's recognized expert on the practical application of AI, setting standards for how AI is applied across the company, advising teams and leadership, and raising their ability to apply it well in their own work.
  • Own and drive Denali's applied-AI strategy, determining where AI has a role, choosing approaches, and setting priorities alongside leadership and teams.
  • Partner with leaders across the company to find the problems worth solving, which include high-volume, workflow-specific work that goes beyond individual AI tools.
  • Design, prototype, and build AI solutions hands-on, moving quickly from idea to production and getting directly into the data, models, and workflows.
  • Deliver measurable efficiency gains and use the results to guide where to focus AI next.
  • Bring strategy, progress, wins, risks, and tradeoffs to senior leadership to drive investment and prioritization decisions.
  • Work hand in hand with Legal, Quality, and Regulatory to enable a compliant paths to production for safe AI use.
  • Drive adoption of what gets built and establish the repeatable methods and playbooks that let applied AI scale across the company.

Qualifications/Skills
  • Bachelor's or Master's degree in a technical field such as computer science, artificial intelligence, data science, or engineering, or an equivalent combination of education and experience.
  • 10+ years building and delivering solutions, with applied AI/ML at the center of recent, hands-on work: fluent in Python and hands-on building generative AI / LLM applications (RAG, fine-tuning, agentic workflows) through to production.
  • Direct experience in a regulated life sciences industry (pharma, biotech, or medical devices), including GxP, and AI frameworks such as ISO/IEC 42001 and NIST AI RMF.
  • Demonstrated experience driving cross-functional outcomes as a senior individual

Salary Range: $204,000.00 to $265,000.00 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers
This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.