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Contract Senior Clinical Research Associate Jobs

ICON

Senior Clinical Research Associate

Chicago, IL · On-site +1

$110K - $138K/yr

Senior Clinical Research Associate - Oncology Phase I - Chicago ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments ...

Icon plc

Senior Clinical Research Associate

San Diego, CA · Hybrid

$110K - $138K/yr

Senior Clinical Research Associate - Oncology - Southern California ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and ...

Icon plc

Senior Clinical Research Associate

Miami, FL · Hybrid

Senior Clinical Research Associate - Oncology Phase I - Miami, FL ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments ...

New

Icon plc

Senior Clinical Research Associate

Washington, DC · Hybrid

$110K - $138K/yr

Senior Clinical Research Associate - Oncology - Washington DC ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to ...

ICON

Senior Clinical Research Associate

Los Angeles, CA · On-site +1

$110K - $138K/yr

Senior Clinical Research Associate - Oncology - Los Angeles, CA ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments ...

WEP Clinical

Senior Clinical Research Associate

The WEP Clinical Senior Clinical Research Associate (Senior CRA) oversees all aspects of clinical monitoring and site management in compliance with GCP, global regulatory requirements, and WEP ...

Emmes

Senior Clinical Research Associate

Rockville, MD · On-site +1

Overview Senior Clinical Research Associate US remotely and on-site (80% travel) Emmes Group: Building a better future for us all. Emmes Group is transforming the future of clinical research ...

Getinge

Sr. Clinical Research Associate

Boston, MA · On-site

$125K/yr

The Senior Clinical Research Associate is responsible for oversight of the prospective randomized clinical studies conducted by Paragonix Technologies. This position is responsible for managing ...

Getinge

Sr. Clinical Research Associate

Boston, MA · Hybrid

$125K/yr

The Senior Clinical Research Associate is responsible for oversight of the prospective randomized clinical studies conducted by Paragonix Technologies. This position is responsible for managing ...

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Contract Senior Clinical Research Associate information

See salary details

$36K

$94.3K

$143.5K

How much do contract senior clinical research associate jobs pay per year?

As of Aug 8, 2026, the average yearly pay for contract senior clinical research associate in the United States is $94,314.00, according to ZipRecruiter salary data. Most workers in this role earn between $62,500.00 and $128,000.00 per year, depending on experience, location, and employer.

What is a contract senior clinical research associate?

A Contract Senior Clinical Research Associate (CRA) is an experienced clinical research professional who works independently or through an agency on a contract basis, rather than as a permanent employee. Their primary role is to monitor clinical trials, ensuring that studies are conducted according to protocol, regulatory requirements, and Good Clinical Practice (GCP) guidelines. Senior CRAs have advanced knowledge of clinical trial processes and often oversee multiple sites or junior staff. They are responsible for reviewing data, managing documentation, and acting as a liaison between the study sponsor and the investigative sites. Contract positions offer flexibility and variety, but may require more travel and self-management.

What skills and qualifications are needed to thrive as a contract senior clinical research associate?

To thrive as a Contract Senior Clinical Research Associate, you need comprehensive knowledge of clinical trial processes, GCP/ICH guidelines, and relevant regulatory requirements, typically supported by a life sciences degree and several years of monitoring experience. Familiarity with Electronic Data Capture (EDC) systems, trial management software, and certifications like ACRP or SOCRA are commonly required. Exceptional organizational skills, attention to detail, and effective communication make someone stand out in this role. These skills and qualities are vital to ensure protocol compliance, high data quality, and successful collaboration across study sites.

How does a contract senior clinical research associate typically collaborate with study sites and sponsors during a clinical trial?

As a Contract Senior Clinical Research Associate (CRA), you play a key liaison role between study sites and sponsors. You are responsible for monitoring site performance, ensuring protocol compliance, and addressing any issues that arise during the trial. Regular communication with site staff and sponsor representatives is essential, often involving site visits, remote monitoring, and reporting. Effective collaboration helps maintain study integrity, ensures regulatory requirements are met, and facilitates the timely progression of the clinical trial.

What is the difference between Contract Senior Clinical Research Associate vs Clinical Research Associate?

AspectContract Senior Clinical Research AssociateClinical Research Associate
CredentialsBachelor's degree, relevant certifications, experience in clinical trialsBachelor's degree, entry-level certifications often sufficient
Work EnvironmentContract basis, often in multiple sites or projects, possibly remoteFull-time or part-time, typically at a single site or sponsor location
Employer & Industry UsagePharmaceutical companies, CROs, biotech firms, project-basedPharmaceutical companies, CROs, hospitals, research sites

The Contract Senior Clinical Research Associate typically has more experience, handles complex trial aspects, and works on a contractual basis. The Clinical Research Associate is often an entry-level or mid-level role focused on site monitoring and data collection. Both roles are essential in clinical trials but differ mainly in experience level and employment type.

More about Contract Senior Clinical Research Associate jobs
What cities are hiring for Contract Senior Clinical Research Associate jobs? Cities with the most Contract Senior Clinical Research Associate job openings:
What states have the most Contract Senior Clinical Research Associate jobs? States with the most job openings for Contract Senior Clinical Research Associate jobs include:
What job categories do people searching Contract Senior Clinical Research Associate jobs look for? The top searched job categories for Contract Senior Clinical Research Associate jobs are:
Contract Senior Clinical Research Associate jobs near you
Infographic showing various Contract Senior Clinical Research Associate job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 71% Full Time, 18% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $94,314 per year, or $45.3 per hour.

Senior Clinical Research Associate

ICON

Chicago, IL • On-site, Remote

$110K - $138K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 12 days ago

Job description

Senior Clinical Research Associate - Oncology Phase I - Chicago
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
The Sr. Clinical Research Associate (Sr. CRA) will be responsible for performing investigative site management and monitoring activities throughout the clinical trial lifecycle. This Sr. CRA role will support the client's Oncology clinical trials to ensure data integrity, subject safety, and inspection readiness at the clinical investigative sites.
Responsibilities:
  • Perform site management activities to support the client's Oncology site success and maintain a continuous state of inspection readiness
  • Act as the primary contact and facilitate efficient communications between the client's clinical trial team and the sites
  • Perform remote and on-site monitoring/co-monitoring visits (Site Qualification Visits, Site Initiation Visits, Interim Monitoring Visits and Close-Out Visits) to ensure data integrity and subject safety in the client's trials
  • May perform oversight activities to assess monitoring quality and train/mentor less experienced CRAs
  • Promptly document monitoring activities and submit/approve visit reports
  • Manage site essential document collection and TMF reconciliation with site files
  • Support sites with local Institutional Review Board (IRB)/Ethics Committee (EC) submissions and confirm approvals
  • Regularly review site Key Risk Indicator (KRI) metrics, issues and action items to detect trends and ensure prompt resolution
  • Independently determine root causes and develop/implement site Corrective Action and Preventive Action (CAPA) plans
  • Deliver training to ensure sites comply with the protocol, Standard Operating Procedures (SOPs), Good Clinical Practices (GCPs) and regulations
  • Support sites and the client's regulatory inspections
  • Contribute to site identification; drive site feasibility and qualification progress; and support site activation activities
  • Lead site engagement initiatives and foster relationships with key Oncology sites and networks

Qualifications
  • Bachelor's degree (scientific field preferred)
  • 5+ years monitoring clinical trials independently conducting on-site and remote monitoring visits. Atleast 2 years monitoring solid tumor clinical trials.
  • 1+ years early development trial experience
  • Solid tumor clinical trial experience is required
  • Experience utilizing Veeva systems is highly preferred
  • Demonstrated experience developing/maintaining site relationships and securing compliance
  • Expertise in GxPs and Oncology monitoring techniques (including Risk-Based Monitoring) and terminology
  • Experience collaborating with sites from initial engagement through close-out phases
  • Experience activating sites
  • Experience training site staff
  • Experience supporting sites and/or sponsors in regulatory inspections
  • Experience working within a Functional Services (or in-house) monitoring model is preferred
  • Willing to travel up to 50%

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Salary Range
$110,520.00-$138,150.00
Are you a current ICON Employee? Please click here to apply

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