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Clinical Trial Operations Jobs (NOW HIRING)

Solomon Page

Clinical Trial Manager

Basking Ridge, NJ · On-site

$100 - $120/hr

We are seeking a hands-on Clinical Trial Manager to oversee clinical trial operations and drive study execution from start-up through closeout. This role requires strong sponsor management skills ...

Prometrika LLC

Clinical Trial Manager

Cambridge, MA · On-site

$140K - $168K/yr

Manage the operational aspects of clinical trials (e.g., study management, site monitoring and management, trial master file (TMF) oversight,) * Coordinate and support regulatory submissions and ...

ICON

Senior Clinical Trial Manager

As a Senior Clinical Trial Manager at ICON, you will manage clinical trial operations activities, supporting your team and stakeholders to deliver high-quality outcomes across our clinical programs.

Icon plc

Senior Clinical Trial Manager

Blue Bell, PA · On-site

Local Operations Manager - Advanced - Cross TA ICON is a global healthcare intelligence and ... As a Senior Clinical Trial Manager at ICON, you will manage clinical trial operations activities ...

Icon plc

Senior Clinical Trial Manager

Blue Bell, PA · On-site

Senior Local Operations Manager - Immunology ICON is a global healthcare intelligence and clinical ... As a Senior Clinical Trial Manager at ICON, you will manage clinical trial operations activities ...

TMAC

$65K - $87K/yr

... trial operations, design, site support and scientific engagement with clinical trial sites required General Ophthalmology or Anterior segment ophthalmology therapeutic area experience and/or ...

ICON

Senior Clinical Trial Manager

Blue Bell, PA · On-site +1

Senior Local Operations Manager - Immunology ICON is a global healthcare intelligence and clinical ... As a Senior Clinical Trial Manager at ICON, you will manage clinical trial operations activities ...

Icon plc

Senior Clinical Trial Manager

Blue Bell, PA · On-site

Local Operations Manager - Advanced - Cross TA ICON is a global healthcare intelligence and ... As a Senior Clinical Trial Manager at ICON, you will manage clinical trial operations activities ...

ICON

Senior Clinical Trial Manager

Blue Bell, PA · On-site +1

Local Operations Manager - Advanced - Cross TA ICON is a global healthcare intelligence and ... As a Senior Clinical Trial Manager at ICON, you will manage clinical trial operations activities ...

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Clinical Trial Operations information

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How much do clinical trial operations jobs pay per hour?

As of Jun 15, 2026, the average hourly pay for clinical trial operations in the United States is $39.99, according to ZipRecruiter salary data. Most workers in this role earn between $32.21 and $43.99 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Clinical Trial Operations position, and why are they important?

To thrive in Clinical Trial Operations, you typically need a background in life sciences or healthcare, strong project management abilities, and familiarity with clinical research protocols and regulatory guidelines. Experience with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications like GCP (Good Clinical Practice) are often required. Excellent organizational, communication, and problem-solving skills help you collaborate effectively with cross-functional teams and manage complex study logistics. These competencies are crucial to ensuring clinical trials run smoothly, efficiently, and in compliance with industry standards.

What is a Clinical Trial Operations job?

A Clinical Trial Operations job involves overseeing the planning, execution, and management of clinical trials to ensure they comply with regulatory guidelines and study protocols. Professionals in this role coordinate with investigators, sponsors, and regulatory agencies to ensure trials run smoothly and efficiently. They manage timelines, budgets, patient recruitment, data collection, and compliance with ethical and legal standards. Their ultimate goal is to ensure the trial produces reliable data while prioritizing patient safety.

What are typical daily responsibilities in a Clinical Trial Operations role?

A clinical trial operations professional oversees the planning, implementation, and management of clinical research studies. Daily tasks often include coordinating study timelines, monitoring site performance, ensuring adherence to regulatory requirements, managing study documentation, and communicating with trial sites and sponsors. The role also involves addressing operational issues quickly and adjusting plans as needed to keep the trial on track. This position usually works closely with principal investigators, data managers, regulatory teams, and sponsors, making collaboration and communication essential for success.

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Clinical Trial Operations jobs near you
Infographic showing various Clinical Trial Operations job openings in the United States as of June 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 70% Physical, 6% Hybrid, and 24% Remote job distribution, with an average salary of $83,169 per year, or $40 per hour.
Senior Clinical Trial Associate - Oncology

Senior Clinical Trial Associate - Oncology

Obsidian Therapeutics

Bedford, MA • On-site, Remote

$35.25 - $48/hr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 11 days ago

Job description

About Us
Obsidian Therapeutics is pioneering engineered cell and gene therapies to deliver transformative outcomes for patients. Obsidian's programs apply our cytoDRiVE® technology in Cell and Gene therapy products to control expression of proteins for enhanced therapeutic efficacy and safety. Obsidian's lead program is currently in clinical development for the treatment of patients with metastatic melanoma and non-small cell lung cancer.
We're proud of our diverse talented team and committed to cultivating an environment of inclusion where each person feels a strong sense of belonging and is supported to continuously learn and contribute their best work. Our Research team is based in the heart of Cambridge, MA, and Technical Operations team is based in our purpose built facility in Bedford, MA. Obsidianites enjoy a highly collaborative culture, competitive salary and benefits, and potential for ownership through stock options.
Our Opportunity...
We are looking for a highly motivated Senior Clinical Trial Associate, with a background in oncology clinical trials. As a key contributor within Clinical Operations, you'll help to drive the development of our first clinical stage autologous cell therapy trial targeting solid tumors.
You'll play a key role in driving the operational execution of complex clinical trials, supporting cross-functional coordination, vendor oversight, and ensuring high-quality, inspection-ready study delivery. As a member of our Clinical Operations Team, you will be a vital part of a highly collaborative organization working to achieve Obsidian's vision by translating innovative science into medical breakthroughs for patients starting with our lead program OBX-115, a novel engineered tumor-infiltrating lymphocyte (TIL) therapy.
This is a unique opportunity to be a contributor in a well-funded clinical stage company with blue chip investors, field-leading advisors, best-in-class partners, and an experienced team. You'll help us build a dynamic, innovative, passionate, collaborative, and successful organization focused on delivering transformative therapies in areas of greatest clinical need.
This is a Hybrid role based out of our Bedford, MA location.
You Will...
Core responsibilities
  • Execute and support day-to-day clinical trial operations in alignment with protocols, timelines, and regulatory requirements.
  • Serve as a key point of coordination across internal teams, CROs, and external partners.
  • Maintain and oversee the Trial Master File (TMF), ensuring completeness, accuracy, and audit readiness.
  • Lead TMF quality control activities and proactively address gaps.
  • Support audits and inspections, including preparation and follow-up activities.
  • Coordinate and oversee vendors, including central labs and specialty service providers.
  • Manage biospecimen tracking, logistics, and associated documentation.
  • Monitor vendor performance and escalate issues as needed.
  • Develop, maintain, and improve study tracking tools (e.g., enrollment, sample tracking, timelines).
  • Ensure data accuracy and timely reporting across study activities.
  • Contribute to improvements in clinical operations processes and systems.
  • Drive clear, timely communication across study teams and stakeholders.
  • Plan and facilitate study meetings, including agenda development, minutes, and follow-up actions.
  • Maintain version control and documentation across clinical materials.
  • Support invoice tracking, purchase order coordination, and budget-related activities.

You Bring...
Core Qualifications
  • BS/BA/RN Degree with 6+ years of experience in a life science or a health-related field is preferred.
  • 3+ years working on phase I-IV clinical studies within a biopharmaceutical/biotech, CRO, or academic environment.
  • Experience and understanding of clinical trial operations, preferably in oncology and/or cell therapy space.
  • Solid knowledge of ICH/GCP and regulatory requirements.
  • Excellent planning, coordination, and time management skills
  • Excellent oral, written, and visual communication skills. You listen to understand and communicate effectively and persuasively with partners, colleagues, and leadership.
  • Ability to build and maintain productive relationships at all levels within and across internal teams, and with external partners.
  • Collaborative and accountable - recognizes success requires teamwork and interdisciplinary thinking; shares feedback and ideas to facilitate better outcomes
  • Self-motivated, with a proven ability to meet objectives, timelines, and high standards managing multiple responsibilities in parallel.
  • Flexible - adapts to change in a fast paced, rapidly developing environment
  • Curious and humble - continuous learner, seeks and welcomes input/expertise of others
  • Tenacious and resilient - is not easily overwhelmed by challenges, delivers on commitments, operates with urgency.

Bonus Qualifications
  • Proficiency in Microsoft Project or other project management programs.

Obsidian is committed to equitable and transparent pay practices.
The anticipated base salary range for this role is below. The actual base salary offered will be determined based on a combination of factors, including applicable qualifications, level of education, the depth of experience, unique skills, geographic location, internal equity, and/or business needs. The actual base salary offered will be in accordance with federal, state, and/or local wage requirements for the role's location.
Our competitive compensation package includes an annual incentive bonus as a percentage of actual base salary and long-term incentives in the form of employee stock options, both of which are commensurate with the role's level. We also offer a generous benefits package which includes comprehensive medical, dental, and vision coverage; company contributions to health savings and retirement accounts; ample paid time off; access to wellness programs; and rich career growth opportunities.
Anticipated Base Salary Range
$108,000-$132,000 USD
Obsidian is proud to be an equal opportunity employer, cultivating a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics.

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