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Clinical Trial Operations Jobs (NOW HIRING)

Vanguard Clinical

Clinical Operations Associate (Pool)

CA · Remote

$70K - $80K/yr

We are experts in clinical trial operations with a focus on Clinical Trial Management, CRO/Vendor Oversight, Trial Master File Management, Clinical Monitoring, Quality Assurance, Data Management and ...

Dyne Therapeutics

Senior Clinical Trial Associate

Waltham, MA · On-site

$36.25 - $49.25/hr

The Senior Clinical Trial Associate (CTA) is a key member of the Clinical Operations team responsible for supporting the successful planning, execution, oversight, and closeout of Dyne's global ...

Triwill Group

Clinical Trial Associate

San Francisco, CA · On-site

$94 - $115/hr

Director, Clinical Operations. The Clinical Trial Associate will play a key role in supporting day‑to‑day clinical trial operations across multiple studies. This role is ideal for someone who ...

Intuitive

Clinical Trial Manager

Sunnyvale, CA · On-site

The Clinical Trial Manager (CTM) will manage the day-to-day planning and execution of clinical ... This role is highly operational and execution-focused, partnering closely with clinical sites, CROs ...

Prometrika LLC

Clinical Trial Manager

Cambridge, MA · On-site

$140K - $168K/yr

Manage the operational aspects of clinical trials (e.g., study management, site monitoring and management, trial master file (TMF) oversight,) * Coordinate and support regulatory submissions and ...

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Clinical Trial Operations information

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How much do clinical trial operations jobs pay per hour?

As of Aug 9, 2026, the average hourly pay for clinical trial operations in the United States is $39.99, according to ZipRecruiter salary data. Most workers in this role earn between $32.21 and $43.99 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in clinical trial operations?

To thrive in Clinical Trial Operations, you typically need a background in life sciences or healthcare, strong project management abilities, and familiarity with clinical research protocols and regulatory guidelines. Experience with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications like GCP (Good Clinical Practice) are often required. Excellent organizational, communication, and problem-solving skills help you collaborate effectively with cross-functional teams and manage complex study logistics. These competencies are crucial to ensuring clinical trials run smoothly, efficiently, and in compliance with industry standards.

What is a clinical trial operations?

A Clinical Trial Operations job involves overseeing the planning, execution, and management of clinical trials to ensure they comply with regulatory guidelines and study protocols. Professionals in this role coordinate with investigators, sponsors, and regulatory agencies to ensure trials run smoothly and efficiently. They manage timelines, budgets, patient recruitment, data collection, and compliance with ethical and legal standards. Their ultimate goal is to ensure the trial produces reliable data while prioritizing patient safety.

What are the typical daily responsibilities in clinical trial operations?

A clinical trial operations professional oversees the planning, implementation, and management of clinical research studies. Daily tasks often include coordinating study timelines, monitoring site performance, ensuring adherence to regulatory requirements, managing study documentation, and communicating with trial sites and sponsors. The role also involves addressing operational issues quickly and adjusting plans as needed to keep the trial on track. This position usually works closely with principal investigators, data managers, regulatory teams, and sponsors, making collaboration and communication essential for success.

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Clinical Trial Operations jobs near you
Infographic showing various Clinical Trial Operations job openings in the United States as of August 2026, with employment types broken down into 85% Full Time, 12% Part Time, 1% Temporary, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $83,169 per year, or $40 per hour.

Senior Clinical Trial Associate (CONTRACT)

Entrada Therapeutics

Boston, MA • Remote

$36.50 - $49.75/hr

Contractor

Re-posted 5 days ago

Job description

The Perfect Addition to Our Team

You are patient focused and excited about the opportunity to help support and develop the Clinical Operations organization at Entrada. You enjoy a fast-paced environment and juggling competing priorities. You follow up and follow through, connecting problems with solutions efficiently. You work successfully in a team environment with strong interpersonal skills to effectively build working relationships inside and outside the company. 

The Opportunity

This individual will assist the clinical operations team in the day-to-day operations, study start up and set-up, execution, and closeout of assigned trials.  The individual is accountable to the clinical trial team for the support of trial execution and works collaboratively with cross-functional team members and vendors to ensure proper set-up of trial processes and plans to execute the protocol in accordance with established SOPs and standards.

Responsibilities
  • Support the day-to-day operations of assigned trials to ensure completion per established project team goals and objectives in compliance with ICH/GCP guidelines, from study start-up to close-out.
  • Provides accurate and up-to date clinical trial information within relevant tracking tools and provides regular updates of trial progression to the clinical trial team, including those related to protocol deviations, adverse events, and site personnel trainings.
  • Contribute to the development of trial related plans and manuals.
  • Ensures timely maintenance of the TMF, filing and reconciliation according to regulatory guidance and internal SOPs.
  • Participates and ensures appropriate documentation of clinical team meetings, including meeting minutes, agendas, and action items.
  • Manage vendor POs and trial payments (including budget reconciliation), including invoice review and approval.
  • Support the set-up and management of clinical trial supplies and biosample management where needed (drug product, ancillary and other).
  • Assist in external training activities (suppliers, clinical sites etc.).
  • Assist in the management of trial completion activities, including data review, database lock and trial closeout.
The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

  • Humanity - We genuinely care about patients and about one another.
  • Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
  • Creativity - We are creative problem solvers.
  • Collaboration - We are more than the sum of our parts.
  • Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

  • BA/BS degree with at least 2+ years of relevant experience in clinical operations working at a biotech or pharmaceutical company.
  • Strong understanding of clinical trial operations, including all phases from study start-up to close-out.
  • Ability to work independently and take initiative on projects under minimal supervision.
  • General working knowledge of drug development and ICH/GCP guidelines is required.
  • Previous CRO or vendor management experience preferred.
  • Excellent interpersonal, written, administrative, and computer skills.
  • Excellent verbal and written communication skills with a strong attention for detail.
  • Ability to travel approximately 5% of the time, as determined by the needs of the business. #LI-Remote #LI-JF1
  • This role is a long-term contract position that follows a remote working model, requiring monthly or quarterly travel to the Entrada Therapeutics Headquarters in Boston, MA.

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