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Clinical Trial Operations Manager Jobs (NOW HIRING)

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Senior Clinical Trial Manager

Blue Bell, PA

Senior Local Operations Manager - Immunology ICON is a global healthcare intelligence and clinical ... As a Senior Clinical Trial Manager at ICON, you will manage clinical trial operations activities ...

Immatics NV

Clinical Trial Manager

$130K - $150K/yr

S. Clinical Operations team. The CTM will oversee site management, monitoring oversight, and clinical trial operations activities to ensure compliance with GCP, regulatory requirements, and company ...

Recursion

Senior Clinical Trial Manager

New York, NY · Remote

$136K - $192K/yr

Support the Clinical Project Manager in the execution of trial operations across diverse therapeutic areas to deliver transformative, new medicines to patients * Manage and track clinical trial ...

Pramand

Clinical Trial Manager

Bedford, MA · On-site

The Contract Clinical Trial Manager (CTM) will serve as the sponsor-side operational study lead, responsible for day-to-day execution and oversight of clinical trial activities during study start-up ...

Pramand LLC

Clinical Trial Manager

Bedford, MA · On-site

The Contract Clinical Trial Manager (CTM) will serve as the sponsor-side operational study lead, responsible for day-to-day execution and oversight of clinical trial activities during study start-up ...

Legend Biotech USA, Inc.

... Clinical ... Trial Operational Technologies, Vendor Alliance Management, Site Contracts & Payments, and Sample ...

Pramand

Clinical Trial Manager

Bedford, MA · On-site

$85 - $110/hr

The Contract Clinical Trial Manager (CTM) will serve as the sponsor-side operational study lead, responsible for day-to-day execution and oversight of clinical trial activities during study start-up ...

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Clinical Trial Operations Manager information

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How much do clinical trial operations manager jobs pay per hour?

As of Jun 11, 2026, the average hourly pay for clinical trial operations manager in the United States is $62.52, according to ZipRecruiter salary data. Most workers in this role earn between $50.72 and $70.43 per hour, depending on experience, location, and employer.

What are some common challenges faced by Clinical Trial Operations Managers, and how can they be addressed?

Clinical Trial Operations Managers often encounter challenges such as ensuring regulatory compliance across multiple sites, managing tight timelines, and coordinating diverse teams. Effective communication and proactive planning are essential to address these difficulties. Leveraging project management tools and fostering strong relationships with investigators and site staff can also help streamline operations and reduce risks of delays or protocol deviations.

What is the difference between Clinical Trial Operations Manager vs Clinical Research Coordinator?

AspectClinical Trial Operations ManagerClinical Research Coordinator
CredentialsBachelor's degree; often advanced degrees or certifications in clinical research or managementBachelor's degree in health sciences or related field; certifications like CCRP are common
Work EnvironmentOversees multiple trials, manages teams, and coordinates with stakeholders in clinical settingsWorks directly with participants, manages trial documentation, and supports daily trial activities
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsHospitals, clinics, research institutions

The Clinical Trial Operations Manager focuses on overseeing entire clinical trial processes, managing teams, and ensuring compliance across multiple studies. In contrast, the Clinical Research Coordinator handles the day-to-day activities at the trial site, working closely with participants and supporting trial documentation. Both roles require relevant certifications and are essential in the clinical research industry, but they differ in scope and responsibilities.

What are the key skills and qualifications needed to thrive as a Clinical Trial Operations Manager, and why are they important?

To thrive as a Clinical Trial Operations Manager, you need a strong background in clinical research, regulatory compliance, project management, and a relevant degree such as in life sciences or healthcare. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) guidelines, and certifications like ACRP or SOCRA are highly valued. Leadership, attention to detail, and effective communication are essential soft skills for coordinating teams and stakeholders. These competencies ensure clinical trials are conducted efficiently, ethically, and in accordance with regulatory requirements.

What does a Clinical Trial Operations Manager do?

A Clinical Trial Operations Manager oversees the planning, execution, and completion of clinical trials to ensure they are conducted efficiently, ethically, and in compliance with regulatory standards. They coordinate with cross-functional teams, manage budgets and timelines, and handle any issues that arise during the trial process. This role is crucial for ensuring that new drugs or medical devices are tested safely and effectively before reaching the market.
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What are the most commonly searched types of Clinical Trial Operations jobs? The most popular types of Clinical Trial Operations jobs are:
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Clinical Trial Operations Manager jobs near you
Infographic showing various Clinical Trial Operations Manager job openings in the United States as of June 2026, with employment types broken down into 2% As Needed, 86% Full Time, 11% Part Time, and 1% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $130,034 per year, or $62.5 per hour.
Senior Clinical Trial Manager

Senior Clinical Trial Manager

Icon plc

Blue Bell, PA

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 26 days ago

Job description

Senior Local Operations Manager - Immunology

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


As a Senior Clinical Trial Manager at ICON, you will manage clinical trial operations activities, supporting your team and stakeholders to deliver high-quality outcomes across our clinical programmes.

What You Will Do:

Your focus will be on coordinating clinical trial management delivery, resolving issues, and developing team capability.
Key responsibilities include:

  • Budget Oversight Oversee the clinical portion of the budget to ensure efficient resource allocation.
  • Ensuring Effective Study Oversight: Develop monitoring plans and tools, ensuring effective study oversight.
  • Optimizing Performance: Train and mentor Clinical Research Associates (CRAs) to optimize their performance.
  • Timely Study Start-Up & Enrollment: Drive enrollment and lead study start-up activities, adhering to timelines.
  • Improving Study Integrity Review trip reports and implement corrective and preventative action plans when necessary.Building Productive Relationships: Foster productive relationships with Sponsors, vendors, and cross-functional teams.

Your Profile:

You will have solid clinical trial management experience, with the ability to manage competing priorities and develop your team.
Required qualifications and experience:

  • A minimum of 4+ years of experience in a Clinical Trial Management position at a CRO or Pharmaceutical Organization.
  • Bachelor's degree in health, life sciences, or other relevant fields of study.
  • At least 10+ years of relevant experience in clinical trial management.
  • Preferred: 2+ years of monitoring experience.
  • Experience in managing complex or global trials is advantageous.
  • Preferred: Experience in managing all trial components from start-up to database lock.
  • Preferred: Experience in coaching/mentoring other CTMs, leading a team of CTMs, and participating in departmental initiatives.
  • Willingness to travel as required (approximately 25%)

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a requesthere.

Are you a current ICON Employee? Please click here to apply

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