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Clinical Trial Operations Manager Jobs (NOW HIRING)

ICON

Clinical Trial Manager

As a Clinical Trial Manager at ICON, you will manage clinical trial operations activities, supporting your team and stakeholders to deliver high-quality outcomes across our clinical programs. What ...

Immatics NV

Clinical Trial Manager

Houston, TX

$130K - $150K/yr

S. Clinical Operations team. The CTM will oversee site management, monitoring oversight, and clinical trial operations activities to ensure compliance with GCP, regulatory requirements, and company ...

Immatics NV

Clinical Trial Manager

Houston, TX

$130K - $150K/yr

S. Clinical Operations team. The CTM will oversee site management, monitoring oversight, and clinical trial operations activities to ensure compliance with GCP, regulatory requirements, and company ...

WEP Clinical

Clinical Trial Project Manager

Provide day-to-day accountability for the operational delivery of assigned clinical trials ... Client & Stakeholder Management * Act as the primary client contact for clinical trial operations ...

Immatics NV

Clinical Trial Manager

Houston, TX · On-site

$130K - $150K/yr

S. Clinical Operations team. The CTM will oversee site management, monitoring oversight, and clinical trial operations activities to ensure compliance with GCP, regulatory requirements, and company ...

Immatics NV

Clinical Trial Manager

Houston, TX · On-site

$130K - $150K/yr

S. Clinical Operations team. The CTM will oversee site management, monitoring oversight, and clinical trial operations activities to ensure compliance with GCP, regulatory requirements, and company ...

Kardigan

Clinical Trial Manager

Princeton, NJ · On-site

As a Clinical Trial Manager (CTM), you will be part of the Clinical Operations team reporting to the asset's Clinical Trial or Clinical Program Lead. This position will be responsible for the ...

SAB

Clinical Sample Manager

Sioux Falls, SD · Remote

$130K - $150K/yr

Provide operational oversight of assigned clinical trial service providers, ensuring services are ... Oversee sample management activities, including site supply management, kit ordering, sample ...

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How much do clinical trial operations manager jobs pay per hour?

As of Jul 24, 2026, the average hourly pay for clinical trial operations manager in the United States is $62.52, according to ZipRecruiter salary data. Most workers in this role earn between $50.72 and $70.43 per hour, depending on experience, location, and employer.

What are some common challenges faced by Clinical Trial Operations Managers, and how can they be addressed?

Clinical Trial Operations Managers often encounter challenges such as ensuring regulatory compliance across multiple sites, managing tight timelines, and coordinating diverse teams. Effective communication and proactive planning are essential to address these difficulties. Leveraging project management tools and fostering strong relationships with investigators and site staff can also help streamline operations and reduce risks of delays or protocol deviations.

What is the difference between Clinical Trial Operations Manager vs Clinical Research Coordinator?

AspectClinical Trial Operations ManagerClinical Research Coordinator
CredentialsBachelor's degree; often advanced degrees or certifications in clinical research or managementBachelor's degree in health sciences or related field; certifications like CCRP are common
Work EnvironmentOversees multiple trials, manages teams, and coordinates with stakeholders in clinical settingsWorks directly with participants, manages trial documentation, and supports daily trial activities
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsHospitals, clinics, research institutions

The Clinical Trial Operations Manager focuses on overseeing entire clinical trial processes, managing teams, and ensuring compliance across multiple studies. In contrast, the Clinical Research Coordinator handles the day-to-day activities at the trial site, working closely with participants and supporting trial documentation. Both roles require relevant certifications and are essential in the clinical research industry, but they differ in scope and responsibilities.

What are the key skills and qualifications needed to thrive as a Clinical Trial Operations Manager, and why are they important?

To thrive as a Clinical Trial Operations Manager, you need a strong background in clinical research, regulatory compliance, project management, and a relevant degree such as in life sciences or healthcare. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) guidelines, and certifications like ACRP or SOCRA are highly valued. Leadership, attention to detail, and effective communication are essential soft skills for coordinating teams and stakeholders. These competencies ensure clinical trials are conducted efficiently, ethically, and in accordance with regulatory requirements.

What does a Clinical Trial Operations Manager do?

A Clinical Trial Operations Manager oversees the planning, execution, and completion of clinical trials to ensure they are conducted efficiently, ethically, and in compliance with regulatory standards. They coordinate with cross-functional teams, manage budgets and timelines, and handle any issues that arise during the trial process. This role is crucial for ensuring that new drugs or medical devices are tested safely and effectively before reaching the market.
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Clinical Trial Operations Manager jobs near you
Infographic showing various Clinical Trial Operations Manager job openings in the United States as of July 2026, with employment types broken down into 2% As Needed, 73% Full Time, 17% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $130,034 per year, or $62.5 per hour.

Sr. Manager, Clinical Trial Operations Planning & Analytics

Legend Biotech US

Somerset, NJ • Hybrid

Other

Posted 22 hours ago

Job description

Legend Biotech is seeking a Sr. Manager, Clinical Trial Operations Planning & Analytics as part of the Clinical Operations team based in Somerset, NJ.

Role Overview

The Sr. Manager, Clinical Trial Operations Planning & Analytics is responsible for the strategic planning and analytics capability to support current and future Legend pipeline studies. This role will establish scalable approaches for feasibility, site identification, study startup planning, forecasting, and trial performance analytics to improve predictability and enable earlier operational intervention. The position partners closely with Clinical Operations leadership and cross-functional stakeholders to determine and assess assumptions, refine strategy, and translate data into actionable operational decisions across the study lifecycle.

Key Responsibilities

  • Lead development of standardized frameworks, tools, and processes for feasibility, site identification, enrollment forecasting, study startup planning, and predictive trial performance modeling across pipeline studies.
  • Develop data-driven approaches to identify the right countries and sites globally to support activation and enrollment acceleration and to predict key operational outcomes such as startup timing, enrollment, and study completion.
  • Build scenario models and planning outputs to support base and best case operational strategies and contingency planning.
  • Establish contingency planning triggers, risk indicators, and escalation thresholds based on modeled performance risk.
  • Partner with study teams, CROs, and cross-functional stakeholders to pressure-test trial assumptions and refine country and site strategies.
  • Create and maintain dashboards and analytics to monitor startup, activation, enrollment, and delivery risk trends.
  • Translate study and portfolio performance data into actionable insights and executive-ready recommendations for senior leadership.
  • Support continuous refresh of assumptions as study conditions, portfolio priorities, and external dynamics evolve.
  • Capture lessons learned and convert them into reusable planning tools, templates, and methodologies that improve cross-study consistency.
  • Represent the function in internal planning discussions and external partner interactions related to feasibility, forecasting, and performance analytics.
  • Performs other duties as required.
  • Works closely with the Sr. Director and VP of Clinical Operations. Clinical Operations Capabilities & Scalability and collaborates with Clinical Operations study teams, Clinical Development, IT, ITQA Biostatistics, Regulatory, Project Management, Procurement, Finance, QA, and CRO/vendor.

Requirements

  • Minimum degree requirements of a bachelor's degree (BA, BS) in scientific, health care, data, or related discipline. Advanced degree preferred.
  • 7+ years of pharmaceutical, biotech, CRO, or related clinical research experience; 10+ years preferred.
  • Experience working with data sources to inform trial forecast modeling
  • Experience in clinical operations planning, feasibility, study startup, operational analytics, or related functions required.
  • Experience supporting global site identification, country strategy, or enrollment planning strongly preferred.
  • Experience building dashboards, models, or analytics to support clinical trial execution preferred.
  • Oncology, cell therapy, or early-phase clinical development experience preferred.
  • Ability to travel as necessary (approximately 10%).
  • Knowledge/familiarity with tools to enable trial forecasting and modeling.
  • Strong critical thinking, analytical, strategic planning, and problem-solving skills.
  • Effective oral, written, and interpersonal communication skills with strong presentation capability.
  • Forward and critical thinker with ability to translate data into decisions.
  • Strong organizational and project management skills and the ability to multitask.
  • Computer literacy required (MS Word, MS Excel, MS PowerPoint, MS Project, and analytics/visualization tools).
  • Working knowledge of GCP, FDA, and ICH Guidelines.

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