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Clinical Research Informatics Jobs in California

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Clinical Research Informatics information

See California salary details

$51.3K

$102.2K

$161.9K

How much do clinical research informatics jobs pay per year?

As of Aug 27, 2026, the average yearly pay for clinical research informatics in California is $102,240.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,000.00 and $114,000.00 per year, depending on experience, location, and employer.

What is clinical research informatics?

A Clinical Research Informatics job involves managing and analyzing healthcare data to support clinical research and improve patient outcomes. Professionals in this field develop and maintain databases, ensure data integrity, and utilize informatics tools to streamline clinical trials. They collaborate with researchers, clinicians, and IT specialists to optimize data collection, integration, and analysis. This role requires knowledge of biomedical research, data science, and regulatory compliance.

What does a clinical research informatics specialist do?

Professionals in Clinical Research Informatics are usually responsible for designing and managing databases for clinical studies, ensuring data integrity, and analyzing research data to support scientific findings. They often coordinate with clinical researchers, IT specialists, and regulatory teams to develop data collection protocols and maintain compliance with industry standards. Regular tasks may include troubleshooting data issues, preparing reports, and training staff on informatics systems. This role often involves both independent work and close collaboration with multidisciplinary teams, offering a dynamic and impactful work environment.

What are the key skills and qualifications needed to thrive in clinical research informatics?

Excelling in Clinical Research Informatics requires a solid background in clinical research methodologies, health informatics, data management, and often a relevant degree such as in biomedical informatics or computer science. Proficiency with data analysis tools (like SAS, R, or Python), electronic data capture systems (such as REDCap), and knowledge of healthcare regulatory standards (HIPAA, GCP) are typically expected. Strong communication, analytical thinking, and the ability to collaborate across multidisciplinary teams are important soft skills. These competencies ensure effective collection, management, and interpretation of clinical data, supporting high-quality research outcomes and regulatory compliance.

What are the most commonly searched types of Clinical Research Informatics jobs in California?

The most popular types of Clinical Research Informatics jobs in California are:

Infographic showing various Clinical Research Informatics job openings in California as of August 2026, with employment types broken down into 3% As Needed, 76% Full Time, 14% Part Time, and 7% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $102,240 per year, or $49.2 per hour.

Assistant/Associate Specialist For the Department of Public Health Sciences-Informatics Division

University of California

Sacramento, CA • On-site

$70 - $110/hr

Other

Posted 4 days ago


University Of California rating

8.5

Company rating: 8.5 out of 10

Based on 34 frontline employees who took The Breakroom Quiz

82nd of 623 rated colleges and universities


Job description

NATURE AND PURPOSE

The Department of Public Health Sciences at the University of California Davis, School of Medicine is recruiting for a full- or part-time Specialist at the Assistant/Associate rank in Health Informatics.

The position of Specialist has a narrow focus in a specialized area and provides technical expertise in the planning and execution of research projects involving artificial intelligence (AI), natural language processing (NLP), and clinical research informatics. The Specialist applies professional knowledge to support research activities, maintains technical competence in designated areas of specialization, and stays informed of emerging developments in AI-enabled clinical research. Under the direction of the Principal Investigator (PI), the Specialist collaborates with faculty, staff, and research partners to advance research objectives and contributes to the development of research methods, datasets, analyses, and scholarly products.

Normally, Specialists do not have Principal Investigator (PI) status but may obtain permission by exception and/or collaborate with a PI in preparing research proposals for extramural funding. The Specialist is evaluated for merit and promotion using three basic criteria outlined below.

The incumbent will work under the supervision of Dr. Anderson and be able to work cooperatively and collegially in a diverse environment.

I. RESEARCH (90% EFFORT) A. AI and Pilot Data Research Support
  • Apply knowledge of generative AI, NLP, and related technologies to support research initiatives.
  • Develop and maintain pilot datasets and research materials used for workflow development, model evaluation, and training activities.
  • Organize, validate, and document research datasets, including data provenance and quality assurance procedures.
  • Collaborate with research staff and project stakeholders to identify project requirements and implement research workflows.
B. Clinical Research Informatics Support
  • Analyze and document user requirements, workflows, and functional specifications for AI-enabled clinical research projects.
  • Coordinate with clinical and research stakeholders to gather and synthesize project information.
  • Prepare technical documentation, reports, and summaries supporting research objectives and system implementation.
  • Identify opportunities to integrate AI technologies with existing clinical research systems and informatics infrastructure.
C. Model Evaluation and Dataset Development
  • Develop, curate, and maintain datasets supporting AI model development and evaluation.
  • Perform annotation, labeling, quality control, and curation activities for NLP and machine learning research.
  • Conduct evaluations of language models and related AI technologies using established research methodologies.
  • Analyze evaluation results and prepare summaries of research findings.
  • Contribute to manuscripts, abstracts, presentations, posters, technical reports, and other scholarly products.
  • Build and maintain evaluation frameworks and benchmarks to assess model performance, reliability, consistency, and safety in clinical research workflows.
  • Document AI methods, data provenance, architectural limitations, and evaluation results to ensure reproducibility and appropriate use.
  • Support weekly laboratory meetings and journal clubs through presentation of technical findings and evaluations.
  • Participate actively in research meetings, journal clubs, and collaborative scientific discussions.
D. AI Technology Assessment
  • Evaluate emerging AI models, platforms, and technologies for applicability to ongoing research projects.
  • Design and conduct comparative assessments of prompting strategies, retrieval methods, and model configurations under the direction of the PI.
  • Maintain detailed documentation of experimental procedures, model performance, and research outcomes.
  • Prepare comparative analyses and recommendations regarding research technologies and methodologies.
  • Evaluate LLM architectures, agentic frameworks, APIs, retrieval-augmented generation (RAG) approaches, and prompt engineering strategies for clinical research applications.
  • Compare candidate models across accuracy, latency, cost, privacy, and regulatory considerations.
E. Literature Review and Research Support
  • Conduct comprehensive literature reviews related to artificial intelligence, natural language processing, health informatics, and clinical research.
  • Critically evaluate and summarize findings from peer-reviewed publications and technical reports.
  • Maintain organized reference libraries and documentation of relevant software tools and research resources.
  • Present literature reviews, technical updates, and research progress to project investigators and collaborators/
  • Maintain a curated knowledge base of emerging AI methods, benchmarks, software tools, and regulatory guidance relevant to health AI.
II. PROFESSIONAL COMPETENCE AND ACTIVITY (8% EFFORT)
  • Maintain current knowledge of developments in AI, NLP, clinical research informatics, and related fields.
  • Complete and maintain required certifications and compliance training, including Human Subjects Research, Good Clinical Practice (GCP), Responsible Conduct of Research, and University cybersecurity requirements.
  • Participate in regular meetings with the PI and research team to discuss research progress, technical challenges, and project priorities.
  • Pursue professional development activities that enhance technical and research competencies relevant to project objectives.
III. UNIVERSITY AND PUBLIC SERVICE (2% EFFORT)
  • Participate in departmental, school, and university service activities, as appropriate.
  • Provide guidance and technical assistance to undergraduate student assistants, interns, and other research personnel.
  • Contribute to collaborative, interdisciplinary, and team-based research initiatives within the program.

This recruitment is conducted at the assistant/associate rank. The resulting hire will be at the assistant/associate rank, regardless of the proposed appointee's qualifications.

A bachelor’s degree plus three or more years of research experience or a master’s degree in Informatics or a relevant field.

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