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Clinical Operations Manager Jobs in Houston, TX (NOW HIRING)

ARTIDIS

Business Operations Manager

Houston, TX · On-site

ARTIDIS is a clinical-stage health-tech start-up founded in Basel, Switzerland that has developed ... Job Purpose The Business Operations Manager (US Region) is responsible for contributing to the ...

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Clinical Operations Manager information

See Houston, TX salary details

$33.4K

$93.6K

$178.1K

How much do clinical operations manager jobs pay per year?

As of Aug 23, 2026, the average yearly pay for clinical operations manager in Houston, TX is $93,624.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,200.00 and $108,400.00 per year, depending on experience, location, and employer.

What is a clinical operations manager?

Clinical Operations Managers are professionals responsible for overseeing the day-to-day administrative and operational functions of clinical trials or healthcare facilities. They ensure that clinical protocols are followed, resources are efficiently allocated, and regulatory compliance is maintained. These managers coordinate between healthcare staff, researchers, and external partners to facilitate smooth clinical operations and high-quality patient care. Their role is essential in ensuring that clinical services or trials are delivered effectively, safely, and on schedule.

What does a clinical operations manager do?

A clinical operations manager or director is a health care professional who oversees the operations of a medical facility. Their duties include meeting regularly with department heads, reading assessments of employee productivity, and managing administrative tasks, such as budgeting and billing. Qualifications for a clinical operations manager include experience in medical administration, management skills, and organizational skills. An advanced degree in public health or health administration can significantly improve your job opportunities.

What are the key skills and qualifications needed to thrive as a clinical operations manager, and why are they important?

To thrive as a Clinical Operations Manager, you need expertise in clinical trial management, regulatory compliance, and healthcare operations, usually supported by a degree in a health-related field and relevant experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as ACRP or SOCRA are commonly required. Strong leadership, problem-solving abilities, and effective communication are essential soft skills for this role. These skills ensure efficient trial execution, regulatory adherence, and successful coordination across teams and stakeholders.

What are the main challenges clinical operations managers face when overseeing multiple clinical trials simultaneously?

Clinical Operations Managers often juggle several clinical trials at once, which can present challenges such as maintaining consistent quality across studies, ensuring timely patient recruitment, and managing diverse teams. They must coordinate with cross-functional departments, address regulatory compliance, and troubleshoot unforeseen issues, all while staying on schedule and within budget. Effective organizational skills, proactive communication, and adaptability are essential for overcoming these challenges and ensuring successful trial outcomes.

What is the difference between Clinical Operations Manager vs Clinical Research Coordinator?

AspectClinical Operations ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, management experienceBachelor's degree in health or life sciences, research training
Work EnvironmentOversees multiple clinical trials, manages teamsAssists with daily trial activities, data collection
Employer & IndustryPharmaceutical companies, CROs, hospitalsResearch institutions, hospitals, clinical sites

The Clinical Operations Manager focuses on overseeing entire clinical trial operations, managing teams, and ensuring compliance. In contrast, the Clinical Research Coordinator handles the day-to-day activities at trial sites, such as patient recruitment and data collection. Both roles require related credentials and work within the clinical research industry, but their responsibilities and scope differ significantly.

More about Clinical Operations Manager jobs

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The most popular types of Clinical Operations jobs in Houston, TX are:

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For Clinical Operations Manager jobs in Houston, TX, the most frequently searched job titles are:

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Cities near Houston, TX with the most Clinical Operations Manager job openings:

Clinical Operations Manager jobs near you
Infographic showing various Clinical Operations Manager job openings in Houston, TX as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 12% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $93,624 per year, or $45 per hour.

Clinical Operations Manager

ALLIANCE CLINICAL LLC

Houston, TX • On-site

$90K - $120K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted yesterday

Job description

About the Role:

The Clinical Operations Manager is responsible for daily clinic operations, administrative functions, and the management of office personnel. This role acts as a liaison between patients, medical staff, clinic staff, and management to ensure optimal clinic functioning. Additionally, the Manager plays an essential role in ensuring policies and procedures are followed, interpreting and communicating regulatory and protocol requirements, and ensuring that the clinic delivers exceptional patient care and functions efficiently.

Duties and Responsibilities:

  • Manage and train clinic site personnel.
  • Identify and implement strategies to expand the research capabilities at the site in alignment with the overall site business plan.
  • Oversee the implementation and maintenance of ACN quality standards at the site, including reading, analyzing, and interpreting regulations, protocols, and procedures to ensure studies are conducted in accordance with ICH GCPs.
  • Manage site budgets and expenses, including the analysis of figures, study costs, and other financial and operational data.
  • Work with the Medical Director/PI to address any study and/or clinical quality-related matters.
  • Ensure timely and appropriate communication with Sponsors and IRBs as necessary.
  • Develop site staffing plans to ensure the successful and efficient conduct of research studies. Identify and fulfill any site resource needs that are necessary to successfully conduct and/or recruit research studies.
  • Oversee the development of the patient recruitment plan and patient outreach process. Make ongoing adjustments/modifications to recruitment strategies based on the timely review of results to ensure financial and study-specific targets. Closely collaborate with any external vendors to facilitate successful patient enrollment strategies.
  • Read, comprehend, and communicate study protocols.
  • Oversee SIV, PSDV, and IMV.
  • Manage and facilitate study startup documentation, training, supplies, and timelines of study protocols.
  • Develop and implement operational plans, timelines, and budgets for clinical trials.
  • Share best practices with other ACN site locations with the goal of raising the overall level of operational competencies at ACN.
  • Monitor study progress, resolve data issues, and prepare status reports for leadership.
  • Work closely with CROs, CRAs, and IRBs.
  • Maintain site regulatory files.
  • Document temperatures for IP stored on-site.
  • Audit study e-source documentation to comply with study protocols.
  • Support audits and inspections.
  • Monitor study metrics and key performance indicators (KPIs).
  • Perform other duties as assigned.

Qualifications:

  • Bachelor’s degree preferred in healthcare or equivalent clinical research experience.
  • Minimum of 5 years of clinical management experience or equivalent applicable experience in the clinical research industry.
  • Minimum of 3 years of experience working as a Clinical Research Coordinator required.
  • Comprehensive knowledge of FDA, GCP, and confidentiality.
  • Proven success in managing teams and working in direct patient care required.
  • Proficient problem-solving skills and conflict resolution.
  • Proficient in Microsoft Word, Excel, and PDF.
  • Excellent verbal and written communication skills.
  • A proven ability to constantly prioritize multiple projects in a rapidly changing environment.
  • Must be comfortable with a rapid-growth company.
  • Monitor project timelines and ensure milestones are met.

ACN does not provide visa sponsorship for this role. Candidates who will require immigration or visa sponsorship at any time now or in the future (including, but not limited to, H‑1B, TN, or STEM OPT training plans) are not eligible for this role.

Certificates, Licenses, and Registrations:

  • CPR certification.
  • Certified as a Medical Assistant or in Phlebotomy.
  • IATA and GCP certifications.

Benefits: Medical, Dental, Vision, 401k, PTO and more!

Location: Monday – Friday / on-site / Houston, TX

About the Company:

At Alliance Clinical Network, our mission is to advance medical research by enrolling diverse populations in high-quality clinical trials. We are committed to maintaining the highest standards of integrity and excellence, and to ensuring that every participant receives respectful and compassionate care. We strive to build a tightly knit, supportive and collaborative environment where our team members can thrive and make meaningful contributions to human health.