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Clinical Operation Manager Jobs in Riverside, CA

Tarsus Pharmaceuticals

Sr Director, Clinical Sciences

Irvine, CA · On-site +1

$85K - $117K/yr

... management. This role partners closely with Clinical Operations, Regulatory, Biostats, Medical Affairs, and Commercial to translate target product profiles into robust clinical development plans and ...

Titan Placement Group

Clinical Director

Orange, CA · On-site

$145K/yr

... • Manage an interdisciplinary team including therapists, Psychiatrists, dietitians, health coaches, and support staff • Opportunity to build programs, culture, and clinical operations • ...

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All JobsClinical Operation JobsClinical Operation Manager JobsClinical Operation Manager Jobs in Riverside, CA

Clinical Operation Manager information

See Riverside, CA salary details

$36.5K

$102.3K

$194.6K

How much do clinical operation manager jobs pay per year?

As of Sep 3, 2026, the average yearly pay for clinical operation manager in Riverside, CA is $102,281.00, according to ZipRecruiter salary data. Most workers in this role earn between $75,600.00 and $118,400.00 per year, depending on experience, location, and employer.

What is a clinical operation manager?

Clinical Operation Managers are professionals responsible for overseeing the daily operations of clinical research sites, medical facilities, or departments. They ensure that clinical trials or healthcare services are conducted efficiently, comply with regulations, and meet quality standards. Their duties often include supervising staff, managing budgets, implementing policies, and coordinating between various teams. Clinical Operation Managers play a crucial role in ensuring that patient care and research activities run smoothly and effectively.

What are the key skills and qualifications needed to thrive as a clinical operation manager?

To thrive as a Clinical Operation Manager, you need expertise in clinical project management, regulatory compliance, and a background in healthcare or life sciences, often supported by a relevant degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications such as PMP or Six Sigma are commonly required. Strong leadership, problem-solving abilities, and excellent communication skills set top performers apart in this role. These competencies are essential for ensuring efficient clinical operations, maintaining regulatory standards, and leading teams to deliver successful trial outcomes.

What are some common challenges clinical operation managers face when coordinating multi-site clinical trials?

Clinical Operation Managers often encounter challenges such as ensuring consistent protocol adherence across all sites, managing communication among geographically dispersed teams, and maintaining timelines despite unexpected delays. They must also address regulatory differences between sites and troubleshoot issues related to patient recruitment and data collection. Success in this role requires strong organizational skills, adaptability, and effective collaboration with investigators, coordinators, and regulatory personnel.

What is the difference between Clinical Operation Manager vs Clinical Research Coordinator?

AspectClinical Operation ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, life sciences, or related field; often with project management certificationsBachelor's degree in health sciences, nursing, or related field; often with research-specific training
Work EnvironmentOversees multiple clinical trials, manages teams, and ensures compliance at a departmental levelCoordinates daily activities of clinical trials, interacts directly with participants and investigators
Employer & IndustryPharmaceutical companies, biotech firms, hospitals, research institutionsResearch sites, hospitals, academic institutions, contract research organizations

The Clinical Operation Manager focuses on overseeing clinical trial operations, managing teams, and ensuring compliance across projects. In contrast, the Clinical Research Coordinator handles the day-to-day activities of specific trials, working closely with participants and investigators. Both roles require relevant healthcare or science credentials, but their scope and responsibilities differ significantly.

What job categories do people searching Clinical Operation Manager jobs in Riverside, CA look for?

The top searched job categories for Clinical Operation Manager jobs in Riverside, CA are:

What cities near Riverside, CA are hiring for Clinical Operation Manager jobs?

Cities near Riverside, CA with the most Clinical Operation Manager job openings:

Clinical Operation Manager jobs near you
Infographic showing various Clinical Operation Manager job openings in Riverside, CA as of August 2026, with employment types broken down into 83% Full Time, 15% Part Time, and 2% Contract. Highlights an 79% Physical, 2% Hybrid, and 19% Remote job distribution, with an average salary of $102,281 per year, or $49.2 per hour.

Sr Director, Clinical Sciences

Tarsus Pharmaceuticals

Irvine, CA • On-site

$85K - $117K/yr

Full-time

Medical, Dental, Vision, PTO

Posted 13 days ago

Job description

About the Role
The Sr Director, Clinical Sciences will lead Clinical Science (Eyecare) function, accountable for the scientific integrity, quality, and strategic impact of all eyecare clinical studies from early development through late-stage registration and lifecycle management. This role partners closely with Clinical Operations, Regulatory, Biostats, Medical Affairs, and Commercial to translate target product profiles into robust clinical development plans and high-quality trial designs.
Let's talk about some of the key responsibilities of the role:
  • Provide scientific leadership to cross-functional study and program teams, ensuring timely study start-up, enrollment, database lock, analysis, and readouts.
  • Lead the design of clinical development plans and individual study protocols (objectives, endpoints, inclusion/exclusion, assessments, statistical assumptions)
  • Maintains direct ownership of clinical deliverables, actively contributing to protocol development, document authoring, data review, study-level problem solving and execution decisions to ensure scientific rigor and operational excellence.
  • Shape clinical plans including timelines, budgets and oversight of clinical teams.
  • Build and maintain strong relationships with investigators, KOLs, and external partners; contribute to publication strategy and scientific communications
  • Drive innovation in clinical endpoints, biomarkers, and digital tools, and champion continuous improvement in clinical science processes, templates, and data review frameworks
  • Author and critically review key clinical and regulatory documents, including protocols, SAPs, CSRs, IBs and clinical value dossiers, ensuring scientific rigor, regulatory alignment and quality execution.
  • Conduct research to develop foundational education material to inform the early development program strategies.
  • Interpret clinical data and support data-driven decisions.
  • Serve as program lead on early development Core teams, investigator meetings and scientific advisory boards.
  • Engage with internal and external stakeholders, including KOLs and regulators.
  • Exhibits and fosters key leadership competencies, including an innovative mindset, strong business acumen, an outcome-driven orientation, and a commitment to growing and expanding the capabilities and capacity of the team.
  • Collaborate with Clinical Operations, Regulatory Affairs, Translational Sciences, Biostatistics, Medical Affairs and others to ensure robust trial design, scientific and operational alignment and execution .

Factors for Success:
  • Advanced degree in sciences (e.g. PharmD, MD, PhD) with deep experience in early clinical development
  • Experience in ophthalmology is preferred; dermatology or infectious diseases a plus.
  • Minimum of 10 years of biotech/pharmaceutical clinical development experience, with a minimum of 8 years leadership in clinical trial management experience required
  • Established leadership track record with evidence of excellent performance-based people management experience, problem solving, collaboration, cross functional leadership and effective communication skills.
  • Expertise with SOPs, GCPs and regulatory and compliance guidelines for clinical trials.
  • Must be willing to be "hands on" and delve into details

Leadership Competencies - This role requires mastery of the Tarsus Leadership Competencies for Leading Teams, including:
  • Empowering Others - Fosters empowerment by aligning authority with accountability, developing leaders' decision-making capability, and creating systems that support performance and growth.
  • Emotional Intelligence - Foster trust and psychological safety, navigating complex interpersonal dynamics with compassion and accountability, and adapting leadership style to support others while maintaining composure under pressure.
  • Grows Capacity - Builds organizational capacity by developing talent systems, coaching cultures, and strategic partnerships that grow leadership strength and prepare the next generation of leaders.
  • Business Acumen - Demonstrates strong business acumen by anticipating market dynamics and using financial and strategic insight to guide investments, manage risk, and align priorities with long-term organizational value.
  • Innovative Mindset and Action - Demonstrates an innovative mindset by championing new ideas, investing in enabling systems and partnerships, and translating innovation into sustainable growth and organizational resilience.

Few Other Details Worth Mentioning:
  • The position will be based in our beautiful Irvine office, complete with onsite gym, pool, snacks, drinks, and occasional catered meals. We provide a hybrid work environment. Remote work is an option.
  • We are passionate about our culture! Our Tarsans live our values of commitment to patients, empowerment to champion innovation, and teamwork to amplify impact!
  • This position reports directly to our SVP, Development
  • Some travel may be required - up to 30%

At Tarsus, we understand the importance of attracting and retaining top talent. The expected base pay range for this position is $255,000 - $357,000 plus bonus, stock equity, and comprehensive benefits. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training. Our benefits include health, dental and vision insurance benefits to ensure your well-being. We believe in work-life balance and offer generous paid time off, including vacation, holidays, and personal days. For more details regarding Tarsus benefits, please visit: https://eb.alliant.com/26tarsusbenefitssnapshot.
#LI-Remote
Tarsus Pharmaceuticals, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.

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