Chief Operations Manager Jobs in Wayne, PA (NOW HIRING)

At DuPont, our purpose is to empower the world with essential innovations to thrive. We work on things that matter. Whether it’s providing clean water to more than a billion people on the planet, producing materials that are essential in everyday technology devices from smartphones to electric vehicles, or protecting workers around the world. Discover the many reasons the world’s most talented people are choosing to work at DuPont. Why Join Us | DuPont Careers

Every day, scientists and entrepreneurs at The Innovation Space are working to turn promising discoveries into companies and solutions to change the world for the better with the potential to improve lives, strengthen industries, and address important global challenges.

The Innovation Space is a nonprofit organization and entrepreneurial ecosystem that helps science-based startups transform breakthrough technologies into commercially viable businesses. Located on the historic Experimental Station campus in Wilmington, Delaware, The Innovation Space provides an integrated platform of laboratory and office facilities, shared scientific equipment, entrepreneurial programs, expert mentorship, funding opportunities, and connections to investors and strategic partners.

Established through a public-private partnership among the State of Delaware, DuPont, and the University of Delaware, The Innovation Space supports entrepreneurs working across life sciences, industrial biotechnology, advanced materials, clean technology, renewable energy, nutrition, and related fields. Its collaborative ecosystem brings together scientists, entrepreneurs, business leaders, investors, and service providers to accelerate commercialization, company growth, and real-world impact.

The Innovation Space is a collaborative, mission-driven, and entrepreneurial organization. Our work moves quickly, priorities evolve, and team members regularly contribute beyond traditional functional boundaries. We value curiosity, sound judgment, mutual respect, practical problem-solving, and a shared commitment to helping entrepreneurs succeed.

Since 2017, over 160 companies supported by The Innovation Space have raised more than $1.24 billion in capital. In 2025, The Innovation Space and its portfolio of startups supported approximately 2,490 jobs and generated an estimated $703.9 million in economic output nationwide.

Learn more at www.innovationspace.org.

The Chief Operations Officer leads the laboratory, facilities, scientific support, and business operations that enable The Innovation Space and its client companies to succeed. Reporting operationally to the President & CEO, the COO translates organizational strategy into safe, reliable, and scalable systems across facilities, finance, legal, technology, people operations, EH&S, compliance, and risk management. This highly visible role combines enterprise leadership with hands‑on execution and offers the opportunity to help scientists and entrepreneurs advance breakthrough technologies toward commercial and societal impact.

The COO leads a capable multidisciplinary team with four direct reports: the Client Experience Manager, Assistant Director of Facilities, Senior Scientist and Laboratory Manager, and Laboratory Coordinator. The COO also draws upon specialized expertise from DuPont and an established network of external financial and legal advisors, contractors, and service partners. This combination of internal capability and external support enables the COO to provide enterprise-level leadership, delegate effectively, and remain sufficiently close to day‑to‑day execution to engage directly when needed.

The COO will be a DuPont employee seconded to The Innovation Space. The President & CEO of The Innovation Space will provide day‑to‑day direction, establish organizational priorities, and oversee performance in the role, while DuPont will retain responsibility for employment administration. This is an opportunity to help shape a nationally significant center for science‑based entrepreneurship. The COO will work alongside scientists, founders, investors, corporate leaders, and public‑sector partners advancing new solutions across health, biotechnology, advanced materials, clean technology, energy, and nutrition.

• Provide overall leadership for the organization’s 130,000-square-foot laboratory, office, and collaboration facility, ensuring safe, reliable, and cost-effective delivery of infrastructure, technical capabilities, and services.

• Lead laboratory and facility planning, infrastructure reliability, preventive maintenance, capital planning, and significant construction and improvement projects.

• Manage operating budgets and external contractors, vendors, and service providers supporting laboratory and facility operations.

• Partner with Innovation Space clients to understand their operational and technical needs and continually improve laboratory capabilities, service quality, reliability, utilization, and the overall client experience.

• Oversee budgeting, forecasting, accounting, cash management, financial reporting, audits, tax coordination, and internal financial controls, working closely with the President & CEO and external financial resources.

• Lead annual operating and capital planning and support financial reporting to organizational leadership, the Board of Directors, funding partners, and government agencies.

• Oversee the administrative and financial management of government, foundation, and corporate grants, including budgeting, compliance, allowable-cost requirements, documentation, reporting, audit readiness, and coordination with program leaders.

• Lead the development, review, negotiation, and administration of client agreements, collaboration agreements, grant and funding agreements, vendor contracts, and construction and capital-project agreements, working with legal counsel as appropriate.

• Oversee procurement, competitive bid processes, vendor selection and management, insurance, contract tracking, and other core business administration activities.

• Provide strategic oversight of information technology, cybersecurity, telecommunications, access-control systems, financial systems, and other business technology infrastructure.

• Provide leadership for environmental health and safety, laboratory safety, regulatory compliance, and enterprise and operational risk management.

• Establish and maintain appropriate policies, procedures, management systems, and internal controls to support safe, compliant, and effective operations.

• Oversee regulatory interactions, environmental reporting, audits, inspections, emergency preparedness, business continuity, and corrective actions.

• Support the sourcing and recruitment of promising science‑based startups through relationships with universities, investors, accelerators, economic‑development organizations, corporate partners, and other ecosystem stakeholders.

• Lead or coordinate due diligence on prospective client companies and applicants to Innovation Space investment, grant, and acceleration programs.

• Evaluate company leadership, technology and intellectual property, market opportunity, business model, development milestones, financing strategy, operational requirements, and key execution risks.

• Support the First Fund investment program and Early‑Stage Growth Grants through pipeline development, application review, diligence, funding recommendations, agreement development, closing, milestone tracking, and post‑award monitoring.

• Partner with the President & CEO and leadership team to establish organizational priorities and translate strategy into operating plans, budgets, systems, capabilities, and measurable results.

• Lead and develop a multidisciplinary team of employees, contractors, and external service providers across a broad range of technical, financial, and business functions.

• Build effective relationships across the Innovation Space ecosystem, including DuPont, the University of Delaware, government and funding partners, clients, investors, vendors, and other stakeholders.

• Proactively identify organizational risks, resource constraints, and opportunities for improvement and lead cross‑functional solutions.

• Partner with program leadership on grant‑funded initiatives and lead other strategic projects at the direction of the President & CEO.

• Bachelor’s degree in science, engineering, operations, or a related field, or equivalent relevant experience.

• At least 10 years of progressively responsible operational leadership experience, including leadership of multidisciplinary teams.

• Experience overseeing complex laboratories, research, engineering, manufacturing, or similarly regulated operations.

• Demonstrated financial acumen and responsibility for operating budgets, capital planning, financial performance, financial statements, internal controls, vendor management, and contract administration.

• Experience providing executive oversight of EH&S, regulatory compliance, operational risk, emergency preparedness, and business continuity in a laboratory, research, engineering, manufacturing, or similarly regulated environment.

• Strong judgment, communication, and execution skills, with the ability to move effectively between strategic leadership and hands‑on problem‑solving.

• Advanced degree in science, engineering, business, finance, or related discipline.

• Experience supporting science‑based startups, shared laboratory facilities, research organizations, or innovation ecosystems.

• Experience in a nonprofit, public‑private partnership, or multi‑stakeholder governance environment.

• Experience overseeing organizational and investment assets and working with external accounting, audit, and investment professionals.

• Familiarity with grant‑funded operations, government contracting, or federally funded programs.

Success in this role will be demonstrated by the COO’s ability to translate organizational priorities into disciplined execution while ensuring that The Innovation Space operates safely, reliably, efficiently, and at a standard that supports the success of its clients and programs. Key outcomes include:

• Ensuring safe, compliant, and reliable operation of The Innovation Space’s 130,000-square-foot laboratory, office, and collaboration facility.

• Delivering annual operating and capital plans within approved budgets while strengthening financial discipline, cost management, and long‑term resource planning.

• Providing responsive, high‑quality laboratories, facilities, scientific support, technology, and administrative services that enable client companies and programs to reach critical milestones.

• Establishing scalable operational systems, policies, performance measures, and service standards that support organizational growth and continuous improvement.

• Maintaining strong readiness for audits, regulatory inspections, emergencies, business interruptions, and other operational risks.

• Building and developing a collaborative, accountable, and high‑performing multidisciplinary team.

• Partnering with the President & CEO and Chief Growth Officer to build a strong pipeline of promising science‑based companies and expand participation in The Innovation Space’s facilities, programs, and funding opportunities.

• Serving as a trusted strategic partner to the President & CEO, Board, founding partners, clients, and other stakeholders while effectively balancing strategic priorities with hands‑on operational leadership.

#LI-EH1

Join our Talent Community to stay connected with us!

DuPont is an equal opportunity employer. Qualified applicants will be considered without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability or any other protected class. If you need a reasonable accommodation to search or apply for a position, please visit our Accessibility Page for Contact Information.

DuPont offers a comprehensive pay and benefits package. To learn more visit the Compensation and Benefits page.