ZipRecruiter

Log In

1

Cell Line Development Scientist Jobs (NOW HIRING)

RXinsider LTD.

NY · On-site

Thermo Fisher Scientific Inc. is seeking a highly motivated individual with strong work behaviors ... Execute mammalian cell line development workflows, including transfection, stable pool generation ...

New

next page

Showing results 1-20

All JobsScience JobsBiology JobsBiologist JobsCell Line Development Scientist Jobs

Cell Line Development Scientist information

See salary details

$20

$38

$61

How much do cell line development scientist jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for cell line development scientist in the United States is $38.66, according to ZipRecruiter salary data. Most workers in this role earn between $28.37 and $46.15 per hour, depending on experience, location, and employer.

What does a cell line development scientist do?

A Cell Line Development Scientist is responsible for creating and optimizing cell lines used in the production of biopharmaceuticals, such as therapeutic proteins and monoclonal antibodies. Their work involves selecting, engineering, and characterizing cell lines to ensure high productivity, stability, and quality of the desired product. They use advanced techniques in molecular biology, cell culture, and genetic engineering to achieve these goals. Additionally, they document and analyze data, comply with regulatory standards, and collaborate with other departments to support drug development processes.

What are the key skills and qualifications needed to thrive as a cell line development scientist, and why are they important?

To thrive as a Cell Line Development Scientist, you need expertise in molecular and cell biology, mammalian cell culture, and a relevant life sciences degree (often a PhD or MSc). Experience with cloning, gene editing tools (like CRISPR), bioreactors, and data analysis software such as FlowJo or JMP is typically required. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills distinguish top performers in this role. These competencies are crucial for developing high-quality cell lines efficiently, ensuring robust research outcomes and supporting biopharmaceutical production.

What are some common challenges faced by cell line development scientists during the cell line selection process?

Cell Line Development Scientists often encounter challenges such as ensuring high productivity and stability of the selected cell line, dealing with genetic drift over multiple passages, and minimizing variability in protein expression. Achieving regulatory compliance and thorough documentation is also critical, as processes must be traceable and reproducible. Collaboration with upstream and downstream process teams is essential to address issues early and optimize cell lines for large-scale manufacturing requirements.

What is the difference between Cell Line Development Scientist vs Research Associate in Biotech?

AspectCell Line Development ScientistResearch Associate in Biotech
Required CredentialsBachelor's/Master's in Life Sciences, PhD often preferredBachelor's or Master's in related field
Work EnvironmentLaboratories focused on cell line creation and optimizationGeneral biotech or research labs, supporting various projects
Employer & Industry UsageBiotech and pharmaceutical companies, research institutionsBiotech firms, research organizations, academic labs
Common Search & ComparisonCell Line Development Scientist vs Research Associate in Biotech

The main difference is that a Cell Line Development Scientist specializes in creating and optimizing cell lines for production, requiring more advanced skills and experience. In contrast, a Research Associate in Biotech typically supports broader research activities with less focus on cell line development. Both roles are essential in biotech research but differ in scope and expertise.

More about Cell Line Development Scientist jobs

What cities are hiring for Cell Line Development Scientist jobs?

Cities with the most Cell Line Development Scientist job openings:

What states have the most Cell Line Development Scientist jobs?

States with the most job openings for Cell Line Development Scientist jobs include:

What are popular job titles related to Cell Line Development Scientist jobs?

For Cell Line Development Scientist jobs, the most frequently searched job titles are:

Cell Line Development Scientist jobs near you
Infographic showing various Cell Line Development Scientist job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 14% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution, with an average salary of $80,420 per year, or $38.7 per hour.

Cell Line Development Scientist

Oklahoma City, OK

Wheeler Bio, Inc.
Biotechnology Research and Development • 11 - 50 employees
Learn more about Wheeler Bio, Inc.external

Full-time

Posted 10 days ago

Job description

Job Title: Cell Line Development Scientist
Location: Oklahoma City, OK
Department: Process Development
Job Type: Full-Time

Position Summary:

As a Cell Line Development Scientist, you will support the development, optimization, and creation of mammalian cell lines for the manufacture of biologic drug substances. You will contribute to the design and execution of laboratory experiments, data analysis, and technical documentation.

Key Responsibilities:

·                     Perform laboratory experiments to support mammalian cell line development and upstream process development.

·                     Utilize Design of Experiments (DoE) for data analysis and experimental design.

·                     Coordinate and execute all phases of the CLD process, collaborating with downstream, analytical and formulation teams.

·                     Work cross-functionally with analytical development, MSAT, manufacturing and quality teams to drive successful technology transfer.

·                     Translate client amino acid sequences into nucleotide FASTA files to expedite DNA ordering process.

·                     Prepare buffers, media, and other solutions according to SOPs and protocols.

·                     Operate and maintain cell line development equipment including electroporation, single cell dispensing, and imaging equipment.

·                     Program and operate ambr250 microbioreactor system.

·                     Collect, analyze, and interpret experimental data; maintain accurate lab records and electronic notebooks.

·                     Present findings in internal and client meetings.

·                     Author technical reports and regulatory documentation.

·                     Complete Root Cause Analyses as needed, implementing corrective and preventative actions as needed.

·                     Mentor junior scientists and research associates in daily activities, data trending and data analysis.

·                     Follow all safety, quality, and compliance requirements.

Qualifications:

Education:

·                     Bachelor's, Master's or PhD degree in Chemical Engineering, Biochemistry, Biotechnology, Biology, or related field.

Experience:

·                     4 - 8 years of hands-on experience in a bioprocessing or biopharmaceutical development environment (academic or industrial); some education qualifications may substitute for some years of experience.

·                     4 - 8 years of experience with mammalian stable cell line generation is required.

·                     Familiarity with transposon-based expression systems is a plus.

·                     Experience in a CDMO environment is preferred.

·                     Knowledge of protein purification and analytical techniques is a plus.

Skills and Knowledge:

·                     Understanding of cGMP, GLP, or other regulatory standards is preferred.

·                     Strong analytical and problem-solving skills.

·                     Good written and verbal communication skills.

·                     Ability to work both independently and in a collaborative team environment.

Physical Requirements:

·         Ability to perform lab-based tasks, including standing for long periods, working with various laboratory equipment, and handling biological samples.

·         Must be able to lift and carry equipment, reagents, and materials weighing up to 25 pounds.

Working Conditions:

  • This position requires flexibility in working hours, including potential shift work, weekends, on-call duties and holidays as necessary.
  • Work involves the handling of biological materials.