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Cell Line Development Scientist Jobs in Massachusetts

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Cell Line Development Scientist information

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How much do cell line development scientist jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for cell line development scientist in Massachusetts is $42.23, according to ZipRecruiter salary data. Most workers in this role earn between $30.96 and $50.38 per hour, depending on experience, location, and employer.

What does a cell line development scientist do?

A Cell Line Development Scientist is responsible for creating and optimizing cell lines used in the production of biopharmaceuticals, such as therapeutic proteins and monoclonal antibodies. Their work involves selecting, engineering, and characterizing cell lines to ensure high productivity, stability, and quality of the desired product. They use advanced techniques in molecular biology, cell culture, and genetic engineering to achieve these goals. Additionally, they document and analyze data, comply with regulatory standards, and collaborate with other departments to support drug development processes.

What are the key skills and qualifications needed to thrive as a cell line development scientist, and why are they important?

To thrive as a Cell Line Development Scientist, you need expertise in molecular and cell biology, mammalian cell culture, and a relevant life sciences degree (often a PhD or MSc). Experience with cloning, gene editing tools (like CRISPR), bioreactors, and data analysis software such as FlowJo or JMP is typically required. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills distinguish top performers in this role. These competencies are crucial for developing high-quality cell lines efficiently, ensuring robust research outcomes and supporting biopharmaceutical production.

What are some common challenges faced by cell line development scientists during the cell line selection process?

Cell Line Development Scientists often encounter challenges such as ensuring high productivity and stability of the selected cell line, dealing with genetic drift over multiple passages, and minimizing variability in protein expression. Achieving regulatory compliance and thorough documentation is also critical, as processes must be traceable and reproducible. Collaboration with upstream and downstream process teams is essential to address issues early and optimize cell lines for large-scale manufacturing requirements.

What is the difference between Cell Line Development Scientist vs Research Associate in Biotech?

AspectCell Line Development ScientistResearch Associate in Biotech
Required CredentialsBachelor's/Master's in Life Sciences, PhD often preferredBachelor's or Master's in related field
Work EnvironmentLaboratories focused on cell line creation and optimizationGeneral biotech or research labs, supporting various projects
Employer & Industry UsageBiotech and pharmaceutical companies, research institutionsBiotech firms, research organizations, academic labs
Common Search & ComparisonCell Line Development Scientist vs Research Associate in Biotech

The main difference is that a Cell Line Development Scientist specializes in creating and optimizing cell lines for production, requiring more advanced skills and experience. In contrast, a Research Associate in Biotech typically supports broader research activities with less focus on cell line development. Both roles are essential in biotech research but differ in scope and expertise.

What are popular job titles related to Cell Line Development Scientist jobs in Massachusetts?

For Cell Line Development Scientist jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Cell Line Development Scientist jobs in Massachusetts look for?

The top searched job categories for Cell Line Development Scientist jobs in Massachusetts are:

What cities in Massachusetts are hiring for Cell Line Development Scientist jobs?

Cities in Massachusetts with the most Cell Line Development Scientist job openings:

Cell Line Development Scientist jobs near you
Infographic showing various Cell Line Development Scientist job openings in Massachusetts as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 16% Part Time, 1% Temporary, 3% Contract, and 1% Nights. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution, with an average salary of $87,828 per year, or $42.2 per hour.

Senior Scientist, Biologics Cell Line Development

Boston, MA • On-site

Asimov
See more jobs at Asimovexternal

$145K - $165K/yr

Full-time

Re-posted 8 days ago

Key responsibilities

  • Conduct and supervise CHO-based cell line development activities including transfection, cloning, characterization, and cell banking.

  • Drive innovation by developing improved genetic components, host cell line engineering, and process optimization for cell line development.

  • Represent the cell line development team on cross-functional projects, communicate results, and provide technical guidance to team members.

Job description

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.

We are seeking a Senior Scientist to join our Biologics Cell Line Development team in Boston, MA and help push the boundaries of biotherapeutic cell line development. This role is for a scientific innovator and a manager of junior scientists. The successful candidate will conduct & supervise CHO-based cell line development for biologic therapeutics moving into clinical development. Significant effort designing complex experimental approaches to improve expression systems and workflows through innovation and implementation of new technology is also an important part of this role.

The successful candidate will also work cross-functionally with Asimov’s synthetic biology, modeling, process development and analytical teams. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.

About the Role:

  • You’ll perform CHO cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment.

  • You’ll drive innovation through the development of improved genetic components, host cell line engineering and cell line development process optimization.

  • You’ll identify emerging practices for biologics cell line development and manufacturing to shape scientific strategies and continued innovation.

  • You’ll represent the cell line development team on cross-functional projects, making decisions for cell line activities and effectively communicating results, progress and plans.

  • You’ll represent Asimov externally, contributing to industry conferences, industry forums, filing patents, and publishing peer-reviewed manuscripts.

  • You’ll manage and mentor a team of 3+ scientists focused on CHO-based biologics CLD, providing technical direction and supporting them in their professional development.

About You:

  • 5+ years of experience in CHO-based cell line development is a must, stemming from expressing IgGs and bispecifics in an industrial CLD environment.

  • You have a Ph.D. in Biological Engineering, Cell Biology, Molecular Biology, or a related field.

  • You’re a creative problem solver never satisfied with the status quo and get excited about the opportunity to drive the creation of disruptive technology.

  • Minimum 1 year experience managing direct report(s) and providing technical guidance.

  • Don’t let this stop you from applying, but it’s a plus if you are familiar with any of the following: vector optimization to improve titer and product quality attributes for complex bispecific scaffolds; CLD process optimization; or development of automated high-throughput screening for CLD workflows.

  • Experience working with a global customer base isn’t a requirement for this role but bonus points if you have it.

We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.

Compensation Range: $145K - $165K