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Cell Line Development Scientist Jobs in Seattle, WA

Systimmune

Senior Scientist, Cell Science

Redmond, WA · On-site

$90K - $140K/yr

The Senior Scientist in the Cell Science Department is responsible for the development and ... Design and execute cell line development workflows, including vector design, transfection, clone ...

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All JobsCell Line Development Scientist JobsCell Line Development Scientist Jobs in Seattle, WA

Cell Line Development Scientist information

See Seattle, WA salary details

$23

$44

$70

How much do cell line development scientist jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for cell line development scientist in Seattle, WA is $44.00, according to ZipRecruiter salary data. Most workers in this role earn between $32.26 and $52.50 per hour, depending on experience, location, and employer.

What does a cell line development scientist do?

A Cell Line Development Scientist is responsible for creating and optimizing cell lines used in the production of biopharmaceuticals, such as therapeutic proteins and monoclonal antibodies. Their work involves selecting, engineering, and characterizing cell lines to ensure high productivity, stability, and quality of the desired product. They use advanced techniques in molecular biology, cell culture, and genetic engineering to achieve these goals. Additionally, they document and analyze data, comply with regulatory standards, and collaborate with other departments to support drug development processes.

What are the key skills and qualifications needed to thrive as a cell line development scientist, and why are they important?

To thrive as a Cell Line Development Scientist, you need expertise in molecular and cell biology, mammalian cell culture, and a relevant life sciences degree (often a PhD or MSc). Experience with cloning, gene editing tools (like CRISPR), bioreactors, and data analysis software such as FlowJo or JMP is typically required. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills distinguish top performers in this role. These competencies are crucial for developing high-quality cell lines efficiently, ensuring robust research outcomes and supporting biopharmaceutical production.

What are some common challenges faced by cell line development scientists during the cell line selection process?

Cell Line Development Scientists often encounter challenges such as ensuring high productivity and stability of the selected cell line, dealing with genetic drift over multiple passages, and minimizing variability in protein expression. Achieving regulatory compliance and thorough documentation is also critical, as processes must be traceable and reproducible. Collaboration with upstream and downstream process teams is essential to address issues early and optimize cell lines for large-scale manufacturing requirements.

What is the difference between Cell Line Development Scientist vs Research Associate in Biotech?

AspectCell Line Development ScientistResearch Associate in Biotech
Required CredentialsBachelor's/Master's in Life Sciences, PhD often preferredBachelor's or Master's in related field
Work EnvironmentLaboratories focused on cell line creation and optimizationGeneral biotech or research labs, supporting various projects
Employer & Industry UsageBiotech and pharmaceutical companies, research institutionsBiotech firms, research organizations, academic labs
Common Search & ComparisonCell Line Development Scientist vs Research Associate in Biotech

The main difference is that a Cell Line Development Scientist specializes in creating and optimizing cell lines for production, requiring more advanced skills and experience. In contrast, a Research Associate in Biotech typically supports broader research activities with less focus on cell line development. Both roles are essential in biotech research but differ in scope and expertise.

What are popular job titles related to Cell Line Development Scientist jobs in Seattle, WA?

For Cell Line Development Scientist jobs in Seattle, WA, the most frequently searched job titles are:

What job categories do people searching Cell Line Development Scientist jobs in Seattle, WA look for?

The top searched job categories for Cell Line Development Scientist jobs in Seattle, WA are:

Cell Line Development Scientist jobs near you
Infographic showing various Cell Line Development Scientist job openings in Seattle, WA as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 18% Part Time, and 3% Contract. Highlights an 90% Physical, 4% Hybrid, and 6% Remote job distribution, with an average salary of $91,520 per year, or $44 per hour.

Senior Scientist, Cell Science

Redmond, WA • On-site

SystImmune, Inc
Biotechnology Research and Development • 1 - 10 employees
Learn more about SystImmune, Incexternal

$90K - $140K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 18 days ago

Job description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
The Senior Scientist in the Cell Science Department is responsible for the development and optimization of CHO-based processes for the production of biotherapeutics. This role requires broad expertise and the ability to contribute to both drug discovery and development projects. A strong interest in bench work and hands-on experience with mammalian cell culture is essential.
This position requires a full-time onsite presence at our Redmond, WA location.
Responsibilities:
  • Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression.
  • Perform cell culture experiments involving mammalian cells (e.g., CHO cells) under sterile, aseptic conditions.
  • Develop and optimize expression systems, including promoters, selection markers, and gene amplification strategies for high-yield production.
  • Screen and characterize clones for productivity, stability, growth characteristics, and product quality attributes using molecular and biochemical assays.
  • Collaborate with project teams and downstream process development scientists to execute protocols, experimental plans, critical production batches, and technology transfers.
  • Manage and prioritize multiple projects while supporting and coordinating with other departments to advance company objectives and develop scalable, robust culture processes.
  • Write and review Standard Operating Procedures (SOPs) and technical reports for regulatory filings.
  • Prepare process transfer documents and cGMP documentation to support the successful implementation of process technologies in clinical and commercial manufacturing operations.
  • Collaborate with R&D and the manufacturing team in China, participating in meetings and providing technical support as needed.
  • Availability to work weekend and holiday shifts, as required.
  • Perform other duties as assigned.

Qualifications:
  • Ph.D. in Cell Biology or a related field, with 5+ years of relevant experience in the pharmaceutical or biotechnology industry.
  • Strong scientific background in recombinant protein expression, cell line development, cellular metabolism, and media optimization.
  • Experience in both early- and late-stage bioreactor operations, mammalian stable cell line development, and upstream process development is preferred.
  • Demonstrated expertise in advanced technologies for cell line development, with a focus on antibody production.
  • Strong knowledge of FDA regulations and other global health authority requirements related to Investigational New Drug (IND) applications, particularly those concerning single stable clone selection and characterization.
  • Excellent written, verbal, and interpersonal communication skills.
  • Proven ability to perform effectively under pressure, meet tight deadlines, and adapt to shifting project priorities and requirements.
  • Experience with high-throughput automated workstations for clone selection is highly desirable.
Compensation and Benefits:
The expected base salary range for this position is $90,000 - $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

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