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Cell Based Potency Assay Jobs (NOW HIRING)

Vrtx

Quality Control Senior Specialist

Boston, MA

$94K - $141K/yr

... and cell-based potency assay, etc. * Participate in delivery of appropriate documentation to support transfer, such as SOPs, qualification/validation protocols and reports, and training of QC ...

Lumencor

Cell-Based Assay Scientist

Beaverton, OR · On-site

$36.75 - $46/hr

The Cell-Based Assay Scientist uses specialized laboratory skills and technical knowledge to support Lumencor's hardware, software and reagent products related to cell-based assays. These activities ...

Cellares

Quality Control Analyst

Bridgewater, NJ · On-site

$90K - $210K/yr

Work with cell therapy products and associated assays (dPCR, qPCR, cell-based potency assays, proliferation assays, ELISA, flow cytometry assays, etc.) * Perform timely and accurate peer review of ...

Novartis

Associate Expert Potency

East Hanover, NJ

$84K - $126K/yr

Participate in method development and qualification of cell-based potency assays suitable for both in-process and drug product (DP) lot release and quality attribute assessment for AAV and LVV viral ...

Immatics NV

Quality Control Analyst I

Houston, TX

$23 - $30.75/hr

Experience with cell-based potency assays and microbiological methods * Familiarity with equipment qualification/validation and assay validation processes * Proficiencyin data analysis and ...

Cellares

Senior Analytical Transfer Scientist

Bridgewater, NJ · On-site

$93K - $127K/yr

Strong experience with bioanalytical techniques, including qPCR/ddPCR, flow cytometry, ELISA, cell-based potency assays, and viral vector assays (AAV, lentivirus) * Experience in method development ...

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All JobsCell Based Potency Assay Jobs

Cell Based Potency Assay information

What are some common challenges faced when developing and validating cell-based potency assays in a laboratory setting?

Developing and validating cell-based potency assays can be challenging due to the inherent biological variability of living cells, which can impact assay reproducibility and consistency. Additionally, optimizing assay conditions—such as cell passage number, incubation times, and reagent quality—requires careful attention to detail. Collaboration across multidisciplinary teams, including scientists, quality control, and regulatory affairs, is often necessary to ensure the assay meets rigorous industry and compliance standards. Successful candidates should be comfortable troubleshooting technical issues and adapting protocols to achieve reliable results.

What are the key skills and qualifications needed to thrive as a Cell Based Potency Assay Scientist, and why are they important?

To excel as a Cell Based Potency Assay Scientist, you need a solid background in cellular biology, assay development, and quantitative analysis, usually supported by a degree in life sciences or a related field. Familiarity with laboratory instruments like flow cytometers, plate readers, and proficiency in data analysis software such as GraphPad Prism are typically required, along with knowledge of GMP/GLP standards. Attention to detail, strong problem-solving abilities, and effective communication skills are essential soft skills in this role. These competencies ensure accurate assay results, regulatory compliance, and clear collaboration with cross-functional teams in biopharmaceutical development.

What are cell based potency assays?

Cell based potency assays are laboratory tests that use living cells to measure the biological activity of a drug, vaccine, or biologic product. These assays help determine how effective a compound is in producing a desired cellular response, making them crucial for drug development and quality control. By closely mimicking the drug’s mechanism of action in the body, they provide more relevant information about efficacy and safety compared to non-cellular assays.

What is the difference between Cell Based Potency Assay vs Cell Culture Technician?

AspectCell Based Potency AssayCell Culture Technician
Primary ResponsibilitiesAssessing the biological activity of products using cell-based methodsMaintaining and preparing cell cultures for various experiments
Required SkillsKnowledge of assay development, data analysis, cell biology techniquesCell culture techniques, aseptic handling, media preparation
Work EnvironmentLaboratories focused on assay validation and quality controlCell culture labs, manufacturing, or research facilities
Common CertificationsBiotech or laboratory certifications, cell biology trainingCell culture training, laboratory safety certifications

While both roles involve working with cells, the Cell Based Potency Assay specialist focuses on developing and performing assays to measure product activity, whereas the Cell Culture Technician primarily prepares and maintains cell cultures. The assay role requires analytical skills and assay-specific knowledge, while the technician role emphasizes cell handling and maintenance skills.

More about Cell Based Potency Assay jobs
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What job categories do people searching Cell Based Potency Assay jobs look for? The top searched job categories for Cell Based Potency Assay jobs are:
Cell Based Potency Assay jobs near you
Infographic showing various Cell Based Potency Assay job openings in the United States as of June 2026, with employment types broken down into 2% Internship, 27% As Needed, and 71% Full Time. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution.

Quality Control Senior Specialist

Vrtx

Boston, MA

$94K - $141K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 24 days ago

Job description

Job Description

General position summary:

The Senior Specialist, Quality Control provides technical support for Type 1 Diabetes (T1D) Cell and Casgevy Quality Control (QC). This includes execution and support of analytical method transfers, qualification, validation and training to both internal QC and to external contract development and manufacturing organizations (CDMO).

This position reports directly to the Quality Control Senior Manager, VCGT.

Key Responsibilities:

The responsibilities of this position may include, but are not limited to, the following:

  • Execute and support analytical method technical transfer, qualification, validation both internally and externally including, flow cytometry, qPCR, cell count and viability, ELISA, and cell-based potency assay, etc.
  • Participate in delivery of appropriate documentation to support transfer, such as SOPs, qualification/validation protocols and reports, and training of QC analysts.
  • Support QC in investigation of assay related issues, Out-of-Specification, change controls, and deviations/CAPAs.
  • Support generation and qualification of assay controls, standards, and critical reagents.
  • Lead data trending, invalid reporting, and continuous improvement.

Minimum qualifications:

Knowledge and Skills:

  • Demonstrated solid knowledge and skills in multiple analytical techniques such as flow cytometry, cell-based assays, qPCR, and ELISA.
  • Strong technical communication and technical writing skills.
  • Proficient in MS Office and statistical analysis software, e.g. GraphPad and JMP. Familiarity with project management tools is a plus.
  • Ability to handle multiple priorities and deliverables in a timely manner and attention to detail.
  • Ability to work independently and in a team environment.
  • Self-motivated individual with a can-do attitude and problem-solving skills.

Education and Experience:

  • Bachelor's or Master's degree in biology, biochemistry, microbiology, or other related sciences, is required.
  • At least 2-5 years of experience in the pharmaceutical/biopharmaceutical industry, or the equivalent combination of education and experience.
  • Experience in analytical Quality Control, method development, method transfer/qualification/validation, or technical support is required, preferably in cell-based therapy.

Pay Range:

$94,200 - $141,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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