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Cell Based Potency Assay Jobs in Missouri (NOW HIRING)

Bench Scientist

Chesterfield, MO · On-site

$35 - $43.75/hr

Qualifications Experience with ELISA, Cell-Based assays, Luminex (or Bioplex), cell culture, DNA (qPCR) method development, and method qualification. Must have ELISA based experience in ...

Associate Scientist II

Saint Charles, MO · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

This role will conduct industry leading cell-based and analytical assays in a laboratory setting with automated and classical methods. Associate Scientist II responsibilities include, but are not ...

Associate Scientist II

Saint Charles, MO

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

This role will conduct industry leading cell-based and analytical assays in a laboratory setting with automated and classical methods. Associate Scientist II responsibilities include, but are not ...

Associate Scientist II

Saint Charles, MO · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

This role will conduct industry leading cell-based and analytical assays in a laboratory setting with automated and classical methods. Associate Scientist II responsibilities include, but are not ...

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Senior Scientist

Saint Louis, MO · On-site

$90K - $125K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

You'll run the cell-based and biochemical assays that drive our pipelines, then help turn that data into signal our computational platform can learn from. Mostly bench work, but analytical ...

Proficiency in the design and execution of assays including several of the following: o Plate based assays/medium to high throughput screening o Mammalian cell culture and cell-based assays using ...

Scientist - Bioassay

Columbia, MO · On-site

$33.50 - $42/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Experience in cell, molecular, and immune assays; including cell-based assays, ELISAs, electrophoresis, WB and PCR techniques. * Strong background in cell and molecular biology. * Experience with GLP ...

Scientist - Bioassay

Columbia, MO · On-site

$33.50 - $42/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Experience in cell, molecular, and immune assays; including cell-based assays, ELISAs, electrophoresis, WB and PCR techniques. * Strong background in cell and molecular biology. * Experience with GLP ...

$16.92 - $26.44/hr

  • Medical

  • Retirement

  • PTO

PCR, gene cloning, DNA/RNA purification, western blotting, transfection, protein expression/analysis, microscopy, and cell-based functional assays. * Ability to adopt new laboratory techniques and ...

Director/Senior Director, Immunology

California, MO · On-site

$210 - $300/hr

  • Medical

  • Life

  • Retirement

  • PTO

This role is based at our San Diego headquarters. KEY RESPONSIBILITIES * Program and cross ... Experience developing and transferring robust assay cascades to CROs or automation/HTS platforms ...

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Cell Based Potency Assay information

What are cell based potency assays?

Cell based potency assays are laboratory tests that use living cells to measure the biological activity of a drug, vaccine, or biologic product. These assays help determine how effective a compound is in producing a desired cellular response, making them crucial for drug development and quality control. By closely mimicking the drug’s mechanism of action in the body, they provide more relevant information about efficacy and safety compared to non-cellular assays.

What are some common challenges faced when developing and validating cell based potency assays in a laboratory setting?

Developing and validating cell-based potency assays can be challenging due to the inherent biological variability of living cells, which can impact assay reproducibility and consistency. Additionally, optimizing assay conditions—such as cell passage number, incubation times, and reagent quality—requires careful attention to detail. Collaboration across multidisciplinary teams, including scientists, quality control, and regulatory affairs, is often necessary to ensure the assay meets rigorous industry and compliance standards. Successful candidates should be comfortable troubleshooting technical issues and adapting protocols to achieve reliable results.

What are the key skills and qualifications needed to thrive as a cell based potency assay scientist, and why are they important?

To excel as a Cell Based Potency Assay Scientist, you need a solid background in cellular biology, assay development, and quantitative analysis, usually supported by a degree in life sciences or a related field. Familiarity with laboratory instruments like flow cytometers, plate readers, and proficiency in data analysis software such as GraphPad Prism are typically required, along with knowledge of GMP/GLP standards. Attention to detail, strong problem-solving abilities, and effective communication skills are essential soft skills in this role. These competencies ensure accurate assay results, regulatory compliance, and clear collaboration with cross-functional teams in biopharmaceutical development.

What is the difference between Cell Based Potency Assay vs Cell Culture Technician?

AspectCell Based Potency AssayCell Culture Technician
Primary ResponsibilitiesAssessing the biological activity of products using cell-based methodsMaintaining and preparing cell cultures for various experiments
Required SkillsKnowledge of assay development, data analysis, cell biology techniquesCell culture techniques, aseptic handling, media preparation
Work EnvironmentLaboratories focused on assay validation and quality controlCell culture labs, manufacturing, or research facilities
Common CertificationsBiotech or laboratory certifications, cell biology trainingCell culture training, laboratory safety certifications

While both roles involve working with cells, the Cell Based Potency Assay specialist focuses on developing and performing assays to measure product activity, whereas the Cell Culture Technician primarily prepares and maintains cell cultures. The assay role requires analytical skills and assay-specific knowledge, while the technician role emphasizes cell handling and maintenance skills.

What job categories do people searching Cell Based Potency Assay jobs in Missouri look for?

The top searched job categories for Cell Based Potency Assay jobs in Missouri are:

What cities in Missouri are hiring for Cell Based Potency Assay jobs?

Cities in Missouri with the most Cell Based Potency Assay job openings:

Associate Scientist II - Molecular & Cellular Biology

Medvacon Life Sciences, LLC

Kansas City, MO • On-site

Full-time

Re-posted 8 days ago


Job description

TEMP TO HIRE - DURATION - 6 MONTHS - ONSITE POSITION - SHIFT - MON-FRI 8AM - 4PM.
I. Position Overview
Associate Scientist II is primarily responsible for testing samples, drafting methods and reporting data under cGMP regulatory guidance for Large Molecules/Biologics product development and related stability studies.
In support of Large Molecules/Biologics Biologics Therapeutics, will execute laboratory testing using the following techniques as required:
§ Mammalian cell culture
§ Sterile technique
§ In vitro cell based assays (e.g., reporter gene bioassay, cell titer glo proliferation bioassay, etc.) § ELISA assays, quantitative and potency (fluorescence, luminescence, colorimetric, MSD) § Molecular biology (e.g., qPCR, PCR, etc.) § Kinetic binding assessment (e.g., BLI or SPR) § Flow cytometry § Other technologies/methodologies as required by management
II. Essential Functions
• Reads and follows Standard Operating procedures with attention to details
• Successfully trains on 1-2 methods and/or techniques mentioned above and performs adhoc sample testing activities under cGMP as required
• Applies basic scientific and laboratory concepts and theories related to specific testing in the group
• Follow cGMP requirements for legible, accurate and thorough documentation to meet regulatory compliance. Supports drafting of simple methods, method forms and result reports.
• Adheres to policies, processes, and procedures for operating laboratory equipment in a safe and compliant manner
• Understands the culture, programs, and communication processes regarding quality, safety, and ethical practices
• All other duties as assigned
III. Position Requirements
Education and Experience:
• Bachelor’s Degree in Life Sciences or Physical Science field. No work experience required
Knowledge/Skills Requirements:
• Has basic knowledge of the principles and concepts of a discipline (e.g., Biology, Chemistry, Biochemistry).
• Excellent written and verbal communications skills with internal customers, colleagues, and supervisor
• Well organized with ability to multitask and be flexible with daily work schedule
• Ability to work effectively under pressure to meet deadlines
• Ability to pay attention to detail and exhibit critical thinking
 

Important Notice: Protecting Your Information
Medvacon Talent Acquisition only conducts initial video interviews via Microsoft Teams or Zoom. All communication will come from an email address ending in @medvacon.com. If you receive a message that seems suspicious or is not from our official domain, please report it immediately to jobs@medvacon.com.

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