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Biotransformation Jobs (NOW HIRING)

Demonstrated ability to perform specimen processing, extraction, and quantification of biologics, small molecules, ADCs, and smallmolecule payloads, including biotransformation analysis.

Senior Scientist I is responsible to carry on advanced metabolite identification and elucidation, report writing in the metabolism-biotransformation function. Deliver high quality data in a timely ...

Head of DMPK

New York, NY · On-site

$321K - $402K/yr

Knowledge of biotransformation and metabolic pathways. * Extensive experience in working with external collaborators in all shapes and forms (CROs, SMEs, Large Pharma) Working Location & Compensation:

The drug biotransformation core serves to characterize drug disposition pathways along with the consequences of drug metabolizing enzyme (DME) polymorphisms in subcellular systems derived from ...

Senior Scientist I is responsible to carry on advanced metabolite identification and elucidation, report writing in the metabolism-biotransformation function. Deliver high quality data in a timely ...

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Biotransformation information

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How much do biotransformation jobs pay per hour?

As of Jul 15, 2026, the average hourly pay for biotransformation in the United States is $30.99, according to ZipRecruiter salary data. Most workers in this role earn between $24.04 and $35.58 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Biotransformation Scientist, and why are they important?

To thrive as a Biotransformation Scientist, you need a strong background in biochemistry, pharmacology, and analytical chemistry, typically supported by an advanced degree (M.S. or Ph.D.) in a related field. Familiarity with analytical tools such as LC-MS/MS, in vitro/in vivo assay systems, and specialized data analysis software is essential. Strong problem-solving skills, attention to detail, and effective communication are crucial soft skills for interpreting complex data and collaborating with multidisciplinary teams. These skills ensure accurate drug metabolism profiling, regulatory compliance, and the advancement of pharmaceutical research.

What is the difference between Biotransformation vs Pharmacologist?

AspectBiotransformationPharmacologist
Required CredentialsBachelor's or Master's in Chemistry, Biochemistry, or related fieldsDoctorate (PhD) in Pharmacology or related discipline
Work EnvironmentLaboratories, pharmaceutical companies, research institutionsResearch labs, academia, pharmaceutical industry
Industry UsageDrug metabolism, environmental science, biotechnologyDrug development, clinical research, toxicology

Biotransformation involves the chemical modification of substances within the body, primarily focusing on drug metabolism processes. Pharmacologists study the effects, mechanisms, and interactions of drugs, often including biotransformation as part of their research. While biotransformation specialists focus on how substances are processed, pharmacologists have a broader scope, encompassing drug action and therapeutic effects.

What is biotransformation?

Biotransformation refers to the chemical modification of compounds, such as drugs or pollutants, by living organisms or their enzymes. This process is essential in fields like pharmacology, where it helps determine how the body metabolizes medications, and in environmental science, where it aids in breaking down environmental contaminants. Biotransformation can involve processes like oxidation, reduction, and hydrolysis, leading to the detoxification or activation of substances. Professionals in this field study these pathways to improve drug development, waste treatment, and understanding of biological systems.

What are some typical challenges faced by professionals working in biotransformation, and how can they be addressed?

Professionals in biotransformation often encounter challenges such as interpreting complex metabolic pathways, working with limited experimental data, and keeping up with evolving analytical technologies. Overcoming these challenges requires strong problem-solving skills, continuous learning, and effective collaboration with multidisciplinary teams including chemists, toxicologists, and computational biologists. Regularly participating in training sessions and scientific conferences can also help biotransformation scientists stay current with industry trends and best practices.
More about Biotransformation jobs
What cities are hiring for Biotransformation jobs? Cities with the most Biotransformation job openings:
What states have the most Biotransformation jobs? States with the most job openings for Biotransformation jobs include:
Infographic showing various Biotransformation job openings in the United States as of July 2026, with employment types broken down into 91% Full Time, 6% Part Time, and 3% Contract. Highlights an 94% Physical, and 6% Remote job distribution, with an average salary of $64,466 per year, or $31 per hour.
Scientist, Biology

Scientist, Biology

Gilead

Foster City, CA

$146K - $189K/yr

Full-time

Medical, Dental, Vision, Life, PTO

Re-posted 13 days ago


Gilead Sciences rating

9.0

Company rating: 9.0 out of 10

Based on 8 frontline employees who took The Breakroom Quiz

6th of 74 rated pharmaceutical


Job description

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job Description

At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers.

We set and achieve bold ambitions in our fight against the world's most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come.

We are seeking a skilled hands-on, lab-based Scientist to support pharmacokinetic (PK) bioanalysis of large molecules and ADCs across discovery and early development programs. This individual will play a key role in leading the establishment and execution of high-throughput bioanalytical methods working with a cross-functional team to deliver high quality decision driving data.
The ideal candidate thrives in a fast-paced, results-driven environment, with strong scientific ownership and leadership capabilities, and is eager to expand their impact beyond core bioanalysis into broader drug discovery efforts.

As a Scientist- Biology , at Gilead you will ...

Key Responsibilities

  • Lead development and establishment of high-throughput bioanalytical methods to support preclinical PK studies of large molecules and ADCs.
  • Independently design, develop, optimize and run bioanalytical assays using ligand binding and mass analytical techniques, leveraging robotic automation.
  • Independently analyze, interpret, and report bioanalytical and pharmacokinetic data with scientific rigor using industry standard analytical tools.
  • Operate and maintain analytical instruments such as LC-MS systems and ligand binding assay platforms.
  • Prepare and deliver internal scientific reports, presentations, and documentation.
  • Independently identify opportunities to improve current approaches and propose innovative solutions to expand the capabilities of the bioanalytical function.

Basic Qualifications:

  • 6+ Years with BS
  • OR 4+ Years with MS
  • OR 0+ Years with PhD/PharmD

Preferred qualifications:

  • BS with 6+ years of experience, MS with 4+ years of experience, PhD with 0+ years in Pharmaceutical Sciences, Chemistry, Biochemistry, Biology, or a related discipline.
  • 2-5 years of hands-on industry experience in bioanalysis and PK.
  • Expert knowledge of standard ligand binding bioanalysis assay methods, with handson experience in immunoprecipitation, enzymatic digestion, LC-MS/MS, MSD platforms, and ligand binding assays.
  • Demonstrated ability to perform specimen processing, extraction, and quantification of biologics, small molecules, ADCs, and smallmolecule payloads, including biotransformation analysis.
  • Proficiency with software for non-compartmental pharmacokinetic data analysis such as Phoenix NonWinLin.
  • Strong organizational skills, attention to detail, and the ability to manage time effectively in both independent and collaborative settings.
  • Experience in standardizing and implementing bioanalytical methods.
  • Proficiency with lab automation.
  • Experience with in vitro screening assay technologies.
  • Familiarity with HTS (96/384/1536-well formats) and laboratory automation.

Core Competencies

  • Thrive in fast-paced environment.
  • Strong ownership and accountability.
  • Critical thinking and problem solving.
  • Detail-oriented with big-picture thinking.
  • Strong work ethic.
  • Effective multitasking.
  • Excellent communication skills.
  • Collaborative and open-minded.


The salary range for this position is: $146,540.00 - $189,640.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.


For jobs in the United States:

Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability,genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.comfor assistance.


For more information about equal employment opportunity protections, please view the'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT


Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.


Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.


For Current Gilead Employees and Contractors:

Please apply via the Internal Career Opportunities portal in Workday.


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