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Biotransformation Jobs (NOW HIRING)

Frontage Laboratories

Scientist

Hayward, CA · On-site

$80K - $110K/yr

Strong expertise in drug metabolism and biotransformation, with hands-on experience in metabolite identification using LC-MS/MS and HRMS. * Demonstrated ability to analyze and interpret complex mass ...

Uottawa

APTPUO-Fall 2026-BPS3102-A00

Campus, IL

$239.47/hr

The fundamental principles of toxicology and pharmacology (route of exposure/administration, absorption, distribution, biotransformation, site and mechanism of action, elimination) and common ...

Gilead

Scientist, Biology

Foster City, CA · On-site

$146K - $189K/yr

Demonstrated ability to perform specimen processing, extraction, and quantification of biologics, small molecules, ADCs, and smallmolecule payloads, including biotransformation analysis.

WuXi AppTec

Senior Scientist I

Cranbury, NJ · On-site

$93K - $127K/yr

Overview Senior Scientist I is responsible to carry on advanced metabolite identification and elucidation, report writing in the metabolism-biotransformation function. Deliver high quality data in a ...

Recursion

Head of DMPK

New York, NY · Hybrid

$321K - $402K/yr

Knowledge of biotransformation and metabolic pathways. * Extensive experience in working with external collaborators in all shapes and forms (CROs, SMEs, Large Pharma) Working Location & Compensation:

Gilead

Scientist, Biology

Foster City, CA

$146K - $189K/yr

Demonstrated ability to perform specimen processing, extraction, and quantification of biologics, small molecules, ADCs, and smallmolecule payloads, including biotransformation analysis.

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Biotransformation information

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$17

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How much do biotransformation jobs pay per hour?

As of Jul 15, 2026, the average hourly pay for biotransformation in the United States is $30.99, according to ZipRecruiter salary data. Most workers in this role earn between $24.04 and $35.58 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Biotransformation Scientist, and why are they important?

To thrive as a Biotransformation Scientist, you need a strong background in biochemistry, pharmacology, and analytical chemistry, typically supported by an advanced degree (M.S. or Ph.D.) in a related field. Familiarity with analytical tools such as LC-MS/MS, in vitro/in vivo assay systems, and specialized data analysis software is essential. Strong problem-solving skills, attention to detail, and effective communication are crucial soft skills for interpreting complex data and collaborating with multidisciplinary teams. These skills ensure accurate drug metabolism profiling, regulatory compliance, and the advancement of pharmaceutical research.

What is the difference between Biotransformation vs Pharmacologist?

AspectBiotransformationPharmacologist
Required CredentialsBachelor's or Master's in Chemistry, Biochemistry, or related fieldsDoctorate (PhD) in Pharmacology or related discipline
Work EnvironmentLaboratories, pharmaceutical companies, research institutionsResearch labs, academia, pharmaceutical industry
Industry UsageDrug metabolism, environmental science, biotechnologyDrug development, clinical research, toxicology

Biotransformation involves the chemical modification of substances within the body, primarily focusing on drug metabolism processes. Pharmacologists study the effects, mechanisms, and interactions of drugs, often including biotransformation as part of their research. While biotransformation specialists focus on how substances are processed, pharmacologists have a broader scope, encompassing drug action and therapeutic effects.

What is biotransformation?

Biotransformation refers to the chemical modification of compounds, such as drugs or pollutants, by living organisms or their enzymes. This process is essential in fields like pharmacology, where it helps determine how the body metabolizes medications, and in environmental science, where it aids in breaking down environmental contaminants. Biotransformation can involve processes like oxidation, reduction, and hydrolysis, leading to the detoxification or activation of substances. Professionals in this field study these pathways to improve drug development, waste treatment, and understanding of biological systems.

What are some typical challenges faced by professionals working in biotransformation, and how can they be addressed?

Professionals in biotransformation often encounter challenges such as interpreting complex metabolic pathways, working with limited experimental data, and keeping up with evolving analytical technologies. Overcoming these challenges requires strong problem-solving skills, continuous learning, and effective collaboration with multidisciplinary teams including chemists, toxicologists, and computational biologists. Regularly participating in training sessions and scientific conferences can also help biotransformation scientists stay current with industry trends and best practices.
More about Biotransformation jobs
What cities are hiring for Biotransformation jobs? Cities with the most Biotransformation job openings:
What states have the most Biotransformation jobs? States with the most job openings for Biotransformation jobs include:
What job categories do people searching Biotransformation jobs look for? The top searched job categories for Biotransformation jobs are:
Biotransformation jobs near you
Infographic showing various Biotransformation job openings in the United States as of July 2026, with employment types broken down into 91% Full Time, 6% Part Time, and 3% Contract. Highlights an 94% Physical, and 6% Remote job distribution, with an average salary of $64,466 per year, or $31 per hour.
Scientist, ADME & BioAnalytical

Scientist, ADME & BioAnalytical

Monte Rosa Therapeutics, Inc

Boston, MA

Full-time

Re-posted 21 days ago

Job description

Overview

Monte Rosa Therapeutics (MRT) seeks to recruit an experienced, creative and highly talented DMPK and ADME Scientist who is eager will assit in leading the discovery and development effort to grow the drug pipelines, as well as help lead external GxP compliance research efforts. The Scientist will work MRTx colleagues to participate in all stages of DMPK  and ADME assessments, from initial compound screening through to IND and NDA regulatory submissions. Working with Research, Bioanalytical and Clinical Science subject matter experts, provides scientific expertise to ensure that clinical candidates with acceptable drug development characteristics are identified and appropriately characterized. Represents Preclinical Development on Research and Development teams and regularly interfaces with internal and external colleagues to ensure timely and accurate dissemination of DMPK and ADME findings

Responsibilities
  • Work closely with the medicinal chemistry team, the Scientist Position will lead the Nonclinical Development efforts in troubleshooting and guidance to the discovery project team with a particular focus on optimizing properties for oral administration
  • Represent Nonclinical Development to project teams and present our work in the interpretation of ADME experimental data related to the in vitro and in vivo animal PK and biotransformation.
  • Continually learn in vitro ADME and in vivo animal PK analysis (Winnolin)
  • Coordinate outsourced in vitro and in vivo DMPK studies
  • Explore new technologies and capabilities in discovery DMPK space
  • Strong written and oral communication to support internal communication of data, study reports and regulatory documentation.
  • Ability to work on multiple projects in a matrixed organizational structure
  • Aide the Nonclinical Development & Clinical Pharmacology team's activities across multiple project phases, including lead discovery, lead optimization, and regulatory filings.
Qualifications
  • 7+ years of drug discovery industry experience in Drug Metabolism, Pharmacokinetics, Pharmaceutical Chemistry, Toxicology, or a related scientific discipline.
  • Effective management of internal and external collaborations/service providers (CROs)
  • Build relationships with peers and partners outside of Nonclinical Development & Clinical Pharmacology to enable high team performance.
  • Demonstrates novel, innovative solutions to challenging problems using an extremely high degree of scientific discretion, intuition, and integrity.
  • Strong collaboration and innovative skills across subject areas representing DMPK as a project team representative within the core team is a key requirement.

Experience in the design, conduct, and interpretation of in vitro and in vivo ADME and animal PK studies

Employment Type: FULL_TIME

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