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Biotech Process Engineer Jobs in Chicago, IL (NOW HIRING)

Clayco

Process Engineer

Chicago, IL · On-site

$135K - $185K/yr

The Process Engineer works closely with clients, process architects, utilities engineers ... pharmaceutical, biotechnology, or advanced therapy environments. * Demonstrated experience ...

Clayco (LJC)

Process Engineer

Chicago, IL

The Process Engineer works closely with clients, process architects, utilities engineers ... pharmaceutical, biotechnology, or advanced therapy environments. * Demonstrated experience ...

Clayco (LJC)

Process Engineer

Chicago, IL · On-site

The Process Engineer works closely with clients, process architects, utilities engineers ... pharmaceutical, biotechnology, or advanced therapy environments. * Demonstrated experience ...

Clayco (LJC)

Process Engineer

Chicago, IL

The Process Engineer works closely with clients, process architects, utilities engineers ... pharmaceutical, biotechnology, or advanced therapy environments. * Demonstrated experience ...

Clayco (LJC)

Process Engineer

Chicago, IL

The Process Engineer works closely with clients, process architects, utilities engineers ... pharmaceutical, biotechnology, or advanced therapy environments. * Demonstrated experience ...

Clayco (LJC)

Process Engineer

Chicago, IL · On-site

The Process Engineer works closely with clients, process architects, utilities engineers ... pharmaceutical, biotechnology, or advanced therapy environments. * Demonstrated experience ...

Sterling Engineering Inc.

Project Engineer

Waukegan, IL · On-site

$75 - $85/hr

... Process Engineering and/or Project Engineering experience • Must have GMP - regulated or Pharmaceutical, API, biotech, fine chemical, or specialty chemical manufacturing experience • Must have ...

Danaher

Senior Engineer, Process Validation

Chicago, IL · On-site +1

$100K - $130K/yr

... biotechnology? At Aldevron, one of Danaher's 15+ operating companies, our work saves lives-and we ... The Senior Engineer, Process Validation is responsible for leading & supporting internal and ...

Danaher

Senior Engineer, Process Validation

Chicago, IL · On-site +1

$100K - $130K/yr

... biotechnology? At Aldevron, one of Danaher's 15+ operating companies, our work saves lives-and we ... The Senior Engineer, Process Validation is responsible for leading & supporting internal and ...

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Showing results 1-20

All JobsBiotech Process Engineer JobsBiotech Process Engineer Jobs in Chicago, IL

Biotech Process Engineer information

See Chicago, IL salary details

$51K

$94.8K

$146.8K

How much do biotech process engineer jobs pay per year?

As of Jul 27, 2026, the average yearly pay for biotech process engineer in Chicago, IL is $94,792.00, according to ZipRecruiter salary data. Most workers in this role earn between $76,700.00 and $106,100.00 per year, depending on experience, location, and employer.

What engineers make $300,000 a year?

Senior biotech process engineers with extensive experience, advanced skills in bioprocessing, and leadership roles can earn $300,000 or more annually. High compensation is often associated with working in specialized areas, managing large-scale production, or holding executive-level responsibilities in the biotech industry.

What is process engineering in biotechnology?

Process engineering in biotechnology involves designing, developing, and optimizing manufacturing processes for biological products such as pharmaceuticals, vaccines, and biofuels. Biotech process engineers work with equipment like bioreactors and use techniques such as fermentation and purification to ensure efficient, scalable, and compliant production. They often require knowledge of chemical engineering principles, laboratory skills, and familiarity with regulatory standards.

What engineers make $500,000?

Senior biotech process engineers with extensive experience, advanced skills in bioprocessing, and leadership roles can earn salaries approaching or exceeding $500,000, especially in high-cost-of-living areas or with bonuses and stock options. Such compensation typically requires a combination of technical expertise, management responsibilities, and industry demand.

What is the difference between Biotech Process Engineer vs Biotech Manufacturing Technician?

AspectBiotech Process EngineerBiotech Manufacturing Technician
CredentialsBachelor's degree in biotech, chemical engineering, or related field; often requires experience in process designAssociate's or bachelor's degree; focus on operational skills and equipment handling
Work EnvironmentDesigning, optimizing, and overseeing production processes in labs or manufacturing facilitiesOperating and maintaining equipment on the manufacturing floor
Job FocusProcess development, scale-up, troubleshooting, and process improvementExecuting production tasks, quality checks, and equipment setup

Biotech Process Engineers focus on designing and improving manufacturing processes, requiring technical and analytical skills. In contrast, Biotech Manufacturing Technicians handle day-to-day production operations. Both roles are essential in biotech manufacturing but differ in responsibilities and required qualifications.

What are some common challenges faced by Biotech Process Engineers during scale-up from laboratory to production?

Biotech Process Engineers often encounter challenges when scaling up processes from laboratory or pilot scale to full production. These challenges can include maintaining product consistency, ensuring process sterility, and adapting equipment to handle larger volumes without compromising yield or quality. Engineers must also collaborate closely with cross-functional teams such as quality assurance, validation, and manufacturing to implement changes efficiently and adhere to regulatory standards. Proactive problem-solving and strong communication skills are key to overcoming these hurdles and ensuring successful technology transfer.

What does a Biotech Process Engineer do?

A Biotech Process Engineer designs, develops, and optimizes processes used in the production of biological products such as pharmaceuticals, vaccines, and biofuels. They work closely with scientists and manufacturing teams to scale up lab procedures to industrial levels while ensuring product quality and regulatory compliance. Their role often involves troubleshooting equipment, improving efficiency, and implementing new technologies within biotech manufacturing environments.

What engineers make $200,000 a year?

Biotech process engineers can earn $200,000 or more annually, especially with extensive experience, advanced degrees, or leadership roles in the industry. High salaries are often associated with senior positions, specialized skills in bioprocessing, and working in competitive biotech or pharmaceutical companies.

What are the key skills and qualifications needed to thrive as a Biotech Process Engineer, and why are they important?

To thrive as a Biotech Process Engineer, you need a solid background in chemical or biochemical engineering, process design, and regulatory compliance, typically supported by a relevant bachelor's or master's degree. Familiarity with process control systems, bioprocess simulation software, and industry-standard quality systems such as cGMP is essential. Strong analytical thinking, problem-solving abilities, and effective teamwork and communication skills help you excel in cross-functional environments. These skills ensure efficient, compliant, and innovative bioprocess operations, which are critical for product quality and organizational success.
What are popular job titles related to Biotech Process Engineer jobs in Chicago, IL? For Biotech Process Engineer jobs in Chicago, IL, the most frequently searched job titles are:
What job categories do people searching Biotech Process Engineer jobs in Chicago, IL look for? The top searched job categories for Biotech Process Engineer jobs in Chicago, IL are:
Biotech Process Engineer jobs near you
Infographic showing various Biotech Process Engineer job openings in Chicago, IL as of July 2026, with employment types broken down into 100% Full Time. Highlights an 66% In-person, 17% Hybrid, and 17% Remote job distribution, with an average salary of $94,792 per year, or $45.6 per hour.
Process Engineer

Process Engineer

Clayco

Chicago, IL • On-site

$135K - $185K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 2 days ago

Clayco rating

7.5

Company rating: 7.5 out of 10

Based on 5 frontline employees who took The Breakroom Quiz

Job description

About Us
Clayco is a full-service, turnkey real estate development, master planning, architecture, engineering, and construction firm that safely delivers clients across North America the highest quality solutions on time, on budget, and above and beyond expectations. With $7.6 billion in revenue for 2024, Clayco specializes in the "art and science of building," providing fast track, efficient solutions for industrial, commercial, institutional, and residential related building projects.
About LJC
LJC Design & Engineering is a full-service architecture, engineering, and design firm committed to enhancing the quality of the human experience through integrated design. We are a team of high-energy professionals who share a passion for design, a collaborative approach, and a casual culture. We solve challenges by leveraging the collective expertise and ingenuity of the best and brightest minds across development, design, and construction.
The Role We Want You For
LJC is seeking an experienced Process Engineer to support the planning, design, and delivery of life sciences manufacturing facilities across a range of therapeutic and production modalities. This role focuses on defining process requirements, equipment needs, and operational workflows that inform facility planning and engineering design for regulated manufacturing environments.
The Process Engineer works closely with clients, process architects, utilities engineers, mechanical engineers, and construction teams to translate manufacturing processes into clear, coordinated design solutions. While experience across multiple modalities is valued, candidates with deep expertise in a specific modality are strongly encouraged to apply.
The Specifics of the Role
  • Lead or support process definition and design efforts for life sciences manufacturing facilities from early planning through construction support.
  • Define process flows, unit operations, equipment requirements, and space needs to support regulated manufacturing operations.
  • Develop process narratives, block flow diagrams, and equipment layouts that inform architectural and engineering design.
  • Collaborate with clients to understand manufacturing objectives, capacity requirements, product mix, and operational constraints.
  • Work closely with process architects and project teams to translate process requirements into compliant, efficient, and flexible facility layouts.
  • Coordinate with critical utilities, mechanical, electrical, automation, and architectural teams to align process needs with supporting systems and infrastructure.
  • Support front-end project efforts by contributing to proposals, technical narratives, and early planning concepts.
  • Participate in client meetings, technical workshops, and planning sessions related to process definition, capacity planning, and operational strategy.
  • Support compliance with applicable regulatory requirements, including GMP/GxP expectations and relevant industry guidelines.
  • Review process-related design deliverables to ensure alignment with defined process requirements and overall project objectives.
  • Participate in multidisciplinary coordination reviews to resolve process-related design challenges.
  • Stay current with emerging technologies, manufacturing platforms, and best practices across life sciences modalities.

Requirements
  • Bachelor's degree in Chemical Engineering, Biochemical Engineering, Mechanical Engineering, or a related technical field.
  • 10+ years of experience in life sciences manufacturing process engineering within pharmaceutical, biotechnology, or advanced therapy environments.
  • Demonstrated experience supporting at least one major life sciences manufacturing modality, such as:
  • Monoclonal antibodies (mAbs)
  • Fill-finish (aseptic or non-aseptic)
  • Advanced therapy medicinal products (ATMPs), including cell and gene therapies
  • mRNA
  • Vaccines
  • Active pharmaceutical ingredients (API)
  • Oral solid dosage (OSD)
  • Exposure to additional modalities, platforms, or production technologies is preferred but not required.
  • Strong understanding of regulated manufacturing processes, unit operations, and equipment typical of life sciences facilities.
  • Experience translating process requirements into facility design inputs, equipment layouts, and engineering criteria.
  • Familiarity with GMP/GxP environments and regulatory expectations.
  • Experience working in a design-build or fast-track project delivery environment preferred.
  • Strong communication skills, with the ability to engage in client-facing technical discussions and multidisciplinary coordination.
  • Ability to collaborate effectively across engineering, architectural, and construction teams.
  • Professional Engineer (PE) licensure preferred but not required.

Some Things You Should Know
  • Our clients and projects are nationwide
  • No other builder can offer the collaborative design-build approach that Clayco does.
  • We work on creative, complex, award-winning, high-profile jobs.
  • The pace is fast!

Why Clayco and LJC?
  • 2025 Best Places to Work - St. Louis Business Journal, Los Angeles Business Journal, and Phoenix Business Journal.
  • 2025 ENR Midwest - Midwest Contractor (#1).
  • 2025 ENR Top 100 Design-Build Firms - Design-Build Contractor (Top 5).
  • 2025 ENR Top 100 Green Contractors - Green Contractor (Top 3).
  • 2025 ENR Top 25 Data Center Builders - Data Center Contractor (Top 3).

Benefits
  • Discretionary Annual Bonus: Subject to company and individual performance.
  • Comprehensive Benefits Package Including: Medical, dental and vision plans, 401k, generous PTO and paid company holidays, employee assistance program, flexible spending accounts, life insurance, disability coverage, learning & development programs and more!

Compensation
  • The salary range for this position considers a wide range of factors in making compensation decisions including but not limited to: Education, qualifications, skills, training, experience, certifications, internal equity, and location. It is not typical for an individual to be hired at or near the top of the range for the role and compensation decisions are dependent on the facts and circumstances of each case. The Clayco Nationwide salary range for this position is approximately $135,000 - $185,000 +/- annually (not adjusted for location).

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