ZipRecruiter

Log In

1

Aseptic Process Engineer Jobs in Chicago, IL (NOW HIRING)

Clayco

Process Engineer

Chicago, IL · On-site

$135K - $185K/yr

The Process Engineer works closely with clients, process architects, utilities engineers ... Fill-finish (aseptic or non-aseptic) * Advanced therapy medicinal products (ATMPs), including cell ...

Clayco (LJC)

Process Engineer

Chicago, IL · On-site

The Process Engineer works closely with clients, process architects, utilities engineers ... Fill-finish (aseptic or non-aseptic) * Advanced therapy medicinal products (ATMPs), including cell ...

Clayco (LJC)

Process Engineer

Chicago, IL · On-site

The Process Engineer works closely with clients, process architects, utilities engineers ... Fill-finish (aseptic or non-aseptic) * Advanced therapy medicinal products (ATMPs), including cell ...

Clayco (LJC)

Process Engineer

Chicago, IL · On-site

The Process Engineer works closely with clients, process architects, utilities engineers ... Fill-finish (aseptic or non-aseptic) * Advanced therapy medicinal products (ATMPs), including cell ...

Clayco (LJC)

Process Engineer

Chicago, IL · On-site

The Process Engineer works closely with clients, process architects, utilities engineers ... Fill-finish (aseptic or non-aseptic) * Advanced therapy medicinal products (ATMPs), including cell ...

Clayco (LJC)

Process Engineer

Chicago, IL

The Process Engineer works closely with clients, process architects, utilities engineers ... Fill-finish (aseptic or non-aseptic) * Advanced therapy medicinal products (ATMPs), including cell ...

fairlife

Senior Dairy Processing Engineer

Chicago, IL · On-site

$107K - $138K/yr

Process design, scale-up, and optimization * Define critical process parameters, key performance ... Experience with aseptic systems and packaging interactions (commercial aseptic operations strongly ...

fairlife

Senior Dairy Processing Engineer

Chicago, IL · On-site

$107K - $138K/yr

Process design, scale-up, and optimization * Define critical process parameters, key performance ... Experience with aseptic systems and packaging interactions (commercial aseptic operations strongly ...

fairlife

Senior Dairy Processing Engineer

Chicago, IL · On-site

$107K - $138K/yr

Process design, scale-up, and optimization * Define critical process parameters, key performance ... Experience with aseptic systems and packaging interactions (commercial aseptic operations strongly ...

Danaher

Senior Engineer, Process Validation

Chicago, IL · On-site +1

$100K - $130K/yr

The Senior Engineer, Process Validation is responsible for leading & supporting internal and ... for aseptic manufacturing processes including sterile filtration, aseptic process simulation ...

Danaher

Senior Engineer, Process Validation

Chicago, IL · On-site +1

$100K - $130K/yr

The Senior Engineer, Process Validation is responsible for leading & supporting internal and ... for aseptic manufacturing processes including sterile filtration, aseptic process simulation ...

Pioneer GMP Consulting

CQV Engineer (Chicago)

Chicago, IL · On-site

$110 - $150/hr

We're seeking a CQV Engineer to join our team at Pioneer GMP Consulting and support clients across ... Experience within biologics , aseptic processing , cell & gene therapy , or other advanced therapy ...

New

next page

Showing results 1-20

All JobsAseptic Process Engineer JobsAseptic Process Engineer Jobs in Chicago, IL

Aseptic Process Engineer information

See Chicago, IL salary details

$51K

$94.8K

$146.8K

How much do aseptic process engineer jobs pay per year?

As of Sep 4, 2026, the average yearly pay for aseptic process engineer in Chicago, IL is $94,792.00, according to ZipRecruiter salary data. Most workers in this role earn between $76,700.00 and $106,100.00 per year, depending on experience, location, and employer.

What is an aseptic process engineer?

Aseptic process engineers are professionals who design, develop, and maintain sterile manufacturing systems, primarily in the pharmaceutical, biotechnology, and food industries. Their main responsibility is to ensure that products are produced in a contamination-free environment, using processes that prevent the introduction of microorganisms. This involves overseeing the design of cleanrooms, validating equipment, developing standard operating procedures, and ensuring regulatory compliance. Aseptic process engineers work closely with quality assurance teams to maintain high standards of product safety and efficacy. Their expertise is crucial for industries where product sterility is critical to consumer safety.

What are the key skills and qualifications needed to thrive as an aseptic process engineer, and why are they important?

Aseptic Process Engineers need a strong background in chemical, mechanical, or biomedical engineering, along with experience in aseptic manufacturing environments and a solid understanding of GMP regulations. Familiarity with process automation systems, sterilization equipment, and industry certifications such as Six Sigma or Lean Manufacturing are often required. Attention to detail, strong problem-solving abilities, and effective communication are vital soft skills for ensuring product quality and process efficiency. These skills are crucial for maintaining sterile conditions, regulatory compliance, and the safe production of pharmaceuticals or biotechnology products.

What are some common challenges faced by aseptic process engineers, and how can they be addressed?

Aseptic Process Engineers often encounter challenges such as maintaining strict sterility standards, troubleshooting equipment issues, and ensuring compliance with changing regulatory requirements. Addressing these challenges requires strong attention to detail, proactive communication with cross-functional teams, and staying current with industry best practices and regulations. Collaborating closely with quality assurance, production, and maintenance teams helps to identify and resolve issues quickly, ensuring that processes remain efficient and compliant.

What is the difference between Aseptic Process Engineer vs Pharmaceutical Manufacturing Technician?

AspectAseptic Process EngineerPharmaceutical Manufacturing Technician
CredentialsBachelor's degree in engineering, life sciences, or related field; GMP trainingHigh school diploma or associate degree; GMP training often required
Work EnvironmentCleanroom, sterile environments, manufacturing facilitiesManufacturing floors, production areas, sometimes cleanrooms
Industry UsageDesign, optimize, and validate aseptic processes in pharmaOperate equipment, assemble products, support manufacturing

The Aseptic Process Engineer focuses on designing and validating sterile manufacturing processes, requiring specialized engineering knowledge. In contrast, the Pharmaceutical Manufacturing Technician handles day-to-day production tasks, often with less formal education but essential for maintaining manufacturing flow. Both roles are vital in pharmaceutical production but differ in responsibilities and qualifications.

What are popular job titles related to Aseptic Process Engineer jobs in Chicago, IL?

For Aseptic Process Engineer jobs in Chicago, IL, the most frequently searched job titles are:

What job categories do people searching Aseptic Process Engineer jobs in Chicago, IL look for?

The top searched job categories for Aseptic Process Engineer jobs in Chicago, IL are:

What cities near Chicago, IL are hiring for Aseptic Process Engineer jobs?

Cities near Chicago, IL with the most Aseptic Process Engineer job openings:

Aseptic Process Engineer jobs near you
Infographic showing various Aseptic Process Engineer job openings in Chicago, IL as of August 2026, with employment types broken down into 1% As Needed, 76% Full Time, 19% Part Time, 3% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $94,792 per year, or $45.6 per hour.

Process Engineer

Clayco

Chicago, IL • On-site

$135K - $185K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 11 days ago

Clayco rating

8.6

Company rating: 8.6 out of 10

Based on 6 frontline employees who took The Breakroom Quiz

Job description

About Us
Clayco is a full-service, turnkey real estate development, master planning, architecture, engineering, and construction firm that safely delivers clients across North America the highest quality solutions on time, on budget, and above and beyond expectations. With $7.6 billion in revenue for 2024, Clayco specializes in the "art and science of building," providing fast track, efficient solutions for industrial, commercial, institutional, and residential related building projects.
About LJC
LJC Design & Engineering is a full-service architecture, engineering, and design firm committed to enhancing the quality of the human experience through integrated design. We are a team of high-energy professionals who share a passion for design, a collaborative approach, and a casual culture. We solve challenges by leveraging the collective expertise and ingenuity of the best and brightest minds across development, design, and construction.
The Role We Want You For
LJC is seeking an experienced Process Engineer to support the planning, design, and delivery of life sciences manufacturing facilities across a range of therapeutic and production modalities. This role focuses on defining process requirements, equipment needs, and operational workflows that inform facility planning and engineering design for regulated manufacturing environments.
The Process Engineer works closely with clients, process architects, utilities engineers, mechanical engineers, and construction teams to translate manufacturing processes into clear, coordinated design solutions. While experience across multiple modalities is valued, candidates with deep expertise in a specific modality are strongly encouraged to apply.
The Specifics of the Role
  • Lead or support process definition and design efforts for life sciences manufacturing facilities from early planning through construction support.
  • Define process flows, unit operations, equipment requirements, and space needs to support regulated manufacturing operations.
  • Develop process narratives, block flow diagrams, and equipment layouts that inform architectural and engineering design.
  • Collaborate with clients to understand manufacturing objectives, capacity requirements, product mix, and operational constraints.
  • Work closely with process architects and project teams to translate process requirements into compliant, efficient, and flexible facility layouts.
  • Coordinate with critical utilities, mechanical, electrical, automation, and architectural teams to align process needs with supporting systems and infrastructure.
  • Support front-end project efforts by contributing to proposals, technical narratives, and early planning concepts.
  • Participate in client meetings, technical workshops, and planning sessions related to process definition, capacity planning, and operational strategy.
  • Support compliance with applicable regulatory requirements, including GMP/GxP expectations and relevant industry guidelines.
  • Review process-related design deliverables to ensure alignment with defined process requirements and overall project objectives.
  • Participate in multidisciplinary coordination reviews to resolve process-related design challenges.
  • Stay current with emerging technologies, manufacturing platforms, and best practices across life sciences modalities.

Requirements
  • Bachelor's degree in Chemical Engineering, Biochemical Engineering, Mechanical Engineering, or a related technical field.
  • 10+ years of experience in life sciences manufacturing process engineering within pharmaceutical, biotechnology, or advanced therapy environments.
  • Demonstrated experience supporting at least one major life sciences manufacturing modality, such as:
  • Monoclonal antibodies (mAbs)
  • Fill-finish (aseptic or non-aseptic)
  • Advanced therapy medicinal products (ATMPs), including cell and gene therapies
  • mRNA
  • Vaccines
  • Active pharmaceutical ingredients (API)
  • Oral solid dosage (OSD)
  • Exposure to additional modalities, platforms, or production technologies is preferred but not required.
  • Strong understanding of regulated manufacturing processes, unit operations, and equipment typical of life sciences facilities.
  • Experience translating process requirements into facility design inputs, equipment layouts, and engineering criteria.
  • Familiarity with GMP/GxP environments and regulatory expectations.
  • Experience working in a design-build or fast-track project delivery environment preferred.
  • Strong communication skills, with the ability to engage in client-facing technical discussions and multidisciplinary coordination.
  • Ability to collaborate effectively across engineering, architectural, and construction teams.
  • Professional Engineer (PE) licensure preferred but not required.

Some Things You Should Know
  • Our clients and projects are nationwide
  • No other builder can offer the collaborative design-build approach that Clayco does.
  • We work on creative, complex, award-winning, high-profile jobs.
  • The pace is fast!

Why Clayco and LJC?
  • 2025 Best Places to Work - St. Louis Business Journal, Los Angeles Business Journal, and Phoenix Business Journal.
  • 2025 ENR Midwest - Midwest Contractor (#1).
  • 2025 ENR Top 100 Design-Build Firms - Design-Build Contractor (Top 5).
  • 2025 ENR Top 100 Green Contractors - Green Contractor (Top 3).
  • 2025 ENR Top 25 Data Center Builders - Data Center Contractor (Top 3).

Benefits
  • Discretionary Annual Bonus: Subject to company and individual performance.
  • Comprehensive Benefits Package Including: Medical, dental and vision plans, 401k, generous PTO and paid company holidays, employee assistance program, flexible spending accounts, life insurance, disability coverage, learning & development programs and more!

Compensation
  • The salary range for this position considers a wide range of factors in making compensation decisions including but not limited to: Education, qualifications, skills, training, experience, certifications, internal equity, and location. It is not typical for an individual to be hired at or near the top of the range for the role and compensation decisions are dependent on the facts and circumstances of each case. The Clayco Nationwide salary range for this position is approximately $135,000 - $185,000 +/- annually (not adjusted for location).

What Clayco employees say

Pay

Hours and flexibility

Workplace

Get the full story on Breakroom

Apply