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Biotech Process Engineer Jobs in Boston, MA (NOW HIRING)

Applications Engineer II

Brookline, MA · On-site

$109K - $131K/yr

PBS Biotech is an innovative, fast-growing biotechnology company headquartered in Camarillo ... Troubleshoot and resolve cell culture and process-related challenges in a timely manner * Provide ...

Reliability Engineer

Boston, MA

$111K - $140K/yr

... biotechnology, pharmaceutical, R&D, or another highly regulated manufacturing environment preferred. * Experience in Reliability Engineering, Facilities Engineering, Process Engineering, Plant ...

Senior Engineer, Process Validation

Boston, MA · On-site +1

$100K - $130K/yr

... biotechnology? At Aldevron, one of Danaher's 15+ operating companies, our work saves lives-and we ... The Senior Engineer, Process Validation is responsible for leading & supporting internal and ...

Senior Engineer, Process Validation

Boston, MA · On-site +1

$100K - $130K/yr

... biotechnology? At Aldevron, one of Danaher's 15+ operating companies, our work saves lives-and we ... The Senior Engineer, Process Validation is responsible for leading & supporting internal and ...

The team applies these talents across Draper's broad S&T portfolio, which spans Biotechnology, Electronic, Strategic, and Space Systems. We are seeking Sensor Signal Processing Engineers to concept ...

Project Engineer

Waltham, MA · On-site

$100K - $180K/yr

Summary ATP is building a core team of engineers to work alongside our Process and Chemistry R&D ... Background in energetics, chemicals, process/manufacturing, biotech/pharma, or another regulated ...

Showing results 41-60

Biotech Process Engineer information

See Boston, MA salary details

$53.8K

$100K

$154.8K

How much do biotech process engineer jobs pay per year?

As of Aug 16, 2026, the average yearly pay for biotech process engineer in Boston, MA is $99,968.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,900.00 and $111,900.00 per year, depending on experience, location, and employer.

What is the difference between Biotech Process Engineer vs Biotech Manufacturing Technician?

AspectBiotech Process EngineerBiotech Manufacturing Technician
CredentialsBachelor's degree in biotech, chemical engineering, or related field; often requires experience in process designAssociate's or bachelor's degree; focus on operational skills and equipment handling
Work EnvironmentDesigning, optimizing, and overseeing production processes in labs or manufacturing facilitiesOperating and maintaining equipment on the manufacturing floor
Job FocusProcess development, scale-up, troubleshooting, and process improvementExecuting production tasks, quality checks, and equipment setup

Biotech Process Engineers focus on designing and improving manufacturing processes, requiring technical and analytical skills. In contrast, Biotech Manufacturing Technicians handle day-to-day production operations. Both roles are essential in biotech manufacturing but differ in responsibilities and required qualifications.

What are some common challenges faced by Biotech Process Engineers during scale-up from laboratory to production?

Biotech Process Engineers often encounter challenges when scaling up processes from laboratory or pilot scale to full production. These challenges can include maintaining product consistency, ensuring process sterility, and adapting equipment to handle larger volumes without compromising yield or quality. Engineers must also collaborate closely with cross-functional teams such as quality assurance, validation, and manufacturing to implement changes efficiently and adhere to regulatory standards. Proactive problem-solving and strong communication skills are key to overcoming these hurdles and ensuring successful technology transfer.

What does a Biotech Process Engineer do?

A Biotech Process Engineer designs, develops, and optimizes processes used in the production of biological products such as pharmaceuticals, vaccines, and biofuels. They work closely with scientists and manufacturing teams to scale up lab procedures to industrial levels while ensuring product quality and regulatory compliance. Their role often involves troubleshooting equipment, improving efficiency, and implementing new technologies within biotech manufacturing environments.

What are the key skills and qualifications needed to thrive as a Biotech Process Engineer, and why are they important?

To thrive as a Biotech Process Engineer, you need a solid background in chemical or biochemical engineering, process design, and regulatory compliance, typically supported by a relevant bachelor's or master's degree. Familiarity with process control systems, bioprocess simulation software, and industry-standard quality systems such as cGMP is essential. Strong analytical thinking, problem-solving abilities, and effective teamwork and communication skills help you excel in cross-functional environments. These skills ensure efficient, compliant, and innovative bioprocess operations, which are critical for product quality and organizational success.
Infographic showing various Biotech Process Engineer job openings in Boston, MA as of August 2026, with employment types broken down into 79% Full Time, and 21% Contract. Highlights an 79% In-person, 7% Hybrid, and 14% Remote job distribution, with an average salary of $99,968 per year, or $48.1 per hour.

Downstream Process Development, Engineer II

Takeda Pharmaceutical Company Limited

Lexington, MA • On-site

Full-time

Dental, Vision, Life, Retirement, PTO

Posted 23 days ago


Takeda Pharmaceuticals rating

7.3

Company rating: 7.3 out of 10

Based on 71 frontline employees who took The Breakroom Quiz

69th of 86 rated pharmaceutical


Job description

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.
Job Description
Join Takeda as a Downstream Process Development, Engineer II. As an early-career professional, you handle problems of limited scope and complexity, adhering to established policies and procedures. Your decision-making is within a defined scope, using standardized methods to analyze situations and data. You are developing knowledge of basic principles, theories, and concepts, and beginning to apply industry practices and standards. Typically, this role requires some relevant experience, with contributions mostly related to task-specific activities. Your primary contacts are with your immediate team, and you work under moderate direction and close supervision, following specific, detailed instructions.
About the role:
The Downstream Process Development, Engineer II is responsible for supporting downstream biotherapeutics process development through hands-on purification and recovery development experiments. This individual contributor role supports process development across multiple scales, from micro scale through bench and pilot scale, and contributes to both early-stage and late-stage programs. You will work in teams with more senior process engineers to collaboratively execute larger experiments, while also working closely with process development team members to generate data, maintain accurate records, and contribute to the development and optimization of downstream processes.
How you will contribute:
• Execute chromatography, harvest operations, ultrafiltration and diafiltration (UF/DF), and viral clearance experiments with additional potential support of bioconjugation.
• Support downstream process development across micro scale, bench scale, and pilot scale studies
• Help maintain laboratory equipment and support routine readiness of instruments used in process development work
• Work with more senior process engineers to collaboratively plan and execute larger experiments and study activities
• Document experimental work in electronic laboratory notebooks and maintain clear, complete, and timely records
• Perform basic data analysis to review trends, compare conditions, and support study conclusions
• Prepare technical summaries, study updates, and other written materials to share results and findings
• Follow established laboratory and process development procedures, including quality and safety requirements
• Contribute to continuous improvement efforts by identifying ways to improve workflows, data capture, and experimental execution
• Assist with small projects or specific project tasks under close supervision
What you bring to Takeda:
• Associate degree with 2+ years of relevant experience, or bachelor's degree with relevant experience, in chemical engineering, chemistry, biochemistry, biotechnology, or a related field
• Experience with chromatography, harvest, ultrafiltration and diafiltration, and viral clearance steps
• Comfort with emerging digital tools and openness to AI-enabled processes that support data analysis, documentation, and workflow improvement.
• Experience with basic bioprocess control systems
• Experience using electronic laboratory notebooks for study documentation/data entry
• Ability to perform basic data analysis and present results clearly in written form
• Familiarity with technical writing for laboratory reports or development documents
• Understanding of laboratory practices, process development methods, and quality requirements
• Ability to follow detailed procedures, maintain accurate records, and work under close supervision
• Some relevant experience in process development, protein purification, or a related laboratory setting
Important Considerations:
At Takeda, our patients rely on us to deliver quality products. As a result, we must follow strict rules in our manufacturing facilities to ensure we are not endangering the quality of the product. In this role, you may:
  • Work in a controlled environment requiring special gowning and wear protective clothing over the head, face, hands, feet and body. This may include additional hearing protection for loud areas.
  • Need to remove all make-up, jewelry, contact lenses, nail polish and/or artificial fingernails while in the manufacturing environment.
  • Work in a cold, wet environment.
  • Work multiple shifts, including weekends, or be asked to work supplemental hours, as necessary.
  • Work around chemicals such as alcohol, acids, buffers and Celite that may require respiratory protection.

More about us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
#GMSGQ #ZR1 #LI-MA1
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Lexington, MA
U.S. Base Salary Range:
$71,800.00 - $112,860.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
Lexington, MA
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time
Job Exempt
Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

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