Upstream Process Engineer Jobs in Boston, MA (NOW HIRING)

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Job DescriptionAbout the role

The Process Development Engineer IV supports upstream cell culture development for both early- and late-stage biotherapeutics programs. In this role, you will design and execute studies, generate and interpret data, and advance processes using a range of upstream technologies, including bench-top bioreactors, Ambr microscale bioreactors, shake flasks, WAVE bioreactors, and high-throughput purification systems.

You will work cross-functionally with upstream, downstream, and analytical teams to support program objectives, while contributing to technical documentation and leveraging process control systems such as DeltaV. This position also offers the opportunity to explore and apply emerging tools, including artificial intelligence and in silico approaches, to improve development speed and efficiency.

How you will contribute

• Support the design and execution of upstream development studies across early- and late-stage programs

• Collaborate with upstream, downstream, and analytical teams as part of cross-functional development efforts

• Operate and troubleshoot cell culture systems, including bench-top bioreactors, Ambr, shake flasks, WAVE bioreactors, and high-throughput purification systems

• Utilize DeltaV or similar control systems to support process execution and data collection

• Maintain accurate and timely documentation in electronic laboratory notebooks

• Analyze process data, interpret results, and summarize findings to support development decisions

• Prepare technical reports, study summaries, and supporting documentation

• Learn and apply artificial intelligence and in silico tools to enhance process understanding and efficiency

What you bring to Takeda

• Bachelor's degree with 5+ years, or Master's degree with 3+ years of relevant experience in biochemical engineering, chemical engineering, biotechnology, biology, or related field

• Experience in biotherapeutics upstream process development

• Hands-on experience with upstream unit operations, including bioreactors (bench-top and Ambr), shake flasks, and WAVE systems

• Working knowledge of DeltaV or similar process control systems

• Experience using electronic laboratory notebooks

• Strong data analysis and technical writing skills

• Solid understanding of upstream cell culture process development

• Ability to learn and apply new tools and technologies, including AI and in silico methods

• Strong attention to detail with the ability to work independently and collaboratively

• Proven ability to contribute to team objectives and support broader project goals

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Empowering our people to shine:

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Lexington, MA

U.S. Base Salary Range:

$103,500.00 - $162,690.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

LocationsLexington, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Job Exempt

YesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.