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Bioinformatics Programmer Jobs in California (NOW HIRING)

Arc Institute

Scientist, Bioinformatics

Palo Alto, CA · On-site

They are seeking a Bioinformatics Scientist to develop and implement computational approaches for ... software engineering practices. • Run the production pipelines for large-scale production ...

LLNL

Bioinformatics Scientist

Livermore, CA · On-site

We have an opening for a Bioinformatics Scientist to conduct research, training, and evaluating ... Significant experience with high-performance computing, GPU programming, parallel programming ...

LLNL

Bioinformatics Scientist

Livermore, CA · On-site

We have an opening for a Bioinformatics Scientist to conduct research, training, and evaluating ... Significant experience with high-performance computing, GPU programming, parallel programming ...

LLNL

Bioinformatics Scientist

Livermore, CA · On-site

$9.8K/wk

We have an opening for a Bioinformatics Scientist to conduct research, training, and evaluating ... Significant experience with high-performance computing, GPU programming, parallel programming ...

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Bioinformatics Programmer information

See California salary details

$70.8K

$143.4K

$255K

How much do bioinformatics programmer jobs pay per year?

As of Jul 4, 2026, the average yearly pay for bioinformatics programmer in California is $143,416.00, according to ZipRecruiter salary data. Most workers in this role earn between $96,900.00 and $175,700.00 per year, depending on experience, location, and employer.

What is a Bioinformatics Programmer job?

A Bioinformatics Programmer is a professional who develops and maintains software tools to analyze biological data, such as DNA sequences, protein structures, and genomic variations. They work at the intersection of computer science and biology, using programming languages like Python, R, and Java to process and visualize complex biological datasets. Their role is crucial in fields like genomics, drug discovery, and biomedical research, where they help automate data analysis and support scientific investigations.

What are the key skills and qualifications needed to thrive in the Bioinformatics Programmer position, and why are they important?

To thrive as a Bioinformatics Programmer, you need strong programming skills (often in Python, R, or Java), a solid background in biology or life sciences, and experience working with large-scale biological data. Commonly used tools and systems include bioinformatics software like BLAST, Bioconductor, cloud computing platforms, and version control systems such as Git, and certifications in relevant domains can be advantageous. Critical thinking, problem-solving, and effective communication are essential soft skills for integrating research findings and collaborating with interdisciplinary teams. These skills ensure you can develop robust, accurate computational solutions that drive advances in biological research and healthcare applications.

What does a typical day look like for a Bioinformatics Programmer?

A typical day for a Bioinformatics Programmer involves writing and optimizing code to analyze large datasets, commonly derived from genomics, proteomics, or clinical studies. You'll spend time collaborating with biologists, statisticians, and other programmers to design experiments, validate results, and interpret findings. Most roles also include maintaining data pipelines, troubleshooting software issues, and staying updated with the latest bioinformatics tools and research. The work environment often blends independent coding with regular team meetings and project updates, offering both technical and interdisciplinary challenges. This dynamic workflow makes the role both intellectually stimulating and impactful in advancing scientific discoveries.

What are the most commonly searched types of Bioinformatics Programmer jobs in California? The most popular types of Bioinformatics Programmer jobs in California are:
What are popular job titles related to Bioinformatics Programmer jobs in California? For Bioinformatics Programmer jobs in California, the most frequently searched job titles are:
What job categories do people searching Bioinformatics Programmer jobs in California look for? The top searched job categories for Bioinformatics Programmer jobs in California are:
What cities in California are hiring for Bioinformatics Programmer jobs? Cities in California with the most Bioinformatics Programmer job openings:
What are popular job titles related to Bioinformatics Programmer jobs in CA? For Bioinformatics Programmer jobs in CA, the most frequently searched job titles are:
Bioinformatics Programmer jobs near you
Infographic showing various Bioinformatics Programmer job openings in California as of June 2026, with employment types broken down into 92% Full Time, 6% Part Time, 1% Temporary, and 1% Nights. Highlights an 79% Physical, 3% Hybrid, and 18% Remote job distribution, with an average salary of $143,416 per year, or $69 per hour.

Sr. Manager, Bioinformatics

F. Hoffmann-La Roche Ltd

Santa Clara, CA • On-site

$170K - $316K/yr

Full-time

Posted 17 days ago

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
The Position
Roche is working to improve DNA sequencing data analysis. Roche is innovating new approaches that fundamentally change when and where DNA sequencing gets processed. Our goal is to analyze data as it's generated, where it's generated.
We are seeking a visionary and deeply technical leader to champion the customer-facing bioinformatics and software strategy for our revolutionary Axeliossequencing platform. As we launch XOOS-our cutting-edge ecosystem of bioinformatics tools-you will be the bridge between our pioneering new customers and our internal development teams.
This is not a traditional role. You will lead an elite team of bioinformatics scientists and software engineers to create bespoke, high-impact solutions, resolve sophisticated technical roadblocks, and even engage in collaborative research with early adopters. Because the Axelios platform operates on a completely different paradigm than traditional Sequencing-by-Synthesis (SBS), you will be instrumental in educating the market, ensuring seamless migration to our tools, and translating complex customer feedback into actionable development pipelines.
The Opportunity
  • Customer Advocacy & Technical Enablement: Serve as the primary executive-level technical contact for new customers, driving deep adoption of the XOOS bioinformatics ecosystem across major clinical and research applications.
  • Team Leadership: Build, inspire, and manage a high-performing team of customer-facing bioinformatics scientists and solutions architects.
  • Bespoke Solution Engineering: Lead the creation of customized workflows, data analysis pipelines, and software integrations to solve unique customer pain points and accelerate Axelios platform adoption.
  • Collaborative Research: Partner with strategic early-adopter customers on collaborative research projects, co-authoring whitepapers, and demonstrating the unique capabilities of Axelios non-SBS data.
  • Cross-Functional Feedback Loop: Act as a critical strategic partner to internal Bioinformatics and Software R&D teams, synthesizing market requirements, feature requests, and technical friction points into the product roadmap.
  • Commercial & Technical Strategy: Collaborate with Sales and Product Management to support high-value customer engagements, technical evaluations, and complex contract closures.

This position is based on-site in Santa Clara, CA or San Diego, CA. (This is a hybrid position.)
Relocation benefits are not being offered for this role.
Who You Are:
(Required)
  • You have a Ph.D.in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field with 4+ years of industry experience; or a Master's degree in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field with 6+ years of industry experience.
  • You have 8+ years of progressive experience in next-generation sequencing (NGS) bioinformatics, with a demonstrated track record of leadership in an industry setting.
  • You have a significant level of expertise and comprehensive knowledge of the NGS landscape, clinical genomics space, and secondary/tertiary data analysis pipelines.
  • You demonstrated leadership experience.
  • You have a high level of proficiency with cloud architectures (AWS, Azure, or GCP), modern software development practices, pipeline frameworks (e.g., Nextflow, Snakemake), and scripting languages (Python, R).
  • You have demonstrated experience in product commercialization, go-to-market execution, or technical customer enablement (similar to scaling platforms like DRAGEN).

Preferred:
  • You have demonstrated experience working with non-SBS technologies (e.g., long-read sequencing or alternative modalities)
  • You have exceptional communication, presentation, and relationship-building skills. You have the demonstrated ability to navigate complex, sensitive technical discussions with world-class clinical and scientific executives.
  • You have the ability to navigate the complexities of a global organization, adapt to changing business needs and work collaboratively within a diverse and inclusive environment.
  • You have excellent organizational skills, including the ability to efficiently evaluate, prioritize and handle multiple changing projects and priorities; you complete work in a timely, accurate and thorough manner.

The expected salary range for this position based on the primary location of Santa Clara, CA is $170,500 - $316,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.
This position also qualifies for the benefits detailed at the link provided below.
Benefits
#NMK62026DIA
Who we are
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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